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      community Why is there more skepticism in RU than Pyrilutamide?

      in Chat  12 upvotes 3 years ago
      The conversation is about skepticism towards the hair loss treatments RU58841 and Pyrilutamide, with users discussing the lack of human testing for RU58841 and the ongoing trials for Pyrilutamide. Some users believe RU58841 has more anecdotal success, while others highlight Pyrilutamide's current research progress.

      community Why is nobody talking about topical Spironolactone?

      in Chat  7 upvotes 6 days ago
      Topical spironolactone is discussed as a hair loss treatment, with concerns about its effectiveness and side effects compared to finasteride and minoxidil. Users mention its unpleasant smell, potential systemic absorption, and suggest alternatives like pyrilutamide and alfatradiol.

      community Has anyone experimented with Finnestride 1mg/daily and Dutastride topically?

      in Treatment  3 upvotes 1 year ago
      A user on finasteride for hair loss is considering topical dutasteride to further reduce scalp DHT and is using various other topicals as substitutes for minoxidil due to concerns about the safety of their cats and potential heart side effects from oral minoxidil. They are exploring whether a once-weekly application of topical dutasteride would be effective.

      community Second shed, non-stop flaking, itching

      in Treatment  12 upvotes 1 year ago
      The user is experiencing a second hair shedding phase and increased flaking and itching while using minoxidil 5% nightly and microneedling every two weeks, with needle length increasing over time. Other users suggest the hair loss may continue without the use of finasteride.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community PROGRESS ON NEW ROUTINE - DUT/Minox/Microneedling

      in Progress Pictures  6 upvotes 5 months ago
      The conversation is about a user's hair loss treatment progress using a routine of Avodart (Dutasteride), oral and topical Minoxidil, Ketoconazole shampoo, and microneedling. The user reports no side effects and shows improvement after resuming consistent treatment.

      community Problem with Topican Finasteride, sides

      in General  119 upvotes 4 months ago
      The user experienced side effects like shallow breathing, loss of libido, and erectile issues after using topical finasteride with minoxidil for hair loss. They are considering whether to continue the treatment despite these side effects.

      community KX-826 1% Phase II Results from China Just Dropped

      in Research/Science  36 upvotes 8 months ago
      KX-826 (Pyrilutamide) 0.5% and 1.0% solutions showed promising results in increasing hair count for male androgenetic alopecia, with the 0.5% dose slightly outperforming the 1% dose. The treatment was well-tolerated with no sexual side effects, but skepticism remains due to past inconsistencies in trial results.

      community Daily keto and twice daily topical fin/mix. Too much?

      in Treatment  6 upvotes 2 years ago
      DutchFella1993 has been using a lotion with finasteride and minoxidil for hair regrowth with some success and is considering using ketoconazole shampoo daily to reduce scalp itchiness. There's concern about the harshness of daily shampooing and twice-daily lotion application, and one reply suggests that daily use of ketoconazole may damage hair and questions its effectiveness, while also noting that once-daily minoxidil application is sufficient.

      community Is there a possibility it's only because of the SD

      in Ketoconazole 4 years ago
      A user is experiencing severe hair loss, diagnosed with seborrheic dermatitis, and is using Ketoconazole and beclomethasone. They are concerned about potential female pattern baldness and are seeking reassurance and advice.

      community What dosage topical Finasteride should I go with?

      in Chat 8 months ago
      The conversation is about adjusting the dosage of topical Finasteride to avoid side effects like chest pain and breast swelling. The user is considering reducing the concentration to 0.1% or trying microdosing with 0.01-0.025% for lower systemic effects.

      community Pyrilutamide: hairloss continues

      in Treatment  12 upvotes 3 years ago
      The conversation is about someone experiencing continued hair loss despite using Pyrilutamide and considering the need for more time or better quality control for the treatment. Another person suggests waiting for the drug to be officially approved due to potential quality issues with current products.

      community Alfatradiol 1% study rebuttal.

      in Research/Science  4 upvotes 2 years ago
      Alfatradiol is often discussed at a 1% concentration, but studies typically use 0.025%. Some users report success using it as a topical treatment alongside other hair loss treatments like finasteride.

      community So... any chinese suppliers for real pyri?

      in Research/Science  5 upvotes 1 year ago
      The conversation discusses sourcing pyrilutamide from China for hair loss treatment, highlighting its potency compared to other AR antagonists like bicalutamide and RU58841. The user expresses interest in trying pyrilutamide despite mixed results in clinical trials.

      community Is this solution unnecessarily aggresive?

      in Product  2 upvotes 3 months ago
      The solution contains minoxidil, finasteride, azelaic acid, caffeine, retinoic acid, and procapil. Users suggest minoxidil with tretinoin and a 5-alpha reductase inhibitor, while dismissing retinoic and azelaic acids as unnecessary.

      community Setipiprant/PGE2 feedbacks?

      in Question  4 upvotes 7 years ago
      The conversation discusses using PGE2 as a hair growth stimulant, comparing it to minoxidil, and considering the addition of Setipiprant. Concerns about side effects like skin damage and cost are also mentioned.

      community Caffeine after dermarolling: Do or don't?

      in Treatment  3 upvotes 10 months ago
      Caffeine use after dermarolling is debated, with some users reporting positive effects on hair shedding and growth. One user recommends caffeine for reducing hair shedding and enhancing hair growth, while another is skeptical of its benefits.

      community dut/min /copper peptides VS PP405 results

      in Technology  1 upvotes 2 weeks ago
      Minoxidil, dutasteride, and copper peptides are used in a tattooing method for hair regrowth, with some users noting better results compared to oral treatments. Copper peptides are considered to have minimal impact, but the method may reduce side effects.

      community Wednesday after micro needling through Friday today.

      in Treatment  1 upvotes 1 year ago
      The user is using oral and topical minoxidil, finasteride, dutasteride, and considering adding rosemary and pumpkin saw palmetto to their regimen. They report significant hair growth, especially with dutasteride, and are considering increasing their dose and adding RU58841.