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      community Why is scalp DHT suppression lower than systemic?

      in Finasteride/Dutasteride  11 upvotes 8 months ago
      Dutasteride reduces DHT more effectively in hair follicles than finasteride, but some individuals still experience hair loss despite treatment. Combining oral and topical finasteride may improve results, and some users experiment with topical dutasteride despite uncertainties about its absorption.

      community Sharing My Routine – Hope It Helps Someone Else Too

      in Progress Pictures  638 upvotes 10 months ago
      The conversation discusses a user's positive experience with a hair loss treatment routine involving dutasteride, oral minoxidil, and Nourkrin Man, with no side effects reported. Other users share their experiences with similar treatments, discussing side effects like heart palpitations and depression, and offer advice on obtaining prescriptions affordably.

      community My Journey on Fin + Min (19M giving up)

      in Finasteride/Dutasteride  17 upvotes 1 year ago
      A 19-year-old tried oral minoxidil and finasteride for hair loss but experienced side effects like fatigue, dry eyes, and lack of motivation, leading to discontinuation. Suggestions included trying topical treatments, dutasteride, or accepting hair loss.

      community Progress after 5 months of 0.5 mg Dutasteride and 2.5 Mg oral minoxidil. I am considering a transplant eventually so strengthening the base area and doner areas. Suggestions on if I should continue the dosage for sometime before opting for a transplant or should I immediately go for it?

      in Progress Pictures  34 upvotes 1 year ago
      OP is using 0.5 mg Dutasteride and 2.5 mg oral Minoxidil for hair loss and considering a hair transplant. Most users suggest waiting 1-2 years to maximize results from the medication before opting for a transplant.

      community 5 year update on Finasteride and Minoxidil

      in Progress Pictures  422 upvotes 1 year ago
      The user has used finasteride and minoxidil for five years to slow hair loss but hasn't seen regrowth. They are considering increasing finasteride dosage, switching to dutasteride, and exploring microneedling and oral minoxidil.

      community How true is the statement: dead follicles don't grow back?

      in Research/Science  111 upvotes 1 year ago
      Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.

      community Got my first batch of 0.5 dutasteride. Hesitant to start.

      in Finasteride/Dutasteride  3 upvotes 1 year ago
      The conversation discusses a user's hesitation to start dutasteride for hair loss while already using finasteride, minoxidil (both oral and topical), RU58841, and ketoconazole shampoo. The user plans to gradually transition from finasteride to dutasteride to minimize shedding, seeking advice and reassurance from others.

      community 15 years of finasteride/minoxidil

      in Update  194 upvotes 2 years ago
      A user shared a 15-year experience using minoxidil and finasteride for hair loss, stating that despite never missing a dose, their hairline continued to recede slowly. Other users suggested that the hair loss might be exacerbated by the use of steroids and recommended considering other treatments like dutasteride and RU58841.

      community I solved my scalp inflammation

      in Treatment  30 upvotes 2 years ago
      A user solved their 15-year scalp inflammation and related hair loss using Selenium Sulfide shampoo (Selsun Blue), noticing improvement after the first use and resolution after three uses. Others found relief with Ketoconazole shampoo, which also helps with hair loss.

      community Started June 8th, 3 month update

      in Progress Pictures  127 upvotes 2 years ago
      A user started using Happyhead Dut and Minoxidil topical for hair loss, skipping finasteride. They've seen progress in three months, with slight shedding initially, and have not used finasteride before.

      community Progress pictures after using minoxidil and finasteride topical.

      in Progress Pictures 3 years ago
      This post by "vicky8201" documents their progress in treating hair loss with Minoxidil and Finasteride, which resulted in a transition from NW4 to NW2.5 over the course of two months. Master_Blaster999 and lovindicks both commented on the results, noting that it is nearly impossible to grow that much hair in such a short time frame.

      community Is pyrilutamide safe to use or still unknown?

      in Research/Science  12 upvotes 3 years ago
      The conversation is about the safety and effects of using pyrilutamide for hair loss. One person reported severe negative effects, another experienced minor side effects without much benefit for hair, and a third found the anecdote helpful in making a decision.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community Throwing Fluridil (Eucapil) into the mix.

      in Product  6 upvotes 5 years ago
      A user named "tresslessinseattle" receiving a mysterious package of Eucapil hair loss treatment, which they are considering in combination with Minoxidil and Finasteride treatments to boost the regrowth they have been seeing.

      community Low-dose oral minoxidil and skin aging

      in Minoxidil  7 upvotes 7 years ago
      The conversation discusses the use of low-dose oral minoxidil for hair loss and its potential effects on skin aging. Users shared experiences, with some noting side effects like puffy eyelids and dark circles, but no conclusive evidence of significant collagen depletion or increased wrinkles.

      community Guys anyone on dutasteride mesotherapy? 26M

      in Finasteride/Dutasteride  4 upvotes 1 year ago
      A 26-year-old is undergoing dutasteride mesotherapy with cuticapil serum and minoxidil tablets for hair loss, expecting results in a few months. The treatment is monthly, costs 4750 INR per session, and has shown no noticeable side effects so far.

      community 6 months topical liquid min & oral fin

      in Progress Pictures  11 upvotes 1 year ago
      The user completed 6 months of using topical liquid minoxidil and oral finasteride, experiencing initial hair shedding followed by gradual regrowth after 2 months. They also dealt with dandruff and reported no negative impact on sex drive.

      community Did UCLA Just Cure Baldness? Check this Out!

      in Research/Science  968 upvotes 1 year ago
      UCLA's PP405 shows promise in reactivating dormant hair follicles for hair loss treatment but is still in clinical trials. Minoxidil and finasteride remain common treatments until PP405 becomes available.

      community Does everything that reduces DHT block 5ar?

      in Treatment  46 upvotes 2 years ago
      Finasteride is the most effective treatment for reducing DHT and addressing hair loss compared to fish oil and saw palmetto. Topical treatments like RU58841 and minoxidil are also discussed, but finasteride remains the most effective option.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 2 years ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

      community Bimatoprost (Latisse)?

       4 upvotes 12 years ago
      Bimatoprost (Latisse) may help with hair thinning but is expensive and less effective than minoxidil or finasteride. Combining treatments like minoxidil, finasteride, and possibly RU58841 could be more effective for hair loss.

      community New Treatments, and a Huge Group Buy with Lots of Research

      in Research/Science  109 upvotes 2 years ago
      A user is organizing a group buy for various compounds aimed at reversing hair loss and gray hair, and improving brain health and fat loss. The user has developed a treatment plan based on extensive research and is inviting others to participate, with the option to choose only the compounds they need.

      community Update: going nuclear! (Switch to dut)

      in Update  13 upvotes 1 month ago
      The user had a hair transplant in March 2025 and has been using finasteride since 2023, which halted hair loss but didn't fully restore density. They plan to use dutasteride twice weekly, finasteride five times a week, and saw palmetto to improve hair thickness.

      community Minoxidil & Dutasteride - 4-5 month progress update

      in Progress Pictures  24 upvotes 1 month ago
      The user reports feeling more confident and happier after 4-5 months of using Minoxidil and Dutasteride for hair loss. Some users debate the effectiveness of the progress pictures, with differing opinions on visible hair density improvement.