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A user is seeking advice on the efficacy and side effects of homemade topical solutions for hair loss, specifically bicalutamide, estradiol, cyproterone acetate, and spironolactone, as they cannot access RU58841 or pyrilutamide.

The user reports that using topical Dutasteride has stopped their hair loss, and they are curious about potential side effects and regrowth. They also mention having scalp psoriasis and past SSRI use affecting libido.

A user shared their positive experience with a 4-in-1 topical solution containing finasteride, minoxidil, ketoconazole, and biotin, along with weekly microneedling using a 1.2mm dermastamp. The user reported no noticeable side effects and mentioned that the biotin likely doesn't contribute to hair growth.

The reduction in scalp oiliness is likely due to finasteride reducing DHT levels and the use of ketoconazole shampoo. The combination of these treatments may have decreased sebum production.

A woman with hair loss discovered she has thyroid cancer, which was found during an MRI and confirmed with an ultrasound. She advises others with symptoms to see a doctor and shares that her cancer was detected after her dog sniffed her neck and she experienced neck pain.

The user experienced significant hair regrowth with topical finasteride, minoxidil, ketoconazole, and dermarolling, but later faced severe hair shedding after stopping dermarolling and reducing ketoconazole use. Suggestions included switching to oral treatments, resuming dermarolling, and considering lifestyle changes.

The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.

A 25-year-old male using Dutasteride, oral Minoxidil, and Ketoconazole shampoo is experiencing increased hair shedding and vellus hair growth along the hairline. Concerns are raised about whether this is a seasonal shed or a potential setback.

A 25-year-old is experiencing chronic telogen effluvium (TE) and androgenetic alopecia (AGA) after surgery, using finasteride, red light therapy, and supplements, and considering oral minoxidil despite heart concerns. They are unsure whether to start minoxidil before or after an upcoming surgery, which may trigger another hair shed.

Topical bicalutamide is discussed as a potential hair loss treatment. Other treatments mentioned include Minoxidil, finasteride, and RU58841.

The conversation is about a person considering participating in a study for Clascoterone, a topical cream for hair loss, and seeking advice on potential side effects. They have mild hair loss and are not currently using other treatments like finasteride.

A potential non-invasive topical treatment targeting the WNT Signaling Pathway for hair regeneration is being researched, with positive results on human hair follicle cells. Current effective treatments for hair loss include Minoxidil, finasteride, and hair transplantation.

A user experienced skin irritation and acne while using Minoxidil foam, but after stopping both the foam and a sea salt spray, their skin improved. They plan to try oral Minoxidil, suspecting the sea salt spray, not Minoxidil, was the main cause of their skin issues.

A 27-year-old has seen hair regrowth over 5 months using 2ml of 5% minoxidil daily, 50mg of RU58841 daily, and occasional microneedling. Commenters think the results are good and ask about microneedling frequency, needle size, and if ketoconazole shampoo is used.

KX-826 hair loss treatment completed trials with mild side effects. GT20029 may be ultimate cure, destroying androgen receptors causing baldness.

Using tretinoin with minoxidil can cause burning and flaky skin due to alcohol in minoxidil and tretinoin's effects. Solutions include using minoxidil foam, starting with low tretinoin doses, moisturizing, and gradually increasing usage.

A user shared their hair loss journey, detailing their use of Kirkland Minoxidil 5%, finasteride, dutasteride, and weekly dermarolling. They experienced initial success with minoxidil but faced setbacks with oral minoxidil and are now back on topical treatments.

Quercetin reduced scalp soreness and may help with histamine-related hair loss. The soreness felt like inflamed follicles beneath the scalp surface.

People are discussing the use of the peptide GHK-Cu for hair and skin, with mixed results. Some users have tried it alongside other treatments like adenosine and melatonin, but have not seen significant improvements, and one user stopped due to cost.

The conversation discusses topical androgen receptor blockers for hair loss, mentioning Clascoterone, Pyrilutamide, GT20029, and RU58841. Ketoconazole's effectiveness and application methods are also debated.

Topical tretinoin applied to the face may exacerbate hair loss in some individuals, potentially triggering conditions like frontal fibrosing alopecia. Experiences vary, with some users reporting no impact on hair, while others experience significant hair loss.

The user started using topical and oral Minoxidil in December 2024, added ketoconazole shampoo in February 2025, and began using topical Dutasteride mixed with Minoxidil. The ketoconazole shampoo stopped scalp itchiness, but the hairline looks the same, with existing hairs appearing frail and thin.

User started minoxidil, noticed forehead lines and dark circles, and asked for non-invasive skin aging prevention methods. Another user suggested using tretinoin and hyaluronic acid for long-term benefits.

A 21-year-old is experiencing aggressive hair loss and dandruff, possibly due to seborrheic dermatitis, and is using pumpkin seed oil, scalp massages, and anti-dandruff shampoo as treatments. They are hesitant to use prescribed Finasteride and Minoxidil and have noticed some improvement after stopping Serenoa capsules.

A 29-year-old male shares progress pictures after 4 months using finasteride and 2% ketoconazole shampoo, noting initial shedding but overall improvement. He avoids minoxidil and microneedling, and reports thicker hair in balding areas while maintaining high water intake.

The post and conversation discuss different methods of applying hair loss treatments directly to the scalp. The original poster suggests using a 1ml TB Syringe & Ophthalmic Cannula for precise application, while others share their own methods, including sprays, droppers, and simple syringes.

The user is considering RU58841 and has been using dutasteride since age 17. They are seeking affordable SARD options, mentioning ASC-J9, GT20029, and AH001.

Excess Vitamin A and topical retinoids can cause diffuse hair shedding. The user suspects their chronic telogen effluvium may be linked to using adapalene, a topical retinoid.

User tried dutasteride, topical finasteride, oral minox, dermawounding, saw palmetto, pumpkin seed oil, and ketacozonole for hair loss. Improvement was temporary, now trying RU58841 and seeking help.

DutchFella1993 has been using a lotion with finasteride and minoxidil for hair regrowth with some success and is considering using ketoconazole shampoo daily to reduce scalp itchiness. There's concern about the harshness of daily shampooing and twice-daily lotion application, and one reply suggests that daily use of ketoconazole may damage hair and questions its effectiveness, while also noting that once-daily minoxidil application is sufficient.