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community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

in Research/Science 127 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community Can selenium be harmful to hair?

in Product 5 upvotes 3 years ago

The user experienced increased hair shedding after taking a multivitamin containing selenium and questioned if selenium was the cause. The conversation revolves around the potential negative effects of selenium on hair health.

community Well, I guess this puts the scalp tension theory to bed

in Satire 138 upvotes 4 years ago

Hair loss discussion includes various causes like DHT, blood flow, and skin fibrosis. Treatments mentioned are Minoxidil, Finasteride, and RU58841.

community Am i a hyper responsive ? Why i see results on areas i don’t put products in?

in Is this regrowth? 489 upvotes 3 months ago

The user saw significant hair regrowth using topical minoxidil and finasteride, even on areas not directly treated. They used local Algerian products with 5% minoxidil and 0.1% finasteride and reported no side effects.

community Topical finasteride might be a lie

in Research/Science 2 years ago

The conversation discusses doubts about the effectiveness of topical finasteride for hair loss, suggesting that DHT could be produced elsewhere in the body and affect the scalp. It proposes that androgen receptor antagonists like spironolactone and clascoterone might be more effective as they could prevent this potential bypass mechanism.

community Studies or evidence for concentration for topicals?

in Research/Science 1 upvotes 1 year ago

The conversation discusses using different concentrations of topical treatments for hair loss, specifically Minoxidil, Finasteride, Dutasteride, and Tretinoin. The user is considering higher concentrations after previous treatments were ineffective.

community Laser Diode Cap, I already use Oral Fin, Topical Min 5%, Nizoral and Microneedling

in Treatment 1 upvotes 6 months ago

The user is seeking advice on maximizing hair growth while using oral finasteride, topical minoxidil, Nizoral, and microneedling, and is considering adding a laser diode cap, topical finasteride, retinol, and caffeine. Suggestions include using tretinoin with minoxidil for better absorption, switching to dutasteride, and considering RU58841 or pyrilutamide.

community So whats the consensus for Microneedling Routines?

in Microneedling 7 upvotes 1 year ago

Optimal microneedling routine is 1.25mm once a week with Dr Pen 36 needles. Applying Minoxidil right after microneedling may increase systemic absorption risk.

community Alfatradiol causing shedding ?

in Treatment 1 upvotes 1 year ago

The user experienced a sudden decrease in hair density after starting alfatradiol while already using finasteride. Another user mentioned that initial shedding can occur with hair loss treatments, but it may not last long.

community Anti-androgen use causing testicular pain?

in Finasteride/Dutasteride 5 upvotes 9 months ago

Switching from topical finasteride to oral Dutasteride and using Fluridil caused persistent testicular discomfort. The discomfort did not subside after stopping Fluridil, raising concerns about Dutasteride's role.

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