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      community For those on TRT and suffer from a more aggressive type of (AGA) hairloss, what are your hair safe protocols?

      in Chat  6 upvotes 3 years ago
      People on testosterone replacement therapy (TRT) with aggressive androgenetic alopecia (AGA) discuss using Dutasteride or Finasteride, sometimes combined with topical treatments like RU58841 or CB-03-01 (Breezula), to prevent hair loss. Concerns about side effects and costs of certain treatments are mentioned, with one individual sharing their experience of slowed hair loss using Finasteride alone.

      community Is it true that most hair loss treatments fall into one of two categories? If not, what am I missing?

      in Treatment  5 upvotes 2 years ago
      Hair loss treatments are generally categorized as anti-androgens, like finasteride and RU58841, which prevent hair loss by targeting DHT, and growth stimulators, such as minoxidil, rosemary oil, microneedling, and LLLT, which promote hair growth by increasing blood flow and growth factors. The user is seeking to confirm these categories and understand if there are other treatments or mechanisms of action.

      community Zyrtec (Cetirizine) antihistamine for hair growth compared to Minoxidil NIH study

      in Minoxidil  35 upvotes 3 years ago
      The conversation discusses the potential of topical cetirizine (Zyrtec) for hair growth in comparison to minoxidil, noting cetirizine's ability to reduce prostaglandin D2, which inhibits hair growth. Users share mixed experiences with cetirizine for allergies and scalp health, and there's a mention of the risk of dementia with long-term antihistamine use.

      community Maintenance dose of Finisteride

      in Chat  1 upvotes 1 year ago
      Low doses of finasteride, even as low as 0.25 mg, can effectively prevent hair loss without significantly lowering DHT levels. Combining finasteride with natural DHT-lowering solutions may achieve similar results to higher doses.

      community Just an encouraging post for atypical alopecia sufferers

      in Treatment  4 upvotes 4 years ago
      The user experienced eyebrow hair loss and tried various treatments, including Minoxidil, a Capsaicin-based product, Latanoprost, Bimatoprost, Castor Oil, and Travoprost. Despite initial setbacks and a brutal shedding phase, they eventually saw positive results with Travoprost, encouraging others not to give up on treatments.

      community [rant] being hairless is ruining all my self esteem

      in Chat  177 upvotes 1 week ago
      Hair loss is causing distress and self-esteem issues, with discussions on treatments like finasteride, minoxidil, and hair transplants. Some suggest topical treatments or lifestyle changes, while others stress the importance of confidence and self-acceptance.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 3 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community Comparing the effect of T suppression and DHT suppression

      in Transgender  89 upvotes 1 year ago
      The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.

      community Realistic timeline for hair regeneration and follicle cloning?

      in Technology  6 upvotes 1 month ago
      Hair regeneration and follicle cloning are considered far from being feasible, with current treatments like finasteride, minoxidil, and hair transplants expected to remain dominant for the next 15-20 years. Some are hopeful that AI advancements might accelerate progress, but many remain skeptical about significant breakthroughs in the near future.

      community Minoxidil is a 5ar inhibitor according to research

      in Research/Science  148 upvotes 6 months ago
      Minoxidil may inhibit androgen receptors and affect hormonal pathways, potentially explaining its effectiveness in treating androgenetic alopecia (AGA). Users discuss its varying effectiveness on scalp versus facial hair and note fewer side effects with topical use compared to oral.

      community I wish pp405 work and i have full head of hair in 2028-2030

      in Chat  108 upvotes 5 months ago
      People are hopeful about future hair loss treatments like PP405, GT20029, and VDPHL01, while some are currently using finasteride and minoxidil. There is skepticism about the effectiveness of new treatments, and some advise against hair transplants until more promising drugs are available.

      community Finally regrowth on the crown of my head after five years and switch to Dut!

      in Progress Pictures  25 upvotes 2 years ago
      After five years of no progress with hair regrowth using oral finasteride and topical minoxidil, a person switched to a combination of topical dutasteride, minoxidil, tretinoin, ketoconazole, and hydrocortisone in November 2023 and finally saw results. They had previously experienced side effects like gynecomastia from finasteride.

      community Odd Hair Growth (Possibly More Than Genetics?)

      in Is this regrowth?  2 upvotes 1 year ago
      A 23-year-old user shares their hair regrowth journey, questioning if genetics or other factors are at play. They use Rogaine, finasteride, vitamin B12, biotin, Thera M Plus, and derma stamping, and seek advice on their regimen and hair growth patterns.

      community Upcoming treatment ideas in the future

      in Research/Science  10 upvotes 1 year ago
      Exploring future hair loss treatments, including immunosuppressants for hair transplants and hair cloning, with a focus on leveraging research from other medical fields. Current treatments like finasteride and minoxidil are effective for most, but there's a call for more funding and innovation in the hair loss industry.

      community Castor Oil + Coconut Oil + Derma Rolling

      in Treatment  5 upvotes 8 years ago
      A user is experiencing temple hair recession and is seeking alternatives to finasteride. They are considering castor oil, coconut oil, and derma rolling, and have seen some improvement with Zenegen.

      community Something not talked about in the hair transplant industry

      in Transplants  111 upvotes 6 months ago
      Hair transplant success largely depends on individual biology, with many patients needing multiple procedures to achieve satisfactory density. Even top surgeons can't guarantee results, and many people use additional treatments like Minoxidil and Finasteride.

      community Essential hair oils and other methods to maximise hair growth

      in Treatment  3 upvotes 6 months ago
      The conversation is about maximizing hair growth using treatments like oral finasteride, topical minoxidil, caffeine and ketoconazole shampoos, biotin, omega-3, vitamin D supplements, microneedling, and various hair oils such as rosemary, castor, coconut, and peppermint. Users discuss the effectiveness of these methods and share personal experiences with hair oils for scalp health and hair maintenance.

      community Is Topical Fin a Reasonable Alternative?

      in Finasteride/Dutasteride  4 upvotes 4 years ago
      A user discusses mild/moderate hair loss and considers switching from oral to topical finasteride due to past endocrine issues. They seek feedback on topical finasteride's effectiveness and reputable sources, with replies suggesting Minoxidilmax products as effective alternatives.

      community Doubts about castor oil

       5 upvotes 7 years ago
      Castor oil's effectiveness for hair growth is debated, with concerns about its impact on skin health and prostaglandin levels. Some users suggest combining it with coconut oil and using it alongside finasteride for better results, while others recommend sticking to proven synthetic treatments.

      community Does ketoconazole reduce systemic DHT by much?

      in Treatment  6 upvotes 9 months ago
      Ketoconazole shampoo does not significantly reduce systemic or scalp DHT levels and is mainly used for its anti-fungal and anti-inflammatory effects. It is not a replacement for finasteride, which is recommended by some users despite concerns about side effects.

      community HT booked, taking finasteride and losing ground?

      in I'm Starting Treatment  1 upvotes 1 month ago
      The user is concerned about hair loss despite taking finasteride and has a hair transplant scheduled. They experience scalp itching and burning, which hasn't been relieved by various treatments, and another user suggests using ghk-cu & ahk-cu serum and Koshine kx-826/pyrilutamide for relief.

      community Alternative Approach to Hair Loss: an n=1 Experiment in Bioenergetics

       7 upvotes 6 years ago
      The post discusses a holistic, bioenergetic approach to hair loss, focusing on diet, exercise, and lifestyle changes rather than traditional treatments like finasteride or minoxidil. Key dietary recommendations include fruits, milk, potatoes, butter, coconut oil, eggs, oysters, liver, and gelatin, along with moderate exercise and lifestyle adjustments to reduce stress.