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      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community My final attempt at creatine with fin

      in Product  40 upvotes 8 months ago
      Creatine may cause hair shedding and texture changes, with mixed user experiences. Combining creatine with finasteride doesn't always prevent these effects, possibly due to individual DHT sensitivity.

      community To stop or not to stop minoxidil?

      in Minoxidil  2 upvotes 2 years ago
      A female user experienced hair loss after Covid and used Minoxidil 5% but saw more hair loss over time. She also uses alfatradiol, topical MSM, and betamethasone sporadically, and is unsure if Minoxidil is beneficial.

      community started RU58841 today and am panicing

      in Treatment  8 upvotes 2 years ago
      A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.

      community Holding the line with no meds.

      in Progress Pictures  48 upvotes 10 months ago
      A 34-year-old man is using natural methods like rosemary and peppermint oil, micro-needling, and low-level laser therapy to manage hair thinning, avoiding medications like minoxidil and finasteride. Despite minimal visible progress, he values the non-medicated approach and remains consistent with his routine.

      community Topical Fin 0.1% 5% min 7 months review

      in Finasteride/Dutasteride  4 upvotes 4 years ago
      Using topical finasteride 0.1%, minoxidil 5%, and melatonin for 7 months reduced hair loss significantly, with increased libido and decreased stress tolerance. The user applies the solution once daily, uses nizoral twice weekly, and takes vitamin D and ZMA supplements.
      Can’t tolerate fin, am I screwed?

      community Can’t tolerate fin, am I screwed?

      in Finasteride  116 upvotes 11 months ago
      The user experienced sexual side effects from a topical finasteride and minoxidil combo and stopped using it after three weeks. They plan to use foam minoxidil nightly to slow hair loss and seek alternative treatments that don't affect sexual health.

      community Anyone on meds on TRT or gear??

      in Research/Science  3 upvotes 8 months ago
      The conversation discusses the use of TRT, dutasteride, minoxidil, and potentially RU58841 for hair loss. Concerns about the risk of developing Cutis verticis gyrata with minoxidil and TRT are raised.

      community Developed dark circles from Minoxidil

      in Minoxidil  4 upvotes 4 years ago
      Minoxidil can cause dark circles and skin issues, and users suggest reducing dosage or switching to foam. Supplements like vitamin C, glycine, and MSM may help with collagen production to reduce these side effects.
      I need advice on my status quo, further actions and diagnostic

      community I need advice on my status quo, further actions and diagnostic

      in General  163 upvotes 10 months ago
      The user is experiencing hair loss, possibly due to androgenic alopecia or telogen effluvium, and is considering treatments like Minoxidil, Finasteride, or RU58841. They also mention potential iron deficiency and sleep deprivation as contributing factors.

      community What's an anecdotal treatment you nevertheless swear by?

      in Product  12 upvotes 1 year ago
      Stemoxydine is highly recommended for hair loss, preferred over Minoxidil due to fewer side effects and dependency. The user also uses finasteride, Pur'ador shampoo, and suggests cold showers and spicy food as part of their routine.

      community HT booked, taking finasteride and losing ground?

      in I'm Starting Treatment  1 upvotes 2 months ago
      The user is concerned about hair loss despite taking finasteride and has a hair transplant scheduled. They experience scalp itching and burning, which hasn't been relieved by various treatments, and another user suggests using ghk-cu & ahk-cu serum and Koshine kx-826/pyrilutamide for relief.

      community how to compound topical cyclosporine

      in Treatment  8 upvotes 3 years ago
      The conversation is about compounding topical cyclosporine for hair loss, suggesting it needs an oil base like castor oil. The user seeks tips or tricks for the process.

      community Finasteride does deplete important nuero-active steroids

      in Research/Science  10 upvotes 2 years ago
      Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

      community Cmon Pyrilutamide and CosmeRNA 😭

      in Chat  36 upvotes 2 years ago
      Users discuss waiting for new hair loss treatments and share struggles with side effects from current options like Minoxidil and Finasteride. They express hope for Pyrilutamide and CosmeRNA to provide better solutions.

      community Redensyl (The Ordinary Serum)

      in Treatment  20 upvotes 6 years ago
      Redensyl, a hair loss treatment that has been claimed to be 80% more effective than minoxidil, but users have not experienced any results from using it.

      community Brutal ongoing Shed after 15 months on fin

      in Treatment  7 upvotes 2 years ago
      User is experiencing severe hair loss despite using finasteride for 15 months, losing 500 hairs a day and 50% density since June. Minoxidil with needling was ineffective, and RU58841 is too expensive and hard to obtain.

      community HMI-115 question about potential earliest access

      in Research/Science  10 upvotes 3 years ago
      Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. HMI-115, a monoclonal antibody drug, is in phase 1 and 2 trials for different conditions, but its availability on the gray market is unlikely due to high production costs.

      community Disappointing news on Breezula/CB-03-01

       20 upvotes 7 years ago
      The conversation discusses disappointment over only receiving a financial report from Cassiopea instead of trial results for Breezula/CB-03-01, a hair loss treatment. However, there is optimism as the company is advancing Breezula into Phase III trials for men, starting trials for women, and submitting an NDA for their acne product, Winlevi.