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      community KX-826 , a small change in the pipeline

      in Research/Science  6 upvotes 2 months ago
      KX-826 is undergoing trials for hair loss treatment, showing similar effectiveness between 0.5% and 1.0% dosages, with mild side effects compared to finasteride. Users discuss combining KX-826 with other treatments like minoxidil and clascoterone for better results.

      community Procyanidin B2 Supplement

      in Research/Science  15 upvotes 4 years ago
      User seeks Procyanidin B2 supplement source and asks for dosage comparison. Another user requests study details and apple type importance.

      community Pyrilutamide Update Number Two

      in Update  40 upvotes 3 years ago
      How Pyrilutamide, a hair loss treatment, has improved texture and regrowth of hair without any side effects for users, who are encouraged to post progress photos.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community They've stopped selling this in the UK

      in Ketoconazole  6 upvotes 1 year ago
      Ketoconazole is no longer sold in the UK, and pharmacies have replaced it with non-ketoconazole options. Users are discussing its availability and possible alternatives.

      community ghk-cu is potent 5-ar inhibitor?

      in Product  11 upvotes 2 years ago
      GHK-Cu is a potent inhibitor of the type 1 5-alpha reductase enzyme in hair follicles, which may reduce hair loss without the side effects associated with type 2 5-alpha reductase inhibitors. The user previously experienced side effects with 5-alpha reductase inhibitors and is considering GHK-Cu as an alternative.

      community Pyrilutamide cease and desist from Kintor

      in Transplants  12 upvotes 3 years ago
      Considering a hair transplant, using Pyrilutamide, the potential availability of CosmeRNA, and the significance of taking Minoxidil and Finasteride for long-term results.

      community 2nd day on pyrilutamide - what I noticed so far

      in Treatment  7 upvotes 3 years ago
      The user started using a hair loss treatment called pyrilutamide and experienced mild chest discomfort and tightness, similar to previous side effects from RU58841. They plan to reduce the dosage due to these side effects and will provide an update on the results in 1-2 months.

      community Clascoterone ph3 results ready

      in Research/Science  10 upvotes 4 months ago
      Clascoterone 5% solution showed a 539% improvement in hair count compared to placebo, but the actual increase in hair growth is minimal. Users express skepticism about the effectiveness of hair loss treatments.

      community Pyrilutamide update number 1 - 1 week use

      in Update  55 upvotes 3 years ago
      A user who is using Pyrilutamide, Finasteride, and a homemade topical solution to treat their hair loss. Replies mentioned the potential of Pyrilutamide being a "cure" for hair loss and a reminder that results may not be credited solely to it.

      community Anyone knows if koshine kx-826 has propylene glicol?

      in Product 6 months ago
      Koshine KX-826 has different versions, and the green version uses a plant-based carrier that may be less irritating for those sensitive to propylene glycol. Users report irritation with some versions of KX-826.

      community Combining spironolactone with koshine?

      in Chat 1 year ago
      Combining spironolactone with koshine might enhance the effect of blocking androgen receptors for hair loss treatment. The user suggests adding crushed spironolactone pills to koshine.

      community Is it possible/legal to buy clascoterone in Spain?

      in Treatment  2 upvotes 8 months ago
      The user has tried various hair loss treatments, including topilutamide, alfatradiol, pyrilutamide, and topical spironolactone, but experienced headaches. They are inquiring about the availability and legality of clascoterone in Spain.

      community cosmeRNA finally now it's pyrilutamide turn

      in Chat  48 upvotes 2 years ago
      Hair loss treatments discussed include cosmeRNA, minoxidil, finasteride, RU58841, and pyrilutamide. Users debate effectiveness, side effects, and upcoming treatments, with some expressing skepticism and others optimism.

      community Im struggling with sebderm need help

      in Product  3 upvotes 1 month ago
      The user is struggling with seborrheic dermatitis and plans to try ciclopirox olamine after finding ketoconazole too drying. They are also using finasteride daily.

      community My good/bad experience with Creatine

      in Treatment  30 upvotes 11 months ago
      Creatine may cause increased hair shedding in some individuals, especially those with androgenetic alopecia (AGA), despite its physical performance benefits. Many users report stopping creatine to reduce hair loss, while others believe the effects are anecdotal or due to other factors like increased physical activity.