RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.
The user reported worsening hair loss after 1.5 years on finasteride, questioning if chronic iron deficiency could be a cause. They noted no side effects from finasteride.
Hair loss treatments, such as Dutasteride, Minoxidil, and Finasteride. Advice is given to give the medications time to work and to consider a Hair Transplant in order to fill any gaps caused by continuing hair loss.
A 20-year-old male is unsure how to interpret his bloodwork results and whether he should take finasteride for hair loss. His bloodwork shows borderline high levels of albumin and testosterone, and high progesterone, but normal levels of other hormones.
The user shared a 4-year hair loss treatment update using oral minoxidil and dutasteride, reporting significant hair regrowth and improved hair quality. They started with finasteride before switching to dutasteride and experienced fast results in the first year, with continued improvements in hair thickness over the past two years.
Hair loss affects mental health and self-esteem, causing anxiety and depression. Treatments like finasteride, minoxidil, and hair transplants help some, but others continue to struggle.
Ketoconazole shampoo is primarily used to reduce scalp fungus and inflammation, not to block DHT or androgen receptors. It may help with seborrheic dermatitis and improve scalp health, but its effects on hair loss are minimal compared to treatments like finasteride.
Shampoos, including those with ketoconazole, may offer mild benefits for hair health but are not effective for stopping hair loss or balding. Effective treatments for hair loss include finasteride and minoxidil, often used together, while shampoos are generally not on the scalp long enough to impact hair follicles significantly.
Creatine may cause hair loss in some individuals, especially those on finasteride, despite no scientific link. Personal experiences suggest individual sensitivity to DHT could be a factor.
Oleic acid and ethanol are being considered for hair regrowth, with some users planning to self-experiment. There is skepticism about their effectiveness, and ongoing use of treatments like finasteride and minoxidil is mentioned.
A user shared their successful hair regrowth journey using finasteride for four years, initially also using Rogaine. They experienced significant improvement, regrowing their hairline and crown, and noted being a hyper responder to the treatment.
A 35-year-old man has been using Finasteride 1mg daily for 4.5 months with no noticeable effects on hair loss, and he is considering adding Minoxidil to his treatment. Other users suggest that significant improvements may take up to 18 months and recommend additional treatments like Minoxidil, microneedling, or switching to Dutasteride.
Creatine does not cause hair loss, despite many users reporting personal experiences of hair shedding. Scientific evidence shows no link between creatine and increased hair loss or hormone changes.
Creatine is not proven to cause hair loss, but some report increased shedding, especially with male pattern baldness. Finasteride or minoxidil are suggested to counteract potential hair loss while using creatine.
A person used hair fibers for 11 years to hide hair loss, which affected their social life. They had a hair transplant, improving their life, and recommend addressing hair loss directly.
Transplanting pubic and butt hair to the head is discussed humorously, highlighting pros like DHT resistance and cons like poor blending and appearance. Users joke about using treatments like Minoxidil, Finasteride, and RU58841 on unconventional donor areas.
A new drug, PP405, is being discussed as a potential cure for baldness, with hopes it could be more effective than Minoxidil and Finasteride. Users are skeptical about its effectiveness and the need for lifelong use.
Hair loss treatments include finasteride, minoxidil, microneedling, dutasteride, CB-03-01, RU-58841, and experimental options like KY-19382 and stem cell therapy. Some treatments are considered ineffective or risky, such as ketoconazole, PRP, and low-level laser therapy.
Oral minoxidil can increase body hair growth, but effects differ among individuals. Some recommend topical minoxidil to prevent unwanted body hair while preserving scalp hair.
PP405 is a potential new hair loss treatment that might replace finasteride and minoxidil, but it is still in clinical trials and may not be available until 2028-2031. There is skepticism about its effectiveness, with only a 20% increase in hair density observed in some participants.
Hair loss matters, but focusing on self-improvement like working out, using treatments like minoxidil and finasteride, and building confidence can help. People often suggest extreme solutions like becoming a millionaire or bodybuilder, but practical steps are more beneficial.
Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.
Nicotine use, especially from vaping, may worsen hair shedding and reduce the effectiveness of finasteride and dutasteride. Quitting nicotine seems to improve hair health.
Microneedling with minoxidil and finasteride greatly improves hair regrowth. Using 0.5mm depth every other day boosts minoxidil absorption without side effects.
Significant hair growth was achieved using Minoxidil 5% and dermarolling twice a week, with suggestions to add finasteride for maintenance. There is debate on when to apply Minoxidil after dermarolling to avoid irritation.
The user experienced significant hair regrowth on the crown using 1mg finasteride daily, 5% minoxidil at night, oral minoxidil 1mg, and daily vitamin D. They noted side effects like redness and dandruff from minoxidil, and others discussed the effectiveness and side effects of these treatments.
A user shared their successful hair regrowth journey using oral Propecia, topical Minoxidil, Ketozol shampoo, a derma roller, strength training, Omega 3, and Biotin. They experienced initial shedding but saw significant improvement in hair growth after 3-4 months.
Intermittent fasting may inhibit hair growth by triggering a stress response that affects hair-follicle stem cells. Some users believe genetics and DHT play a larger role in hair loss, and treatments like Minoxidil and Finasteride are mentioned as ineffective for some.
Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.