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      community I spoke to the Guy who did the Ru58841 (PSK-3841) research

      in Research/Science  289 upvotes 4 years ago
      The conversation discusses RU58841, a compound for hair loss treatment, which was found to be effective in a 6-month trial but was not pursued due to financial issues or marketability concerns, not safety. Some users are considering crowdfunding to release the research data, while others discuss personal experiences and safety concerns with RU58841.

      community Kintor’s GT20029 Phase 1 success

      in Update  73 upvotes 3 years ago
      Kintor's GT20029, a treatment for hair loss, has completed Phase 1 successfully, showing promise as an androgen receptor degrader that could potentially regrow hair. It is considered more effective than Pyrilutamide, with infrequent dosing and minimal systemic absorption.

      community Switch from RU58841 to Pyrilutamide, after 2 years?

      in Treatment  6 upvotes 3 years ago
      A user switched from RU58841 to Pyrilutamide for hair loss treatment after experiencing side effects and continued hair shedding with RU. They are now losing hair faster with Pyrilutamide and questioning if they should revert to RU58841.

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  13 upvotes 1 year ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community High Dose Niacin Update

      in Update  7 upvotes 8 years ago
      High dose niacin (1000mg daily) seems to have halted hair loss but did not regrow lost hair. The user plans to continue due to additional benefits like lower stress and higher good cholesterol.

      community CB-03-01: I need help

      in Treatment  7 upvotes 5 years ago
      The user stopped using finasteride and RU58841 and is considering CB-03-01 for androgenic alopecia but is concerned about the cost and effectiveness, especially at a lower dose than in clinical trials. They are also using minoxidil, micro-needling, and nizoral shampoo but are unsure about the correct application method for CB-03-01.

      community Nanoxidil: a good substitute or a scam?

      in Treatment 1 year ago
      Nanoxidil is considered by some as a substitute for Minoxidil, but users report it as ineffective and expensive. Finasteride is recommended as a more effective treatment, often used with Minoxidil, microneedling, and ketoconazole.

      community Koshine comes under two names apparently

      in Product  1 upvotes 1 year ago
      The conversation is about receiving a shipment of Koshine, also known as Kintor, which is an anti-androgen treatment for hair loss. The user is eager to try the KX-826 product and observe its effects and any side effects.

      community Ultimate Non-5AR (fin/dut) stack?

      in Treatment  1 upvotes 11 months ago
      The conversation discusses alternatives to 5AR inhibitors for hair loss treatment, suggesting options like minoxidil, KX-826, pyrilutimide, microneedling, and topical bicalutamide. Concerns about side effects and the effectiveness of these treatments are also highlighted.

      community Alfatradiol 0.1% anyone know a source?

      in Treatment  3 upvotes 1 year ago
      The conversation is about finding a source for Alfatradiol 0.1% as most available products are 0.025%. A suggestion was made to use four times the dosage of the 0.025% product.

      community HMI-115 when will it be available

      in Research/Science  17 upvotes 3 years ago
      The potential availability of a new hair loss treatment called HMI-115, which has shown promising results in experiments on monkeys but is not yet available to the public. Replies cautioned against using unproven substances from shady labs.

      community It's probably RU58841, which is weak in adenosine.

      in Treatment  14 upvotes 1 year ago
      The conversation is about using adenosine, finasteride, and minoxidil for hair loss treatment. The user ordered a 0.75% adenosine solution and is currently using finasteride 1mg and minoxidil 5%.

      community Anyone tried CB-03-01?does it work ?

      in Research/Science  2 upvotes 8 months ago
      CB-03-01, also known as Breezula, is being considered as an alternative to DHT blockers for hair loss. Users are discussing its effectiveness, potential regrowth, side effects like scalp irritation, and hormonal impacts.

      community biolabshop RU58841 source legit??

      in Product  1 upvotes 1 year ago
      The conversation is about using Biolabshop's RU58841 product, which includes GHK-Cu and melatonin, to improve hair quality and combat hair loss. The user has previously used finasteride, minoxidil, and Anageninc’s RU58841 with success and seeks feedback on the new product, especially from those on anabolic steroids or hormone treatments.

      community RU58841 in powder form from Aliexpress. Is this safe to purchase?

      in Product  3 upvotes 1 year ago
      A user is considering buying RU58841 powder from Aliexpress to mix with Minoxidil for hair loss treatment. Another user warns about the safety concerns of RU58841, especially from unreliable sources, and suggests trying finasteride, oral Minoxidil, and dutasteride first.

      community How can you make your own PP405

      in Research/Science  2 upvotes 8 months ago
      People are discussing making their own PP405 for hair loss treatment using JLX069 and DMSO. There is skepticism about the safety and effectiveness of this homemade solution, with some users expressing concerns about potential risks.

      community Need help with RU58841 (preparation + dosage).

      in Treatment  3 upvotes 9 months ago
      The conversation is about using RU58841 for hair loss treatment, specifically mixing it with minoxidil without propylene glycol due to an allergy. The user is considering starting with a lower concentration of RU58841 and making smaller batches to maintain efficacy.

      community Will pp405 have to be inserted rectally for full benefits?

      in Transgender  32 upvotes 4 months ago
      Pp405 is discussed as a potential hair loss treatment, with humorous suggestions about rectal administration for increased effectiveness. Users joke about unconventional methods and express willingness to try anything for hair regrowth.

      community 10 months progression (plz respond)

      in Is this regrowth?  4 upvotes 6 days ago
      The user is experiencing hair shedding after using minoxidil and is considering switching to dutasteride while planning to increase their oral minoxidil dose. They also use nicotine pouches, Vyvanse, and GHK-Cu, and have noticed thicker eyebrows and lashes from oral minoxidil.

      community PP405 Update and My Take on Pelage

      in Research/Science  86 upvotes 5 months ago
      Pelage Pharmaceuticals raised $120M for their hair loss treatment, PP405, showing strong investor confidence despite limited data. There is skepticism about its efficacy and long-term effects compared to treatments like GT20029.