Pyrilutamide (KX-826) is discussed as an anti-androgen treatment for hair loss, with mixed user experiences. Some users report no results, while others find it mildly effective.
Finasteride can cause dry eyes and vision issues due to its impact on the meibomian glands. Users have mixed experiences, with some experiencing eye discomfort and others having no side effects.
The user has been using a finasteride and minoxidil combo spray from Hims for four months, with positive results and no side effects. They apply four sprays nightly, targeting the crown and front of the scalp.
The user experienced significant hair regrowth using oral minoxidil, finasteride, and topical dutasteride, with no side effects. They plan to continue these treatments long-term to maintain results.
Way-316606 is considered a potential hair loss treatment but is avoided due to safety concerns and lack of research. Minoxidil and Finasteride are preferred as established treatments.
RU58841 is discussed as a potential hair loss treatment, with comparisons to finasteride. There is interest in leaked trial data, but no official clinical validation or approval for RU58841.
KX826 shows promise as a hair loss treatment with a 10% increase in hair count, but concerns about Kintor's marketing practices and the systemic effects of treatments like GT20029 and RU58841 remain. Users express skepticism and hope, with some preferring traditional treatments like finasteride and minoxidil.
The conversation discusses using minoxidil and finasteride for hair loss, with concerns about absorption and considering adding tretinoin for better results. Microneedling is suggested as a method to improve absorption, with varying depths and frequencies recommended.
The conversation discusses using Pyrilutamide 1% as a potential treatment for hair loss, with some users combining it with minoxidil and finasteride. Experiences vary, with some reporting shedding and no progress, while others remain hopeful for future results.
Silicone and dimethicone in shampoos may hinder Minoxidil absorption, while Tretinoin and microneedling can enhance its efficacy. Users discuss applying Tretinoin before Minoxidil, waiting for it to dry first.
The conversation discusses skepticism and mixed opinions about a hair loss theory, mentioning treatments like Minoxidil, finasteride, RU58841, and Procyanidin B2. There is criticism of a content creator named HairCafe and the difficulty in obtaining effective sulforaphane supplements.
The user is experiencing hair regrowth using oral minoxidil, finasteride, dermastamping, and ketoconazole shampoo. Suggestions include adding pyrilutamide or considering dutasteride instead of finasteride.
The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.
OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.
Pyrilutamide is a selective AR antagonist with a high binding affinity, making it effective in competing with DHT for androgen receptors. The 1% concentration is more effective than the 0.5%, but the latter may suffice for mild hair loss; the drug is considered a good option for those avoiding 5AR blockers due to side effects.
A user bought questionable RU58841 powder from AliExpress and seeks a way to test its composition in Europe. Another user suggests using Janoshik for testing.
The conversation is about using adenosine, finasteride, and minoxidil for hair loss treatment. The user ordered a 0.75% adenosine solution and is currently using finasteride 1mg and minoxidil 5%.
A user is creating a custom topical hair regrowth serum using minoxidil, bimatoprost, tretinoin, castor oil, and hyaluronic acid. They are also using dutasteride, oral minoxidil, and castor oil in their current regimen.
The conversation is about whether topical finasteride and minoxidil need to be applied directly to the affected areas of the scalp or if they can be spread through blood vessels. It also asks how long topical finasteride remains on a pillow.
GT20029, a new hair loss treatment, shows promising results but only a slight improvement over placebo. People are cautiously optimistic, discussing its potential and combining it with existing treatments like Minoxidil and Finasteride.
The conversation discusses hair regrowth after nearly 7 months of using 1mg finasteride and dermarolling, with some users noticing thicker hair and improved density. Minoxidil was suggested but ruled out due to the user's cats, and a hair transplant was mentioned as a potential solution for completely bald areas.
The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.
A user on .5 mg of dutasteride for hair loss saw no improvement and is considering increasing to 2.5 mg but is unsure of its effectiveness. Another user mentioned that 2.5 mg reduces scalp DHT more and increases hair count more than .5 mg, but the cost and side effects should be considered.
The user wants to try using 0.025% topical finasteride every day by diluting their 0.1% topical finasteride with alfatradiol, and is asking if it's possible to mix them or if there are other options. They heard that alfatradiol might not be suitable for this purpose.
The conversation is about someone's positive results after one month using RU58841 and minoxidil 5% once a day for hair loss. RU58841 is a topical solution that prevents DHT hormone from binding to hair follicles.
A new hair loss treatment called TDM-105795 is discussed as a potential replacement or add-on to Minoxidil. Users express hope for new effective treatments.
The conversation is about the impressive hair density and hairline of a person, with users attributing it to good genetics and joking about the lack of hair loss despite stress. Specific hair loss treatments like Minoxidil, Finasteride, or RU58841 are not discussed.
A user is using a compounded hair loss treatment with 5% minoxidil, 0.005% finasteride, and 0.01% tretinoin but is experiencing issues with residue and greasiness. They are inquiring if using the treatment five times a week instead of daily will still be effective.
A 22-year-old male using finasteride, minoxidil, and derma stamping for one month reports progress in hair loss treatment. He also uses vitamin D, omega-3, beta carotene, tongkat ali, and ag powder, and maintains an active lifestyle.
The conversation is about a user seeking information on a clinical trial by Amplifica - Scube3 for Androgenetic Alopecia (AGA). The user is unsure if it's a formal phase 1 study.