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      community Some among us are the chosen ones

      in Chat  122 upvotes 10 months ago
      Some individuals experience hair loss despite using treatments like 2.5 mg dutasteride, finasteride, and minoxidil, suggesting sensitivity to DHT or other factors. Various treatments and lifestyle changes are discussed, but results vary, and some consider hair transplants or other solutions.

      community Cmon Pyrilutamide and CosmeRNA 😭

      in Chat  36 upvotes 2 years ago
      Users discuss waiting for new hair loss treatments and share struggles with side effects from current options like Minoxidil and Finasteride. They express hope for Pyrilutamide and CosmeRNA to provide better solutions.

      community PYRILUTAMIDE progress in 15 months

      in Progress Pictures  25 upvotes 2 years ago
      The conversation discusses hair loss treatments, specifically the progress made with Pyrilutamide over 15 months. One person suggests using oral Minoxidil or Dutasteride, but another mentions experiencing negative side effects from oral Finasteride.

      community Hydrophobic Finasteride. Why don’t we have it?

      in Chat  6 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community Painkillers May Block Minoxidil

      in Research/Science  15 upvotes 1 year ago
      Painkillers like Aspirin may reduce Minoxidil's effectiveness by inhibiting the enzyme PGHS-1, which is crucial for hair growth. Using NSAIDs that inhibit COX-2 or combining Minoxidil with PGF2/E2 analogues or retinoids may enhance its efficacy.

      community Is finasteride just not working for me? test results

      in Finasteride/Dutasteride  3 upvotes 8 months ago
      A 21-year-old is experiencing aggressive hair loss and questions the effectiveness of finasteride after 45 days of use, with high DHT levels. A user advises that scalp DHT, not serum DHT, is important for hair loss assessment, and suggests monitoring hair improvement over time.

      community Carrier for homemade topical Finasteride

      in Chat  6 upvotes 1 year ago
      The conversation is about making topical finasteride using stemoxydine as a carrier. The user is considering buying Redken Cerafill Hair Re-Densifying Treatment (Stemoxydine) 90ml for this purpose.

      community Insane Idea: Cyperus Rotundus Oil?

      in Research/Science  9 upvotes 1 year ago
      Cyperus rotundus oil is suggested as a natural treatment for androgenic alopecia, potentially inhibiting hair growth without affecting testosterone levels. The conversation questions its effectiveness and safety for scalp use.

      community I want to attempt to use the MPC inhibitor JXL-069

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses skepticism about group buys for hair loss treatments, highlighting issues with unverified chemicals and the risks involved. It suggests stabilizing with dutasteride and minoxidil, and considering a hair transplant instead of experimenting with untested products.

      community Do we have to be junkies? That's funny

      in Research/Science  13 upvotes 1 year ago
      The conversation discusses using finasteride, dutasteride, minoxidil, cialis, and metformin to protect hair and health. Some users caution against self-prescribing these drugs due to potential risks and complications.

      community I wrote a poem about pp405 (potential treatment)

      in Satire  19 upvotes 1 year ago
      A poem humorously suggests hope for a new hair loss treatment, PP405, while users debate the effectiveness and side effects of current treatments like Finasteride. Concerns are raised about Finasteride's side effects, especially for young users, and skepticism about new treatments is expressed.

      community Hair Cafe vid: low dose dutasteride ?

      in Finasteride/Dutasteride  6 upvotes 1 year ago
      The user is considering using 0.5 mg dutasteride once every 5 or 7 days due to side effects from finasteride and is also looking into topical liposomal dutasteride and pyrilutamide to stop hair loss. The goal is to stop hair loss, not regrow hair.

      community day 107 of kx826 .5% . 1+ years on topical minoxidil.

      in Progress Pictures  18 upvotes 1 year ago
      The user has been using topical minoxidil for over a year and added kx826/pyrilutamide to improve hair growth, avoiding finasteride due to side effects like lowered libido and panic attacks. They report positive results with reduced shedding and healthier hair, particularly in areas previously unresponsive to minoxidil.

      community FDA approves Cassiopea's WINLEVI (CB-03-01, 1% formulation) for Acne

      in Technology  36 upvotes 5 years ago
      The conversation is about the FDA approval of WINLEVI for acne treatment and the anticipation of Breezula, a hair loss treatment using the same active ingredient, which may indicate a positive future for Breezula's release. There is disappointment that Breezula's results are not optimal, but it is seen as progress in hair loss treatment.

      community Are the japanese Finasteride 10 year studies even relevant to caucasian men - especially young ones?

      in Technology  109 upvotes 2 years ago
      The conversation is about the effectiveness of hair loss treatments, specifically finasteride and dutasteride, in different populations. Some users believe that the results of Japanese studies may not be relevant to Caucasian men, especially young ones, and that East Asians may respond better to these treatments. Others argue that clinical studies should be the basis for decision-making, while acknowledging that individual responses to medications can vary.

      community When could we expect pp405 to hit the market?

      in Research/Science  31 upvotes 11 months ago
      PP405 is expected to finish Phase 2 trials in late 2025, with potential market availability around 2028-2029 if all goes well. Current treatments like finasteride and minoxidil are still popular, while new options like KX-826 and Breezula are anticipated soon.

      community RU-58441 Janoshik test result of Made-In-China Supplier

      in Product  27 upvotes 4 months ago
      A user ordered RU58841 from a Chinese supplier, found it to be less than 99% pure, and plans to try a different seller next time. Concerns were raised about impurities, but the user believes they are likely inactive fillers rather than harmful substances.