The conversation discusses the duration of hair shedding caused by RU58841. The user is stressed and seeking information on how long the shedding phase lasts.
The user plans to try finasteride again due to past side effects, considering a gradual increase starting at 0.25 mg every 5 days to reach 0.5 mg/day. They seek advice on a tapering schedule to minimize side effects.
The user used finasteride but stopped due to side effects, then used topical minoxidil for 13 months, and later added KX826/pyrilutamide for 8 months. They experienced shedding after starting pyrilutamide and use minoxidil and KX826 once daily.
The user is experiencing gradual hairline regrowth with finasteride and is considering increasing the concentration of topical finasteride and minoxidil to speed up growth. They are also using microneedling and considering adding tretinoin to their routine.
The user shared their 12-month hair regrowth progress using 1mg finasteride, 5mg oral minoxidil, and topical minoxidil. They also used a derma stamp weekly and treated seborrheic dermatitis with Mometasone and Nizoral.
A user shared an 8-month update on hair regrowth using HIMS fin/min spray and dermastamping every two weeks, showing significant improvement. Others commented on their own progress and hopes for similar results.
The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.
GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.
User discusses 4.5 months of using 0.5 DUT & 5 mg Oral Min for hair loss. They share progress pictures and discuss styling options and shedding experiences.
PP405 shows some hair growth after 4 weeks, but results are debated and expectations should be tempered. Some users compare it to minoxidil or finasteride, questioning its effectiveness and commercialization timeline.
Hair cloning may become available in 1-2 years in Japan, but widespread availability and affordability could take 7-15 years. Current treatments like finasteride are effective but may lose effectiveness over time.
The user has been using topical minoxidil and finasteride since January and added topical dutasteride last month, seeing significant hair regrowth in five months. Other users shared their experiences with similar treatments, discussed side effects, and asked for details about the user's routine.
The acne medication Winlevi, which contains Clascoterone, is available in the U.S. and may slow down hair loss until a higher concentration treatment, Breezula, is released.
The VT Reedle Shot, a skincare product using silica spicules, is discussed as a potential at-home alternative to microneedling for hair regrowth. It is suggested that different intensities may aid in hairline regrowth.
Minoxidil may cause wrinkles and dark circles, which some users report can be mitigated by adjusting dosage. Reactions vary, and while some dismiss these side effects, others experience significant changes.
The user is pleased with 4 months of progress using topical minoxidil 5%, finasteride 1mg, and dermarolling 1mm weekly. They are asking if they should expect more results before one year and if they should switch to oral minoxidil.
The conversation is about the potential benefits of Rapamycin for hair pigmentation and regeneration, based on effects observed in mice. The original poster is seeking personal experiences from others using Rapamycin for longevity.
Regrowth is more likely if hair follicles are still alive, regardless of age, but younger individuals often see better results due to early intervention. Treatments like finasteride, minoxidil, and dermarolling can help, but results vary based on individual factors such as the presence of miniaturized hairs and the speed of treatment initiation.
KX-826 Phase II results show that a 0.5% concentration performs better than 1% for treating male pattern baldness. Concerns about receptor upregulation from long-term DHT antagonism were mentioned.
The conversation discusses an interview with Dr. Tsuji about hair follicle stem cell multiplication and the financial challenges of starting human clinical trials. It also mentions the need for funding to secure a patent for a protein that promotes hair growth.
People are discussing the use of topical melatonin for hair loss and how often it should be applied, with one person noting it makes them groggy in the morning. They are inquiring about others' application frequency.
Dutasteride takes 1-3 months to affect scalp DHT levels, not just a week. The prostate absorbs Dutasteride faster than the scalp due to different vascular networks and enzyme densities.
Microneedling frequency and depth, with suggested protocols involving 0.3mm every day before applying topical treatments like Minoxidil or Finasteride, and 0.5-1.5mm once or twice a month for wounding.
The conversation is about using a Dr. Pen for microneedling on a widow's peak, with advice to use a depth of 1.25mm and hold it in place for 10 seconds. The user is also using minoxidil.
The conclusion of the conversation is that the user, Michael_Scott1234, has been using topical minoxidil for a long time and recently started using oral finasteride and dermarolling. They have not experienced any side effects from finasteride and are happy with their progress.
After 6 months on Minoxidil and finasteride, the user sees minimal new hair growth and questions if it's a sign of slow progress or ineffectiveness. Another user suggests maximum improvement with these treatments can take up to 2 years.
PP405 is a promising molecule that may reactivate dormant hair follicles, potentially offering a new treatment for hair loss. It is in phase 2 trials, with possible availability between 2027 and 2030.
A user shared their hair regrowth progress using 2% minoxidil, 5% minoxidil spray, 1mg/day finasteride, and dermarolling/stamping. They reported no side effects except dry hair from the minoxidil.
A user's successful hair regrowth over 33 months using daily finasteride and minoxidil, microneedling 2-4 times per month, and maintaining a healthy lifestyle. The user's progress has inspired others to consider similar treatments for hair loss.