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      community Does anyone have experience with topical dut?

      in Finasteride/Dutasteride  8 upvotes 3 years ago
      The user has been using minoxidil for hair loss and is considering trying a compounded topical treatment with 0.1% dutasteride, minoxidil, tretinoin, collagen, and silicon, as recommended by a trichologist. They learned that dutasteride might be more effective than finasteride and are seeking opinions on the use of topical dutasteride.

      community Koshinemall is official site, confirmed

      in Research/Science  3 upvotes 1 year ago
      A user confirmed that koshinemall.com is the official site for buying Pyrilutamide after contacting Kintor directly. They expressed initial skepticism due to the website's quality and phone number requirement.

      community Follow up appointment with Donovan.

      in Finasteride/Dutasteride  17 upvotes 2 years ago
      The user was diagnosed with DUPA and initially treated with finasteride, then switched to dutasteride which worsened their hair loss. They are now returning to finasteride and adding treatments including oral minoxidil, Proscar, Viviscal, pumpkin seed oil, LLLT, and Nizoral shampoo, hoping for hair regrowth.

      community Diy dutesteride please help MCT oil or PG?

      in Finasteride/Dutasteride  1 upvotes 4 months ago
      A user is making their own dutasteride solution using MCT oil but is concerned about its effectiveness and bioavailability. They are considering using propylene glycol or adding ethanol for better results, while others suggest the current dosage might be excessive.

      community SUBE3 for sale in the gray market?

      in Chat  5 upvotes 1 year ago
      SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.

      community Dutas and Minox results - mixed feelings

      in Finasteride/Dutasteride  239 upvotes 5 months ago
      A user experienced significant hair growth using oral dutasteride and minoxidil but developed severe erectile dysfunction, likely exacerbated by obesity and diabetes. They plan to lose weight and possibly adjust medication to alleviate side effects.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community This is just asking for help. Not blaming minoxidil or finas

      in General  86 upvotes 1 year ago
      The user experienced constipation and gas issues possibly linked to Minoxidil and Dutas use, leading them to stop and later restart Minoxidil without lactose. They recently began using finasteride and are awaiting a SIBO test to understand their gastrointestinal issues.

      community Starting Pyrilutamide BID. First dose was yesterday. Diffuse thinning. I will put my full regimen below.

      in Research/Science  89 upvotes 3 years ago
      A user's regimen to help with their diffuse thinning, which includes taking Pyrilutamide BID, 1mg finasteride daily, 2.5mg oral minoxidil daily, topical minoxidil since August 2021, LLLT every two days, topical fin, progesterone, melatonin, minoxidil (started one week ago), pumpkin seed oil and not dermarolling; other commenters suggested Nizoral for dandruff control and caution when using pre-mixed products with Pyrilutamide.

      community Extreme caution: my experience using Ru58841 only once

      in Treatment  10 upvotes 1 year ago
      An 18-year-old experienced severe side effects, including heart palpitations and high blood pressure, after using RU58841 once, leading to a referral to cardiology for suspected left ventricular hypertrophy. The user regrets using RU58841 and seeks advice on recovery, while others suggest preexisting conditions or genetic predispositions may be factors.

      community Anything stronger than DUT out there?

      in Finasteride/Dutasteride  14 upvotes 2 years ago
      The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.

      community What do you think about this prescription

      in Treatment 2 years ago
      The user visited a trichologist due to ineffective topical finasteride treatment for hair loss. The trichologist recommended a new regimen including a two-month course of locoidon (cortisone 0.1%), followed by a solution containing minoxidil, hydrocortisone butirrate, estrone, progesterone, tocopherol acetate, trichosol, and transcutol.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Anyone tried Stemoxydine twice daily?

      in Treatment  5 upvotes 4 years ago
      The conversation discusses using Stemoxydine, a hair growth stimulant considered weaker than Minoxidil, and questions whether applying it twice daily could improve results similar to twice-daily Minoxidil applications.

      community How I was able to get Dut .5mg within a day.

      in Product  11 upvotes 1 year ago
      ScottMills3 shared how to quickly get a prescription for generic Dutasteride (Dut .5mg) online through MedicalWellnessCenter, which cost $69.95 for the consultation and $31 for a 90-day supply. Another user suggested hidrb.com as a cheaper alternative, offering the same prescription for $15.

      community DUT .5mg 1 YEAR & ORAL MIN 5mg

      in Update  29 upvotes 1 year ago
      The user experienced no significant improvement in hair loss despite using Dutasteride, oral Minoxidil, and previously RU58841, and is uncertain if changes in medication or stopping RU58841 worsened the condition. Some users noted no change or slight improvement, while others suggested the possibility of Dutasteride causing issues.

      community High Estrogen and Test on Dut 5x a week

      in Finasteride/Dutasteride  6 upvotes 10 months ago
      A user experienced increased pimples and cysts after two years on dutasteride, possibly due to hormonal changes. Suggestions included seeing an endocrinologist, using supplements like boron and DIM, adjusting diet, and reducing body fat to manage side effects.

      community Thinking about using PP405 and RU58841

      in Research/Science  1 upvotes 3 months ago
      The conversation is about a person using dutasteride and minoxidil for hair loss, considering adding RU58841 and PP405 for more density. They are seeking advice on using these treatments and exploring other options like GT20029.