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      community Thin roots but thick ends hair – anyone else facing this?

      in Treatment  5 upvotes 2 months ago
      A 23-year-old is experiencing hair that is thick at the ends but thin at the roots despite using minoxidil and finasteride for 10 months. They are concerned about whether this is normal or a sign of miniaturization and seek advice on reversing or improving the condition.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 8 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

      community 7 month progress Min/Fin/Microneedle/Ketoconazole

      in Progress Pictures  11 upvotes 2 years ago
      The user has been treating hair loss for 7 months using a combination of pyrilutamide, a topical mix of finasteride and minoxidil, microneedling, a topical mix of GHK-Cu and minoxidil, ketoconazole shampoo, fish collagen peptides, zinc, and vitamin D3. Another user suggests that continuous small improvements could lead to significant hair regrowth over time.

      community MCL1 does anyone knows anthying about it

      in Research/Science  9 upvotes 1 year ago
      MCL-1 protein may help maintain hair follicles in the growth phase and prevent miniaturization. There is interest in experimental treatments like exosomes, peptides, or stem cell serums to upregulate MCL-1 for hair loss, especially for those not using minoxidil or finasteride.

      community Autoimmune disease and balding

      in Update  12 upvotes 1 year ago
      A user diagnosed with Crohn's disease is concerned it might contribute to balding. They have been using keto shampoo, finasteride, and oral minoxidil, which improved their hair but not significantly.

      community Question about clascoterone acne cream

      in Treatment  2 upvotes 1 month ago
      Clascoterone cream can be used on the scalp, but it may not be effective due to its dosage. AR antagonists like clascoterone are generally less effective than 5AR inhibitors for hair loss.

      community My dear dog (M9) is balding...

      in Satire  778 upvotes 2 years ago
      The conversation is a satirical discussion about a user joking that their dog is balding and needs hair loss treatments like finasteride, with others commenting on the creepiness of an AI-generated image of a dog with human features.

      community Keratin microspheres - breakthrough

      in Research/Science  14 upvotes 2 years ago
      A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

      community Ben Greenfield Podcast : CHK-Cu & C-60

      in Research/Science  5 upvotes 4 years ago
      CHK-Cu (copper peptide) and C-60 (branched carbon chain) are discussed as potentially more effective than minoxidil for hair regrowth. Some users are skeptical about the claim that DHT isn't the root cause of hair loss, and others are trying these products to see if they work.

      community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

      in Chat  9 upvotes 5 years ago
      The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community Pili migrans? Lichen something? Seb derm?

      in Female  19 upvotes 1 year ago
      The conversation is about a female experiencing hair loss and seeking advice on why it's difficult to regrow hair. Specific treatments like Minoxidil, finasteride, or RU58841 are not mentioned.

      community Suggestions?

       5 upvotes 12 years ago
      The user is experiencing chronic folliculitis with scalp sores and is concerned about a receding hairline. They have tried various treatments including antibiotics, Nizoral 2% shampoo, and lifestyle changes, but are seeking further advice.

      community lost all my gains switching from liquid to foam

       5 upvotes 7 years ago
      Switching from liquid to foam minoxidil led to hair loss for OP, possibly due to a second shedding cycle. OP experienced allergic reactions to propylene glycol in the liquid form, causing dandruff and itchiness, which improved after switching to foam.

      community Im struggling with sebderm need help

      in Product  3 upvotes 3 months ago
      The user is struggling with seborrheic dermatitis and plans to try ciclopirox olamine after finding ketoconazole too drying. They are also using finasteride daily.

      community Hydrocortisone cream

       7 upvotes 9 years ago
      A 30-year-old male with thinning hair and an itchy, oily scalp found that hydrocortisone cream eliminated dandruff and itching and seemed to thicken his hair. He avoided minoxidil and finasteride due to potential side effects and noted that Nizoral and Head & Shoulders worsened his symptoms.

      community HairClone: Good info from their site

      in Technology  10 upvotes 4 years ago
      HairClone aims to rejuvenate miniaturizing hair follicles through follicle banking and cell expansion, with treatments potentially available in the UK by 2022. The process involves extracting, storing, and cloning hair follicles, but full regenerative treatments will take many years to develop.

      community Pelage Recruiting Now for Phase 2

      in Research/Science  11 upvotes 1 year ago
      Pelage is recruiting for phase 2 trials, showing promise for treating bald regions. The discussion highlights its potential effectiveness based on its mechanism of action.

      community Minoxidil and concern about cats

      in Minoxidil  4 upvotes 11 months ago
      Minoxidil is highly toxic to cats, and even small amounts can be fatal. The user decided against using topical minoxidil due to the risk to their cats and considered oral minoxidil and ketoconazole shampoo as alternatives.

      community Cold showers = healthier scalp?

      in Chat  13 upvotes 2 years ago
      Cold showers may improve scalp health for some, reducing itchiness and dandruff, but may increase dandruff for others while improving hair texture. Individual experiences with cold showers and scalp health vary.

      community So I was thinking...

      in Ketoconazole  9 upvotes 6 years ago
      The user experienced hair thinning despite using finasteride and switched to a ketoconazole shampoo without sulfates to address scalp itching and dandruff. They hope this will stop further hair thinning.

      community 0-5 months: almost perfect hair regrowth. But now, after ten months….

      in Update  16 upvotes 1 year ago
      The user experienced significant hair regrowth with topical finasteride, minoxidil, ketoconazole, and dermarolling, but later faced severe hair shedding after stopping dermarolling and reducing ketoconazole use. Suggestions included switching to oral treatments, resuming dermarolling, and considering lifestyle changes.