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      community Follicum releases some data from previous phase 2a trial

      in Research/Science  13 upvotes 2 years ago
      Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

      community Treating my DUPA via controlling inflammation

      in Treatment  4 upvotes 2 years ago
      The user has DUPA and suspects autoimmune activity as a cause. They have tried various treatments including finasteride, minoxidil, dutasteride, pyrilutamide, estrogel, hydrocortisone, and clobetasol, and are now seeking a long-term immunosuppressant.

      community Looking for the new RU58841 source in EU

      in Treatment  6 upvotes 2 years ago
      A user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and are using a treatment mixing RU58841 with Stemoxydine and Alfatradiol.

      community Looking for the new RU58841 source in EU

      in Treatment  5 upvotes 2 years ago
      A user is seeking a new source for RU58841 in the EU after their previous supplier stopped selling it. They mention considering Anagen, Actifolic, Minoxidilmax, and rudirect, and are using a treatment mixing RU58841 with Stemoxydine and Alfatradiol.

      community How to take care of the microneedler?

      in Microneedling  7 upvotes 7 months ago
      Disinfecting microneedlers is important to prevent infection, with suggestions to use high-percentage alcohol or denture tablets for sterilization. Rollers may cause skin damage, so stamps or pens are recommended for safer microneedling.

      community The 'DHT itch' is real - notes from a casual bodybuilder

      in Chat  115 upvotes 1 year ago
      The "DHT itch" is real and likely due to inflammation at the hair follicle, exacerbated by increased testosterone or androgens. Treatments mentioned include dutasteride, minoxidil, finasteride, and various topical solutions.

      community Wednesday after micro needling through Friday today.

      in Treatment  1 upvotes 1 year ago
      The user is using oral and topical minoxidil, finasteride, dutasteride, and considering adding rosemary and pumpkin saw palmetto to their regimen. They report significant hair growth, especially with dutasteride, and are considering increasing their dose and adding RU58841.

      community Just started ru58841, ask me anything.

      in Research/Science  14 upvotes 2 months ago
      The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

      community Crystals in Minoxidil bottle

      in General  89 upvotes 11 months ago
      Minoxidil bottle developed crystals, possibly due to air exposure, but the trichologist advised not to worry. The user questions the advice, noting the lack of recommendations for finasteride or derma rolling.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

      in Treatment  7 upvotes 9 months ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community Do any shampoos contain Piroctone Olamine in the US

      in Product  3 upvotes 1 year ago
      The conversation is about finding shampoos with Piroctone Olamine in the US for itch relief, as the user has not found relief with Keto shampoo, oral Dutasteride, and oral Minoxidil. Users suggest alternatives like Neutrogena T/Gel and online options, but note availability and price issues.

      community Any scalp-friendly min+ru products available in UK?

      in Product  1 upvotes 6 months ago
      The user is seeking recommendations for scalp-friendly minoxidil and RU58841 products available in the UK, as previous products caused scalp inflammation. They mention issues with RUDirect and MinoxidilMax products.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community KX-826 Pyrilutamide1% coming soon

      in Update  152 upvotes 1 year ago
      KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

      community Malabsorption: Nutrient Testing and Supplementation

      in Treatment  2 upvotes 1 year ago
      The user is experiencing severe hair loss due to gut malabsorption and is seeking advice on nutrient testing and supplementation. They have low Vitamin D and Ferritin levels and are asking for recommendations on additional nutrients and blood tests to consider.

      community Anyone ever get a shedding phase on RU58441

      in Chat  6 upvotes 1 year ago
      The user experienced increased hair shedding after using RU58841 for two months, but found relief from scalp itchiness. Other users shared similar shedding experiences and discussed side effects like joint pain, while also mentioning the use of finasteride and minoxidil.

      community Actifolic RU58841 with octopirox?

      in Treatment  1 upvotes 4 years ago
      The conversation discusses using RU58841 with octopirox or essential oils for hair loss treatment. The user is seeking advice on which variation to try.

      community Cosmo Pharma Lists Breezula Phase 3 Trial on ClinicalTrials.gov

      in Research/Science  24 upvotes 2 years ago
      A phase 3 trial for Breezula (clascoterone solution) to treat male pattern hair loss has been listed, with 726 participants and a completion date of January 2025. Other treatments mentioned include Aneira Pharma's combination of minoxidil and latanoprost, Triple Hair's combination of minoxidil, latanoprost, and finasteride, and a new microneedling and LLLT device called StimuSIL.

      community MinoxidilMax just launched a 0.3% tretinoin topical. Would you try?

      in Treatment  14 upvotes 4 years ago
      The conversation discusses a new 0.3% tretinoin topical launched by MinoxidilMax for mixing with other solutions, with some users expressing concern about potential skin irritation compared to lower concentrations. MinoxidilMax has also released other products like topical Dutasteride and RU58841.