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PP405 is a potential hair loss treatment that inhibits mitochondrial pyruvate carriers, increasing lactate dehydrogenase activity and stimulating hair follicle stem cells. In a phase 1 trial, 31% of participants showed over 20% hair density increase with PP405 treatment.

The post is about a user starting a hair loss treatment using finasteride, micro needling, and nizoral. The conversation includes supportive replies from other users.

The conversation is about using Maxogen-X for hair loss, which contains Minoxidil, Finasteride, Azelaic Acid, ABN Complex, Retinoic Acid, Fluocinolone, and Caffeine. The user is seeking feedback on its effectiveness.

The user has been using finasteride, minoxidil, and ketoconazole for hair loss, showing good progress without significant side effects. They plan to have a hair transplant in March and hope to eventually stop using oral minoxidil.

The user experienced hair loss issues after switching from finasteride to dutasteride and back, with stress and seborrheic dermatitis affecting hair quality. They plan to continue finasteride, treat seborrheic dermatitis, and monitor nutrient levels, considering low-dose oral minoxidil if safe.

The user has been using 1mg Finasteride and 5% topical Minoxidil for 9 months with little improvement and is now switching to 5mg oral Minoxidil, continuing microneedling, and adding Anagenil Complex. They are seeking advice on whether to stop topical Minoxidil and the effectiveness of Anagenil Complex.

The user is using finasteride 1mg daily for one month and ketoconazole three times a week for three months. They are comparing hair progress with photos from December 2025 and March 2026.

The conversation discusses switching from oral to topical finasteride due to side effects like nipple soreness. The user seeks advice on diluting and applying topical finasteride to minimize adverse effects.

The user noticed slight hair loss after switching to Milpharm finasteride and is considering switching to Accord finasteride. They seek advice on whether to continue with Milpharm or switch brands.

The conversation discusses Kevin's accurate information on hair loss treatments and highlights Dr. Bloxham's ongoing work with Verteporfin on FUT scars, suggesting people follow Dr. Bloxham's YouTube for updates. It also thanks Haicafe and Melvin from the hair restoration network forum for their contributions.

The user reported positive feedback on hair appearance after switching from topical to oral minoxidil and finasteride, with no side effects. The treatment includes 1.1mg finasteride, 3mg minoxidil, biotin, and vitamins B5, B6, and C daily.

The user underwent a DHI hair transplant with 3,066 grafts at Hairtec in the Netherlands and is using finasteride and minoxidil to restore hair, particularly at the crown. They plan to adjust minoxidil dosage and consult with a dermatologist in September.

Pyrilutamide (KX826) sourcing and pricing, with users discussing the legitimacy and cost of grey market versus official sources. The conversation highlights the high cost of official products and the effectiveness of grey market versions.

The user switched from finasteride to 2.5 mg dutasteride daily and added 1% pyrilutamide to address persistent scalp itch, but the itch remains. They also use 2% ketoconazole and 2.5% selenium sulfide shampoo for temporary relief.

User seeks participants for Verteporfin group buy. Verteporfin, FDA approved, may regenerate hair follicles and sweat glands through heavy microneedling.

The conversation is about DIY Dutasteride mesotherapy for hair loss, focusing on creating an injectable treatment to target the scalp and limit side effects. The user seeks feedback on enhancing the treatment with additional ingredients.

The user is struggling to find a reliable source to buy Kirkland Minoxidil in Canada, expressing concerns about the legitimacy of online sellers. They mention skepticism about websites like Kirkland Minoxidil Solution and Zecoya.

The conversation discusses an interview with Dr. Tsuji about hair follicle stem cell multiplication and the financial challenges of starting human clinical trials. It also mentions the need for funding to secure a patent for a protein that promotes hair growth.

A Phase II clinical trial for TDM-105795 has started recruiting in the US, and it might be a promising treatment for hair loss. Many hair loss drugs, including this one, originate from China.

The user is using ketoconazole shampoo, organic vinegar, iced aloe vera gel, and sulfur soap to address hair loss, avoiding minoxidil and finasteride unless necessary. Some users see improvement, while others suggest adding finasteride for better results.

A user is concerned about hair loss in the temple area despite using Minoxidil and finasteride for 10 months and is curious if PP405 can help. Responses indicate uncertainty about PP405's effectiveness, with some optimism about future treatments and AI speeding up drug discovery, but emphasize waiting for clinical trial results.

The user is using dutasteride and minoxidil for hair loss and noticed new hair growth after initially thinking there was no progress. Encouragement was given to continue the treatment as it takes time to see full results.

The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

The user has been using oral finasteride and minoxidil for hair loss but is considering switching back to topical minoxidil due to persistent scalp issues. Another user suggests an anti-inflammation regimen and oral dutasteride.

A 34-year-old underwent a hair transplant with 5,250 grafts, stem cell therapy, and PRP at Dr. Hakan Clinic in Istanbul, without using Minoxidil or Finasteride. Despite initial concerns about the hairline design, the user is optimistic about the results and plans to update progress over time.

SCUBE3 is available online but poses risks like tumor promotion and high costs. Users advise against using it due to health concerns and inefficacy as a standalone treatment.

A user praised Kevin Mann for his hair loss advice, crediting finasteride and minoxidil with tretinoin for saving their hair. Other users shared similar experiences and expressed frustration over Mann's channel being affected by past controversies.

A Swiss product called Redensyl, which is supposed to target hair follicle stem cells and has recently been marketed in Europe. The post inquires if anyone has had any experience with the product.

The user successfully improved their hair from Norwood 3 to 0.5 using finasteride, topical minoxidil, microneedling, and a hair peptide, and plans to maintain it with dutasteride. They are leaving the forum due to emotional distress caused by the community.

A 23-year-old male had a hair transplant with 3500 grafts and is using finasteride, minoxidil, hair vitamins, and a keto shampoo. He seeks advice on crown regrowth and when to start dermastamping.