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360-390 / 1000+ resultscommunity Pyrilutamide available at Actifolic now
Pyrilutamide, a new hair loss product with the potential to be more effective than RU58841 and safer than CB, but expensive.
community Creating an all-in one topical. Dumb idea?
The user is considering combining finasteride and minoxidil tablets into a topical solution that already includes Garnier Fructis stemoxydine and CB0103. They are seeking advice on whether this combination is effective and safe.
community Haunting study is making me considering cycling fin/dut
Concerns about the long-term effects of dutasteride and finasteride on fertility, with discussions on cycling these medications to mitigate risks. The conversation highlights skepticism about study methodologies and the importance of weighing treatment risks against potential fertility issues.
community Has anyone tried CB-01-03 aka Clascoterone?
Clascoterone, a topical anti-androgen, is generating interest for potentially fewer systemic side effects. Users are curious about its effectiveness and details like concentration and duration of use.
community Different Topical Dutasteride Formulations
The conversation discusses the best vehicle for topical dutasteride, comparing Trichosol, Transcutol, and a gel version. It also mentions using Transcutol with ethanol to enhance transdermal delivery of Bimatoprost.
community Recent progress on stack including third verteporfin procedure
community 20M NW6 diffuse —> NW1 Fin/Dut
A user shared progress pictures showing improvement from NW6 diffuse to NW1 after 5 months of finasteride and 2 months of dutasteride. Another user asked if these treatments affected beard or body hair thickness.
community Those who tried compounded clascoterone how was your results.
community How to use thickening hair products?
User asks for advice on using hair thickening products and their order of application. Experienced styler suggests using thickening tonic with a blow dryer, followed by styling powder and clay, then hair fibers, and finishing with hairspray.
community pyrilutamide - did anybody had any success on it?
Potential success with the hair loss treatment Pyrilutamide, and possible group buying opportunities for it along with other treatments such as Finasteride and Minoxidil.
community Temples after a month
The conversation discusses hair loss treatments, specifically using Minoxidil, finasteride, and RU58841. The focus is on progress observed at the temples after one month of treatment.
community Despite its straightforward mrchanism of action, it looks like pyrilitamide doesn't help regrow hair like finasteride does.
Pyrilitamide (KX-826) did not show significant improvement in hair count compared to placebo after 6 months. It's unclear if it can maintain hair at baseline.
community How am I doing with temple regrowth?
A 25-year-old male is experiencing positive temple regrowth after using 1 mg oral finasteride daily and a custom topical solution from Musely containing minoxidil, dutasteride, tretinoin, ketoconazole, and hydrocortisone. He is considering adding dermarolling to enhance results, while others share their experiences and suggestions for hair regrowth treatments.
community Korean scientists breakthrough in hair regeneration targeting CXXC5 protein and WNT Signaling Pathway
A potential non-invasive topical treatment targeting the WNT Signaling Pathway for hair regeneration is being researched, with positive results on human hair follicle cells. Current effective treatments for hair loss include Minoxidil, finasteride, and hair transplantation.
community Breezula disappearing like my hair follicles.
Breezula's development has stalled, leaving users disappointed. The conversation includes skepticism about its approval and effectiveness.
community Why only the top of the head?!
Why the top of the head is affected by hair loss more than other areas, and treatments such as surgery, medications like minoxidil, finasteride, and RU58841 to treat it.
community Forgotten 'Total Revival' Stack
Cyclosporine A is discussed as a powerful hair growth stimulant, potentially more effective than minoxidil, but concerns about safety and side effects, including cancer risk, limit its use. The conversation highlights the need for further research and experimentation with topical application, despite its risks.
community Diffuse thinning is the worst man
The conversation is about the struggles of dealing with diffuse thinning at a young age and the lack of significant improvement after using treatments like finasteride and minoxidil. Some suggest additional methods like derma rolling, microneedling, and hair fibers, while others share their own experiences and encourage persistence with treatment.
community FCE 28260: A Forgotten 5α-Reductase Inhibitor
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community Thinking about my making own CB-03-01 (Breezula). Thoughts?
The user experienced side effects with both oral and topical finasteride and is considering making their own hair loss treatment using CB-03-01 (Breezula) mixed with minoxidil due to fewer reported side effects. They plan to use a lower concentration than what was used in trials.
community Is the Cecred line actually legit or are people lying to us?
Cecred hair drops, containing keratin and biotin, are questioned for their effectiveness compared to proven treatments like minoxidil. Users express skepticism, suggesting deceptive marketing and the possibility of undisclosed use of other treatments like finasteride.
community Why not move miniaturized hair follicles somewhere else to treat them? Alternative to hair cloning?
Exploring the idea of transplanting miniaturized hair follicles to healthier areas to potentially reverse hair loss, with concerns about DHT sensitivity and scar tissue formation. The conversation also humorously considers using mice for hair growth experiments.
community Clascoterone Scalp 2 Results in July?
community New baby hairs are popping out. Question though: what are these black dots on hairline? Clogged pores?
The user is experiencing new hair growth after using oral dutasteride, topical minoxidil, and microneedling, but is concerned about black dots on the hairline, which might be clogged pores or dormant follicles. The user previously used a topical minoxidil/finasteride spray and had good results, despite a shedding phase after switching treatments.
community Minoxidil, Fin and Cetirizine.
The user started a hair care routine using 0.5mg finasteride daily, 2ml of 5% minoxidil, and 4.5mg of cetirizine topically to address hair loss. They plan to provide updates and are also interested in cetirizine's potential to reduce scalp itching and redness due to its anti-inflammatory properties.
community Androgenic alopecia exclusively on the vertex of the scalp
A user experienced androgenic alopecia starting at the vertex without frontal hairline recession and is seeking information on this pattern. Another user noted that vertex or diffuse hair loss is common among men.
community is there a pyrilutamide group/discord to discuss results?
Discussing results, side effects and potential sources of pyrilutamide for hair loss treatment alongside RU58841 and other treatments such as Minoxidil and finasteride.
community Clascoterone might be the Finasteride for female pattern hair loss.
community Nuclear Stack Ineffective: Oral DUT/FIN/MIN/RU - NAFLD?
The user experienced severe hair shedding despite using oral finasteride, minoxidil, dutasteride, and RU58841, and was diagnosed with Non-Alcoholic Fatty Liver Disease (NAFLD). They are considering switching to topical treatments due to the ineffectiveness of their current regimen.