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      community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

       23 upvotes 6 years ago
      A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

      community Using topical vitamin D, does it make sense?

      in Chat  6 upvotes 3 years ago
      Topical Calcipotriol (vitamin D derivative) may help with hair regrowth, especially for alopecia areata. The user wonders if adding classic vitamin D to lotions like Minoxidil could have a similar effect.

      community tretinoin cream concentration question

      in Treatment  12 upvotes 3 years ago
      The conversation is about choosing the right concentration of tretinoin cream to enhance the absorption of minoxidil for hair loss treatment. The options discussed are 0.5, 0.05, 0.25, and 1mg/g concentrations.

      community Topical solution recommendation

      in Product  1 upvotes 8 months ago
      The user is using finasteride 1mg every other day and seeks a topical solution to complement it, excluding minoxidil. They are considering various combinations of ingredients like finasteride, dutasteride, and tofacitinib, with options for nourishing oils and other additives.

      community 5 months progress post on topical min and fin

      in Is this regrowth?  27 upvotes 1 year ago
      User shared a 5-month progress update on using topical minoxidil 6% and finasteride 0.05% once daily, with microneedling and vitamins. They experienced initial shedding but no side effects, and increased the treatment to twice daily after month 4.

      community Peak efficacy ($18 for a 4 month supply)

      in Minoxidil  14 upvotes 1 year ago
      The conversation discusses a hair loss treatment regimen involving a homemade topical solution of Minoxidil and Tretinoin, combined with Finasteride and microneedling. Users share advice on Tretinoin application, emphasizing gradual use to avoid skin irritation.

      community Microneedling versus Platelet-Rich Plasma

      in Research/Science  9 upvotes 6 months ago
      Microneedling and Platelet-Rich Plasma (PRP) are equally effective for treating androgenetic alopecia, with no additional benefits from PRP over microneedling. Both treatments are safe and well-tolerated.

      community Dermaroller vs dermastamp vs dermapen

      in Microneedling  5 upvotes 1 year ago
      Microneedling is debated for hair loss treatment, with some users finding it beneficial for minoxidil absorption and others skeptical of its effectiveness. Alternatives like finasteride and minoxidil are recommended, while tools like dermarollers, dermapens, and dermastamps are discussed for their pros and cons.

      community Min/Fin topical prescription also contains Latanoprost?

      in Treatment  3 upvotes 1 year ago
      A user discusses a topical prescription for hair regrowth containing Minoxidil, Finasteride, and Latanoprost, noting Latanoprost's side effect of promoting eyelash and eyebrow growth. Others share experiences and information about Latanoprost, highlighting its origins as a glaucoma drug and potential side effects.

      community 2.5% topical fin too high?

      in General  53 upvotes 10 months ago
      The conversation discusses starting topical finasteride for hair loss, with concerns about high dosages. It suggests starting with a lower concentration, like 0.1% or 0.3%, especially with liposomal versions.
      Trying to identify area of treatment with topical fin

      community Trying to identify area of treatment with topical fin

      in General  136 upvotes 4 months ago
      The user is considering using topical finasteride for thinning hair around the middle part, vertex, and crown, and is unsure if the whole scalp is thinning. Another user suggests oral finasteride is more effective than topical, and recommends consulting a dermatologist for proper treatment.

      community Combining daily microneedling and redlight is a game changer

      in Microneedling  22 upvotes 1 year ago
      The conversation discusses using daily microneedling at 0.25mm and red light therapy to enhance hair regrowth, especially when traditional treatments like finasteride and minoxidil become less effective. The combination is said to improve hair density and thickness, with red light therapy being more cosmetic, while microneedling is essential for challenging areas.

      community five months dermaroller on penis

      in Satire  539 upvotes 2 years ago
      The conversation is a satirical discussion about using a dermaroller on the penis, with mentions of adding finasteride and doing exercises like cock pushups and planks. Some users joke about side effects and the absurdity of the topic.

      community 4 month Min+Fin progress (topical)

      in Progress Pictures  124 upvotes 1 year ago
      A user shared their 4-month progress using a topical solution with 5% minoxidil and 0.1% finasteride, applied twice daily. They reported good results despite occasional missed applications.

      community PP405 Effectiveness in Transplant Area?

      in Transplants  3 upvotes 3 months ago
      Hair transplant recipients are concerned about whether dormant follicles are permanently damaged by incisions, but some believe undamaged follicles could still regrow if a treatment like PP405 is effective. Opinions vary on the impact of transplants on original follicles, with some suggesting treatments like finasteride can help regrow hair.

      community What happened to topical dutasteride??

      in Finasteride/Dutasteride  28 upvotes 1 year ago
      Topical dutasteride is considered for hair loss, but concerns about systemic absorption and side effects like reduced libido are common. Users have mixed results, with some preferring oral finasteride or dutasteride despite side effects, while others find topical treatments beneficial but challenging.

      community Any anecdotes about tretinoin and min?

      in Minoxidil  7 upvotes 1 year ago
      The conversation discusses the effectiveness of combining tretinoin with minoxidil for hair loss. The user notes better results from microneedling rather than the tretinoin and minoxidil combo.

      community 20M, 2.5 months, 1mg fin, topical min(local)

      in Progress Pictures  127 upvotes 11 months ago
      A 20-year-old male shares his 2.5-month progress using 1mg finasteride, topical minoxidil, tretinoin, dermarolling, and ketoconazole for hair loss, noting slight libido decrease. Users discuss sourcing topical finasteride and request more photos to see the results.

      community Best brand of topical melatonin?

      in Product  8 upvotes 3 years ago
      People are using topical melatonin for diffuse thinning and retrograde alopecia. They are discussing the best brands and application methods.

      community Topical minoxidil and salicylic acid

      in Minoxidil  4 upvotes 1 year ago
      The user has been using finasteride for 6 months with decent results and recently added topical minoxidil. They are concerned that salicylic acid in their skincare products might reduce minoxidil's effectiveness.

      community Dutasteride mesotherapy where to buy

      in Finasteride/Dutasteride  3 upvotes 5 months ago
      The conversation is about purchasing dutasteride solution for mesotherapy, with a suggestion to make it using dutasteride capsules and oils. A user shared a link to a potential supplier and mentioned using dutasteride with microneedling.