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The user has been using a strong combination of hair loss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hair loss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hair loss, with a reply suggesting that even small amounts of DHT can cause hair loss if one is sensitive to it.

A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

The user is experiencing diffuse androgenic alopecia and is trying various treatments, including 5mg finasteride, loniten, and Formula 82D, which contains dutasteride, a steroid, and tretinoin. They report potential regrowth with Formula 82D, despite previous treatments being ineffective.

A 20-year-old male is frustrated with his dermatologist for refusing to prescribe DHT blockers like finasteride or dutasteride, instead pushing for a hair transplant despite ongoing hair thinning. The user feels dismissed and unreasonably treated, and is advised by another user to find a better dermatologist and consider finasteride or dutasteride for effective treatment.

The user has seen significant hair regrowth using a routine of minoxidil, finasteride, microneedling, scalp massage, and Nizoral. They are considering adding red light therapy and PRP to their regimen.

The user has been taking dutasteride for 9 months and is satisfied with the hair growth results. They had a hair transplant and don't want to share hairline progress.

The conversation is about an 18-year-old's progress with hair regrowth using oral Minoxidil, dermarolling, and RU58841 over three months, starting treatment after beginning to lose hair at 16. Participants are impressed with the improvement and encourage continued treatment.

A satirical discussion about a 2-year-old cat experiencing hair thinning, humorously suggesting treatments like minoxidil and finasteride. Users joke about the effectiveness and risks of these treatments.

A 19-year-old has been using oral finasteride and minoxidil for a year without noticeable results. Suggestions include adding derma-stamping, increasing ketoconazole shampoo use, and considering vitamin D testing, while acknowledging that response times vary.

A teenager experiencing hair loss is using minoxidil, a derma roller, and plans to add ketoconazole shampoo to their routine. They are advised to continue this regimen consistently for at least six months to see results, with the shedding being a normal part of the process.

The user has been experiencing hair loss since the age of 16 and has tried various treatments including minoxidil, finasteride, RU58841, microneedling, and keto 2%. Despite these efforts, there has been little improvement in hair growth. The user is considering other options such as dutasteride, perilutimide, or a hair transplant in the future, but for now, they are accepting the shaved look and focusing on personal growth and school.

Trans women discuss using finasteride and dutasteride for hair loss and whether to continue after testosterone suppression. One user reduced dutasteride dosage after achieving undetectable testosterone levels.

Concerns about hair loss treatments like finasteride and minoxidil not being administered during a coma. Dutasteride remains in the system longer, and hair loss may not be immediate if treatment stops temporarily.

A 19-year-old male shared his negative experience with finasteride, including side effects like vision issues, genital changes, pain, swollen lymph nodes, and mood alterations, which resolved after stopping the medication. He suggests alternative hair loss treatments like exercise, diet, possibly avoiding masturbation, topical anti-androgens, and dermarolling, emphasizing mental health over aesthetics.

An 18-year-old woman experiencing hair loss due to stress, possible PCOS, and low vitamin D is concerned about starting 5% minoxidil foam, prescribed by her doctor, due to potential facial hair growth. She is also using a topical steroid for scalp sensitivity and pain.

An 18-year-old is using topical minoxidil 5% and derma rolling weekly for hair regrowth after shaving their head, while also addressing vitamin D deficiency and thyroid imbalance. They are questioning if the changes observed are signs of regrowth.

A 42-year-old male shared his hair regrowth progress using a regimen of oral dutasteride, topical minoxidil, and finasteride, along with testosterone injections. He experienced noticeable improvement in hair growth and expressed gratitude for the support and information from the community.

The conversation discusses treating male pattern baldness in a transgender woman using cyproterone acetate, finasteride, and biotin. The original poster shared their experience for others who might be in a similar situation.

Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

The user is experiencing good hair regrowth using topical minoxidil, oral finasteride, biotin, and ketoconazole shampoo. They are curious about when the regrowth will plateau.

A 19-year-old is experiencing rapidly progressing male pattern baldness and is unsure whether to start Minoxidil now or wait until they can access Finasteride. They currently use Ketoconazole shampoo and are concerned about the long-term commitment and potential shedding associated with Minoxidil.

A 19-year-old male plans to start finasteride due to hair thinning after using creatine. He seeks advice on finasteride's effectiveness, especially for Asians.

A 14-year-old is experiencing significant hair loss and was prescribed Aminexil by a dermatologist. They are concerned about potential side effects.

The conversation discusses the use of RU58841 for hair loss, with concerns about its legality in Germany and potential legal consequences. Alternatives like finasteride and dutasteride are mentioned, with some users questioning the effectiveness and safety of RU58841.

An 18-year-old with Norwood 2 hair loss is considering finasteride treatment. Bloodwork shows testosterone and hormone levels mostly within normal ranges, except for low estradiol.

RU58841, an anti-androgenic compound, showed early promise for treating alopecia but faced challenges after its patent in 1997. Despite advancing to Phase II trials, safety concerns and financial struggles led Aventis to abandon its development. Proskelia, which later merged into ProStrakan, couldn't prioritize the drug, leading to its eventual stagnation and failure to reach the market.

A user shared their positive experience with hair regrowth using minoxidil, hormone replacement therapy, and cyproterone acetate during their male-to-female transition. Another user discussed their successful hair transplant after transitioning and using finasteride, highlighting the challenges of hair loss and regrowth during transition.

The user started using finasteride (0.5mg daily) and oral minoxidil (2.5mg daily) at 18, leading to healthier, thicker hair and reduced anxiety about hair loss. They experienced no negative side effects and plan to continue the treatment.

A 16-year-old started using topical finasteride, minoxidil, and dermapen for hair regrowth, along with natural DHT blockers. Advice given includes being patient and considering waiting until 18-21 to use finasteride.

PP405's phase 2a trial results were presented, focusing on safety and pharmacokinetics, with a future meeting planned to share the full dataset. The trial includes a randomized controlled portion and an open-label extension, with no indication of phase 2B completion.