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      community Important reminder for cat owners ⚠️

      in Minoxidil  441 upvotes 9 months ago
      Minoxidil is extremely toxic to cats, even in small amounts, and can be fatal. Switching to oral minoxidil is safer for cat owners, but precautions should still be taken to prevent exposure.

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  13 upvotes 1 year ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community Fuck it, I’m ordering Pyri Topical

      in Product  12 upvotes 1 year ago
      A user plans to order Pyrilutamide for hair loss after losing ground on finasteride. Another user advises against buying from Hairliciously, suggesting Amazon instead.

      community What are your thoughts on this solution?

      in Treatment  15 upvotes 1 year ago
      The conversation discusses hair loss treatments, focusing on the use of Minoxidil, finasteride, and triamcinolone. Concerns are raised about high concentrations of Minoxidil and the long-term use of corticosteroids.

      community Topical rapamycin, metformin, a-kg grow hair

      in Research/Science  13 upvotes 5 years ago
      The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.

      community GT20029. Kintor Pharma’s Product

      in Research/Science  12 upvotes 3 years ago
      The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

      community 2 year progress on Min + Fin; transplant possible?

      in Is this regrowth?  65 upvotes 2 months ago
      An 18-year-old has been using minoxidil and finasteride for hair loss since age 15, recently adding dutasteride and GHK-Cu, but sees no significant improvement and is considering a hair transplant. Concerns are raised about using hormone suppressors at a young age, with suggestions to explore other treatments like dermarolling, diet changes, and checking for deficiencies.

      community DIY do it yourself prp, meso and other crazy procedures.

      in Technology  2 upvotes 2 years ago
      The conversation discusses DIY cosmetic procedures like PRP, mesotherapy, and micro-needling, with some users experimenting with Minoxidil, finasteride, and RU58841 for hair loss. It highlights a community of mostly older women performing these treatments themselves.

      community What to dilute Finasteride with?

      in Treatments  65 upvotes 9 months ago
      Diluting finasteride in a Hims spray can be done using ethanol or propylene glycol to maintain the desired concentration without increasing minoxidil levels. This approach ensures the finasteride concentration is reduced to 0.025% without affecting the minoxidil strength.

      community is there any news about pp405 please

      in Update  11 upvotes 1 year ago
      There is no new information on pp405, with data collection expected to finish by the end of 2025. Users are discussing the timeline for data analysis and completion of Pelage Pharmaceuticals' phase 2 study.

      community Is PP405 gonna flop or what???

      in Research/Science 4 weeks ago
      PP405 is viewed skeptically, with some seeing it as overhyped and potentially ineffective compared to existing treatments like minoxidil and finasteride. While it shows some promise in activating dormant hair follicles, many believe it won't replace hair transplants or significantly outperform current options.

      community Topical Finasteride update by H&W

      in Finasteride  28 upvotes 8 years ago
      The conversation discusses using topical finasteride for hair loss, with concerns about its safety around family members, especially pregnant women and infants. One user plans to try topical finasteride due to side effects from the pill.

      community Does anyone know the chemical formula for pelage pp405?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

      community Excited to stack Finasteride+Kx826 😃

      in Research/Science  37 upvotes 1 year ago
      The conversation is about using finasteride and KX826 for hair loss treatment. The original poster is using 0.25 mg of finasteride every other day due to side effects at a higher dose.

      community Low cortisol it is due the fin

      in Finasteride/Dutasteride  7 upvotes 9 months ago
      The user has been taking 1mg finasteride daily for a year with no improvement in hair loss and reports low cortisol levels, sleep issues, and anxiety changes. The conversation includes discussions on the potential effects of finasteride on cortisol and neurosteroids, with suggestions to consult a doctor and consider other factors.

      community M20 on Fin+Min for 1 Year – Crown Still Thin, Should I Add Dut/Oral Min?

      in Progress Pictures  26 upvotes 7 months ago
      A 20-year-old has been using finasteride and topical minoxidil for a year but is considering adding oral minoxidil, dutasteride, and biotin due to unsatisfactory results. Opinions vary, with some suggesting patience and others recommending different treatments, but caution is advised against using multiple oral drugs due to potential side effects.

      community What has the evidence been on side effects with CB?

      in Research/Science  4 upvotes 5 years ago
      Clascoterone (CB) shows an excellent safety profile with no serious side effects, but its effectiveness may decline after six months, making it more suitable as an adjunct treatment with finasteride and minoxidil rather than a standalone solution. Some argue it could be better than finasteride due to its protection against testosterone, but its long-term efficacy remains debated.

      community Coegin Pharma to release Follicopeptide (FOL005) by Q2 2025

      in Treatment  121 upvotes 1 year ago
      Follicopeptide (FOL005) by Coegin Pharma will launch as a cosmetic hair growth treatment by Q2 2025, showing similar efficacy to finasteride. Users discuss the benefits and skepticism of releasing hair loss treatments as cosmetics rather than drugs.
      Dermatologist or online consult for finasteride prescription?

      community Dermatologist or online consult for finasteride prescription?

      in General  74 upvotes 1 year ago
      An 18-year-old experiencing aggressive hair loss is considering whether to obtain a finasteride prescription through an online consult to save money instead of visiting a dermatologist. The user is seeking advice on the cost-effectiveness of these options.