Search

everythinglearnresearchcommunity

for

Search:↓

People are discussing JXL-069 (PP405) for hair loss, with some experimenting with a 0.05% topical gel. Concerns about safety and efficacy persist due to limited testing and lack of official approval.

The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

The post and conversation are about a user named "Road2Recovery2023" who just got a prescription for 2.5 mg Dutasteride, a treatment for hair loss.

Finasteride is not a miracle drug; results vary widely, with only 2/5 getting good results. Combining treatments like minoxidil and finasteride may help, but expectations should remain low.

A 28-year-old male shared progress pictures showing temple hair growth after using 5mg Minoxidil and 0.5mg Dutasteride since January 1st. Users discussed the effectiveness of these treatments, with some noting increased facial hair growth and others inquiring about the method of application.

A user received a prescription for Dutasteride 0.5 in Europe and asked about the brand. Replies confirmed the brand's quality and suggested using the cheapest gelatin capsule form.

The user experienced increased hair shedding after one month on 0.25 mg finasteride, despite initial improvement. This shedding may be a normal phase in the hair cycle and could improve in the coming months.

The user is experiencing hair loss and has tried various treatments including topical and oral finasteride, minoxidil, dutasteride, and ketoconazole, but continues to lose hair. They are considering alternative solutions like hair systems due to the lack of improvement and a scalp condition called CVG.

The conversation discusses hair regrowth using 2-deoxy-d-ribose (2DDR) combined with minoxidil, with some users noting new hair growth. The original poster has been using minoxidil for 12 years and is considering combining 2DDR with finasteride, despite past side effects.

The user is treating male pattern baldness with oral minoxidil, ketoconazole, derma rolling, rosemary oil, and topical minoxidil, and is considering adding finasteride. They are debating between three finasteride dosing strategies: 1mg daily, 1.25mg every other day, or 1.25mg five days a week, focusing on efficacy, safety, and cost.

The user has been using oral Dutasteride (.5mg) for 104 days and oral Minoxidil (.5mg) for about 2 months to address hair loss. Changes in hair appearance are noted, influenced by haircuts and dyeing, which affect the visibility of thinning areas.

The conversation is about comparing the effectiveness of 5% RU58841 and 0.5% pyrilutamide for hair loss treatment. The user is asking if the higher concentration of RU58841 makes it stronger than the lower dose of pyrilutamide.

A 22-year-old male experiencing diffuse hair thinning has been using finasteride, initially at 0.5mg and then 1mg daily, but sees no improvement. Despite correcting a vitamin D deficiency and noticing some new hair growth, he questions the effectiveness of finasteride.

An 18-year-old is using a high-dose treatment for hair loss, including 2.5 mg dutasteride, topical minoxidil, and injectable GHK-Cu, despite minimal hair loss. Many users suggest reducing the dutasteride dose due to potential side effects and recommend starting with finasteride instead.

The user is concerned about using dutasteride for potential hair loss, fearing it might accelerate balding if not effective. They are unsure about the doctor's diagnosis and are considering starting with finasteride instead.

Finasteride can affect hormone levels, potentially causing symptoms like puffy nipples and testicular pain, and may result in elevated prolactin and high testosterone. The user is seeking interpretation of these changes after taking finasteride.

OP reports that after 3 months on 2.5mg dutasteride, their hair has stopped falling out and is thick again, but they are considering stopping due to potential mood and energy side effects. Other users discuss experiences with finasteride, dutasteride, and side effects, with some suggesting lower doses or alternative treatments like topical applications.

The user is using 0.1% dutasteride, 1% minoxidil with 2% procapil and 0.005% caffeine in the morning, and 1% minoxidil with 2% procapil and 0.01% tretinoin at night. They are concerned about the solution vehicle's effectiveness in preventing systemic absorption and ensuring the products stay around the hair follicles.

User discusses hair loss plateau from December to March, using 0.5 Dutasteride. Others suggest waiting longer for results, keeping sides trimmed, and continuing treatment.

RU58841 is discussed as a hair loss treatment, with users considering lower doses like 2.5% to reduce costs. Some users suggest that if already blocking DHT, lower doses might still be effective unless there's high sensitivity to DHT.

The conversation is about hair loss treatment using finasteride and minoxidil, with the original poster considering adjusting their dosage after experiencing side effects. Other users suggest trying different dosages or adding dutasteride, emphasizing consistency and consulting a specialist if side effects occur.

Dutasteride effectively reduces DHT levels and significantly increases testosterone levels. Users are cautious about adding oral minoxidil due to potential heart issues and are considering dosage adjustments with medical guidance.

The conversation discusses the potential of new hair loss treatments, with a focus on pyrilutamide, gt20029, and topical alfatradiol, and the possibility of improving their effectiveness through methods like increased concentration and microneedling. Dutasteride is also mentioned as a stronger option.

A 22-year-old male uses dutasteride, a serum with 10% minoxidil and 0.5% finasteride, and microneedling for diffuse androgenetic alopecia. Progress pictures show changes from July 2025 to February 2026.

A 20-year-old is using minoxidil and dutasteride for hair regrowth and is questioning if recent changes are due to regrowth or lighting. Users suggest the changes are due to minoxidil and advise not to worry about hair shedding from dutasteride.

PP405 updates are seen as vague and lacking substance, causing frustration among users. Some users report positive effects from using minoxidil and dutasteride, while others remain skeptical about new treatments.

A user is making their own dutasteride solution using MCT oil but is concerned about its effectiveness and bioavailability. They are considering using propylene glycol or adding ethanol for better results, while others suggest the current dosage might be excessive.

Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.

The user is using Dutasteride (90.5mg) and Minoxidil (2.5mg) for hair loss since October 2025 and is seeking feedback on their progress. They provided comparison photos from October 2025 and January 2026.

PP405 shows initial promise for treating androgenetic alopecia, with safety confirmed in early trials, but skepticism remains due to limited data. Further trials are needed to determine its true efficacy and potential market impact.