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      community A less common type of hairloss case

      in Research/Science  5 upvotes 1 month ago
      High-dose Lysine and Histidine supplements caused curly/kinky hair and shedding due to Elastin dysfunction. Minoxidil, white tea, and dark grape juice were mentioned as treatments to inhibit Elastase and mimic Lysyl Oxidase.

      community Pyrilutamide release in Europe?

      in Treatment  2 upvotes 2 years ago
      User asks about Pyrilutamide release in Europe, specifically Germany, and considers importing it from China. No specific treatments mentioned.

      community Trestolone (MENT) as a nuclear treatment

      in Treatment  99 upvotes 3 years ago
      Experimenting with trestolone as a treatment for hair loss in an attempt to avoid DHT-related treatments such as finasteride and dutasteride, and discussing the potential effects of its receptor selectivity on the androgen receptors in the scalp.

      community Received Kintor’s KX-826 Today

      in Product  84 upvotes 1 year ago
      A user received Kintor’s KX-826/Pyrilutamide and shared initial impressions, noting concerns about the product's labeling and marketing. Other users discussed the legitimacy of the product, its effectiveness, and compared it to other treatments like Minoxidil and Finasteride.

      community Verteporfin and Microneedling

      in Treatments 1 year ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community Is Pyri worth it at the moment?

      in Chat  26 upvotes 2 years ago
      The conversation is about the effectiveness and safety of a hair loss treatment called Pyri, with users discussing its availability and comparing it to other treatments like RU58841, fluridil, and alfatradiol. Some users are waiting for FDA approval before using Pyri, while others share their positive experiences with RU58841 and suggest additional treatments with minimal side effects.

      community Dry and itchy scalp after ru58841 and keto. Advice needed

      in Product  3 upvotes 4 years ago
      The user experienced severe scalp itching after using RU58841 and ketoconazole shampoo, despite trying moisturizing treatments. They suspect the issue is related to the propylene glycol in the vehicle and are seeking alternatives.

      community AGA responded to steroid shots? Biopsy wrong? Please help!

      in Female  2 upvotes 1 year ago
      A woman with AGA is using spironolactone, dutasteride, finasteride, oral minoxidil, bicalutamide, and anti-androgenic birth control but still experiences worsening hair loss. Steroid shots temporarily stop her hair shedding, leading her to question her biopsy results.

      community Does anybody else got their hair ruined when on tretinoin?

      in Chat  4 upvotes 1 year ago
      The user experienced hair shedding and follicle shrinkage when using retinoic acid, despite trying different concentrations and frequencies. The hair loss persisted for six months but regrew after stopping the treatment.

      community Lyphar Biotech. China source for RU58841

      in Research/Science  1 upvotes 2 months ago
      The conversation discusses the safety and trustworthiness of ordering RU58841 from Lyphar Biotech in China, with a focus on pricing and reliability. The user is seeking advice on whether to proceed with the purchase or consider alternative sources.

      community Should i stop the treatment seems like nothing works for me.

      in Progress Pictures  23 upvotes 2 years ago
      The conversation is about someone considering stopping their hair loss treatment, which includes minoxidil, finasteride, ketoconazole, microneedling, and oral minoxidil, due to lack of visible results. Replies suggest continuing treatment, considering a hair transplant, and trying dutasteride.

      community My experience with Pyrilutamide

      in Update  43 upvotes 3 years ago
      Two different experiences of using Pyrilutamide, a hair loss treatment, which caused headaches that took around a week to subside in both cases. Other users offered insight into their own experiences with the treatment or suggested alternate treatments such as RU58841 and Minoxidil.

      community Kintor Pharmaceutical Announces AR-PROTAC (GT20029) Approved for Acne and Androgenic Alopecia Clinical Trials in China

      in Technology  13 upvotes 5 years ago
      The conversation discusses the approval of Kintor Pharmaceutical's AR-PROTAC (GT20029) for clinical trials in China for acne and androgenic alopecia. One user expresses optimism about new treatments being developed and seeks clarification on how the new drug works, specifically if it temporarily degrades the AR protein to reduce DHT sensitivity in hair follicles.

      community What’s the deal with pyrilutamide?

      in Research/Science  52 upvotes 3 years ago
      The effectiveness of pyrilutamide, a hair loss treatment, with research results being postponed until September. Various people shared their experiences with topical finasteride, minoxidil and RU58841, as well as other treatments such as dandruff shampoo, group buys and grey markets.

      community Extremely potent catalyst for Minoxidil

      in Minoxidil  4 upvotes 6 years ago
      Using Megatek with minoxidil significantly increases hair growth, especially vellus hairs, but is less effective alone. Biotin and ketoconazole shampoo are also used to support hair health.

      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  734 upvotes 3 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Doctors won't let me try bicalutamide or fin

      in Female  8 upvotes 5 years ago
      Hair loss treatments discussed include 200mg Spiro, bicalutamide, and finasteride. Endocrinologist advises against bicalutamide and finasteride due to potency and risks.

      community Pyrludimide (KX-826) or Breezula (clascoterone)

      in Treatment  9 upvotes 1 month ago
      The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

      community What’s your nuclear protocol???

      in Chat  21 upvotes 2 years ago
      People discussed their intense hair loss treatments, including the use of dutasteride, RU58841, minoxidil, tretinoin, essential oils, microneedling, and various topical sprays. Some users reported success with these methods in preventing hair loss and stimulating hair growth.