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      community Effects of 2% vs 5% min for sebderm

      in Minoxidil  1 upvotes 1 year ago
      Switching from 2% liquid minoxidil to 5% foam minoxidil reduced scalp irritation but increased eyebrow flakiness and thinning. The user speculates that propylene glycol in the liquid formulation might have been protecting against seborrheic dermatitis while causing contact dermatitis.

      community Clascoterone ph3 results ready

      in Research/Science  10 upvotes 4 months ago
      Clascoterone 5% solution showed a 539% improvement in hair count compared to placebo, but the actual increase in hair growth is minimal. Users express skepticism about the effectiveness of hair loss treatments.

      community Pyrilutamide kintor pharmaceutical

      in Chat  6 upvotes 2 years ago
      The conversation is about seeking information on GT20029 from Kintor Pharmaceutical as a potential hair loss cure and inquiring about experiences with CosmeaRNA.

      community Clascoterone phase 3 results are out!

      in Treatment  80 upvotes 4 months ago
      Clascoterone phase 3 results show promising improvements in hair count, but concerns about high costs and lack of detailed data remain. Users compare it to existing treatments like Minoxidil and Finasteride, expressing skepticism about its accessibility and effectiveness.

      community Ru58841 completely got rid of my seb derm

      in Chat  6 upvotes 2 years ago
      RU58841 cured seborrheic dermatitis, oily scalp, dandruff, and scalp pain, improving hair health when combined with Minoxidil. Another user noted diet impacts their seborrheic dermatitis and that finasteride hasn't changed their condition.

      community Brief update clascoterone phase 3 - Breezula

      in Research/Science  4 upvotes 2 years ago
      Cosmo Pharmaceuticals has enrolled about 850 out of 1400 patients for their phase 3 clinical trials of clascoterone (Breezula) and claims to be on schedule. The conversation is about hair loss treatments.

      community Looks like I’m allergic to propylene glycol..

      in Minoxidil  4 upvotes 3 years ago
      The user is experiencing an allergic reaction to propylene glycol in Kirkland minoxidil and is considering switching to a foam version or a low-PG minoxidil solution. They are also contemplating oral minoxidil but are concerned about its long-term safety.

      community Anagenic is trying to compound Gt20029

      in Treatment  57 upvotes 3 years ago
      The conversation discusses concerns that Anagenic's version of GT20029 might not be as effective or safe as Kintor's, with comparisons to issues faced by pyrilutamide. The chemical structure of the drug has been published.

      community Female AGA - Low Cortisol/Low DHEA

      in Female  7 upvotes 2 years ago
      Female (37) experiencing hair loss for 5 years, tried max dose of spiro and oral + topical minox without success. Discovered low cortisol and low DHEA levels, seeking functional medicine practitioner for help.

      community Is washing hair every other day with keto bad?

      in Chat  7 upvotes 1 year ago
      Using ketoconazole shampoo for seborrheic dermatitis is generally fine, but opinions vary on frequency, with some suggesting every other day and others less often. Proper scalp cleaning is emphasized to prevent itching and burning.

      community Seb derm is eating my hair?!?!

      in Chat  41 upvotes 2 years ago
      A 22-year-old male is experiencing hair loss due to seborrheic dermatitis, not male pattern baldness, and is seeking advice. Suggestions include using Nizoral, sulfate-free and ketoconazole shampoos, cutting hair short, using cold water, avoiding picking scabs, and trying selenium sulfide shampoo or finasteride.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Anyone here actually do topical cetirizine?

      in Question  4 upvotes 8 years ago
      The conversation discusses using topical cetirizine for hair loss and questions its effectiveness and preparation. A user expresses interest in trying it if it can be dissolved in minoxidil.

      community BREEZULA COVID UPDATE: Filing for Special Protocol Assessment with FDA

      in Research/Science  63 upvotes 5 years ago
      The conversation discusses the progress of Clascoterone (Breezula) for hair loss treatment, noting that COVID-19 delayed female trials by three months but Phase III trials for males are proceeding with a Special Protocol Assessment filed with the FDA. Users express hope for Breezula as an alternative to existing treatments like finasteride and minoxidil, despite concerns about its potential high cost.

      community Is it normal that fin tingles in the mouth?

      in Finasteride  59 upvotes 11 months ago
      A user experienced a tingling sensation in their mouth after taking a cut finasteride pill, possibly due to inactive ingredients like mannitol or sodium lauryl sulfate. Tingling is not a common side effect or typical allergy sign, but monitoring for unusual reactions is advised.

      community Has anyone experienced burning scalp after chemical damage (perm)?

      in Chat  6 upvotes 6 months ago
      A user experienced burning, itching, and soreness on their scalp after a perm in 2021, despite using oral finasteride, oral minoxidil, and ketoconazole shampoo. They are seeking advice on whether to pursue further medical tests or consult a neurologist for nerve pain.

      community hello

       148 upvotes 7 years ago
      A 12-year-old diagnosed with alopecia shares their experience and current treatments, including Dermovate, an unnamed cream, and liquid iron. The community offers support and encouragement.

      community Oral Minoxidil in Europe (10 mg)

      in Minoxidil  9 upvotes 1 year ago
      The user is seeking oral Minoxidil in Europe due to issues with topical Minoxidil causing dandruff and dry scalp. They have started using oral Finasteride and are considering Ketoconazole shampoo.

      community Anyone used CB-03-01 (clascoterone), is it worth it, too risky??

      in Research/Science  2 upvotes 1 year ago
      The user experienced side effects from low-dose topical finasteride and is considering using clascoterone (CB-03-01) despite concerns about its risks and cost. They seek advice on its effectiveness and potential side effects compared to other treatments like alfatradiol and fluridil.

      community Hairloss and dandruff.. potential sebderm inflammation?

      in Research/Science  1 upvotes 1 year ago
      A 21-year-old is experiencing aggressive hair loss and dandruff, possibly due to seborrheic dermatitis, and is using pumpkin seed oil, scalp massages, and anti-dandruff shampoo as treatments. They are hesitant to use prescribed Finasteride and Minoxidil and have noticed some improvement after stopping Serenoa capsules.

      community Carrier for homemade topical Finasteride

      in Chat  4 upvotes 1 year ago
      The conversation is about making topical finasteride using stemoxydine as a carrier. The user is considering buying Redken Cerafill Hair Re-Densifying Treatment (Stemoxydine) 90ml for this purpose.