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GlossaryDecorin

small proteoglycan that regulates collagen fiber formation

Decorin is a small proteoglycan found in the extracellular matrix of connective tissues. It plays a crucial role in regulating collagen fibrillogenesis, which is the process of collagen fiber formation, and helps maintain the structural integrity of tissues. Additionally, decorin has been shown to influence cell growth and wound healing, making it significant in both normal physiological processes and pathological conditions.

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community Is this basically the closest thing to a cure? I don’t know why more men don’t use wigs. Thought?

in Hair Systems 1093 upvotes 11 months ago

Wigs are considered a temporary solution for hair loss, with concerns about cost, maintenance, and social stigma. Many prefer treatments like finasteride, minoxidil, or hair transplants for more permanent results.

community Carrier for homemade topical Finasteride

in Chat 5 upvotes 1 year ago

The conversation is about making topical finasteride using stemoxydine as a carrier. The user is considering buying Redken Cerafill Hair Re-Densifying Treatment (Stemoxydine) 90ml for this purpose.

community Hi, I got some regrowth recently and I attribute it to DICLOFENAC

in Research/Science 6 upvotes 2 years ago

The user started balding at 16/17 and tried various treatments including minoxidil, finasteride, and dutasteride with little success. They recently started applying diclofenac gel to their bald areas and noticed some hair regrowth, attributing this to diclofenac's ability to lower prolactin levels and its anti-inflammatory effects.

community Derminator2 causing scars (microscope images attached)

in Microneedling 61 upvotes 1 year ago

User experienced scarring from microneedling at fast speed and paused treatment for 3-4 weeks to recover. Advice given includes waiting a full month for recovery to avoid scars.

community clascoterone powder to topical diy

in Product 3 upvotes 2 weeks ago

The conversation is about making a topical solution from clascoterone powder, with references to using a RU58841 mixing guide for guidance. Concerns about product authenticity and bulk purchase requirements are also discussed.

community Clascoterone is the way to go if you cannot use DHT blockers

in Chat 7 upvotes 2 weeks ago

Clascoterone is suggested as an alternative for those who experience side effects from finasteride and dutasteride. It is not widely available yet, but some users are obtaining it from compounding pharmacies or suppliers like Echemi.

community Has anyone had any success with Carpronium chloride 5%?

in Product 3 upvotes 5 years ago

Carpronium chloride 5% is a hair growth treatment in Japan, considered less effective than minoxidil or finasteride. Some users report moderate success with it, but its efficacy is not well-verified.

community RESULTS: 1% Clascoterone Cream. (3 months Jan-Mar 2026)

in Progress Pictures 14 upvotes 1 month ago

The user reported slight improvement in hairline using 1% Clascoterone cream over three months but found it too costly to continue. They expressed interest in trying a 5% concentration if it becomes available at a reasonable price.

community Anyone has experienced Collagen Synthesis with min ? (wrinkles, dark circles...)

in Question 11 upvotes 7 years ago

Minoxidil may cause wrinkles and dark circles, which some users report can be mitigated by adjusting dosage. Reactions vary, and while some dismiss these side effects, others experience significant changes.

community Adding the final piece to my fin/min/derma stamp routine

in Ketoconazole 6 upvotes 1 year ago

The user has been using finasteride, minoxidil, and a derma stamp for 3 months with significant improvement. They are now adding ketoconazole to their routine.

community Clinical Trial: Clascoterone (Cortexolone 17A-Propionate)

in Research/Science 24 upvotes 2 years ago

A user is joining a clinical trial for Clascoterone, a drug approved for acne but being tested for hair loss. They previously tried finasteride with limited success and plan to share updates on their experience with the new treatment.

community And just like that, everyone stopped talking about Clascoterone?

in Research/Science 26 upvotes 3 months ago

Clascoterone showed promising initial results for hair regrowth but failed to replicate them, leading to disappointment. Users discuss combining it with minoxidil and other treatments, noting its current availability only in lower concentrations.

community My dermatologist gave me Ell cranell?

in Treatment 4 upvotes 2 years ago

The user is seeking advice on a hair loss treatment called Ell Cranell, which contains Alfatradiol. Another user shared information from a study stating that Alfatradiol only slows down or stabilizes hair loss, but does not increase hair density or thickness.

community Minxodil collegen synthesis decrease?

in Minoxidil 3 upvotes 1 year ago

Minoxidil may age skin by slowing collagen synthesis, but using collagen peptides and a basic skincare routine might counteract this. Foam minoxidil could reduce systemic absorption and avoid alcohol-related side effects.

community two months on 2-deoxy-d-ribose (2ddr)

in Progress Pictures 10 upvotes 10 months ago

The conversation discusses hair regrowth using 2-deoxy-d-ribose (2DDR) combined with minoxidil, with some users noting new hair growth. The original poster has been using minoxidil for 12 years and is considering combining 2DDR with finasteride, despite past side effects.

community Information regarding Follicusan DP?

in Product 3 upvotes 2 years ago

Follicusan DP is discussed as a potential alternative to Minoxidil without side effects, but information is scarce. It is noted to be of German origin and details on its mechanism are limited.

community Question about clascoterone acne cream

in Treatment 2 upvotes 1 month ago

Clascoterone cream can be used on the scalp, but it may not be effective due to its dosage. AR antagonists like clascoterone are generally less effective than 5AR inhibitors for hair loss.

community Topical min and dermarolling with seborrheic dermatitis

in Minoxidil 4 upvotes 1 month ago

The user is managing hair loss with oral finasteride, recently switching to dutasteride, and topical minoxidil, but faces challenges due to seborrheic dermatitis. They seek advice on effective regrowth methods that don't worsen their condition, with suggestions including various shampoos like Vichy Dercos and ketoconazole.

community Derma roll, tretinoin, minoxidil

in Research/Science 3 upvotes 1 year ago

Use tretinoin three times a week, dermaroll once a week, and apply minoxidil daily, but avoid using all three on the same day. Tretinoin is preferred over hydrocortisone and should not be used immediately after dermarolling.

community Anyone using Finastopic (no pg Isdin)?

in Product 2 upvotes 2 years ago

The conversation discusses the use of Finastopic, a carrier for finasteride solutions by Isdin, and compares it to a standard propylene glycol (PG) solution. The user was prescribed a 1% finasteride solution using Finastopic and has been using a self-compounded 0.025% topical finasteride with minoxidil.

community 3 years of irregular derma rolling and min/Redensyl

in Progress Pictures 4 upvotes 2 years ago

The conversation is about someone's three-year experience with irregular derma rolling, Minoxidil, and Redensyl for hair loss, hoping to thicken areas with fine hair.

community Breezula - who tried CB0301/Clascoterone from gray marked/pharmas ?

in Research/Science 1 upvotes 3 months ago

The conversation discusses using CB0301/Clascoterone as a potential treatment for hair loss, especially for those experiencing side effects from finasteride and dutasteride. The user currently uses oral minoxidil and considers combining it with other treatments like kx826, DHT blocker supplements, and 2% Nizoral shampoo.

community the ordinary retinol & minoxidil

in Minoxidil 13 upvotes 1 year ago

Using retinol with minoxidil may not be as effective as tretinoin, but retinaldehyde or adapalene could be alternatives. A micro-roller with minoxidil is suggested for better results.

community Just got my Dualgen-5R, the one with retinoic acid (tretinoin) but without the fin.

in Minoxidil 6 upvotes 5 years ago

The user has been using Minoxidil and finasteride with success and is now trying Dualgen-5R with retinoic acid but without finasteride, along with microneedling. They plan to share results in 5-6 months.

community For everyone buying 2-deoxy-d-ribose (2ddr)

in Research/Science 12 upvotes 1 year ago

The conversation discusses using 2-deoxy-d-ribose (2DDR) for hair regrowth, with users sharing mixed experiences and side effects like hair loss in new areas and increased anxiety. The original poster plans to continue testing and comparing it to minoxidil, noting potential instability in 2DDR formulations.

community what do you think about Ell-Cranell + Quercetin

in Treatment 6 upvotes 2 years ago

The post discusses the use of El-Cranell, which contains Alfatradiol, and Quercetin as a treatment for hair loss. The user is seeking recommendations on the amount of Quercetin to add to the solution. The conclusion of the document is that Quercetin has been shown to stimulate hair growth and inhibit DHT, and combining it with zinc/copper may have a synergistic effect.

community making a clascoterone lotion from powder

in Technology 2 upvotes 1 year ago

A user is considering making a 2% clascoterone lotion from powder due to unavailability in their location. They plan to mix clascoterone powder with retinol lotion and use literature to determine the correct dosage.

community Taking part in a Clascoterone Study

in Treatment 6 upvotes 2 years ago

The conversation is about a person considering participating in a study for Clascoterone, a topical cream for hair loss, and seeking advice on potential side effects. They have mild hair loss and are not currently using other treatments like finasteride.

community Clascoterone 5% Delivers Strong Phase 3 Hair-Growth Results | Dermatology Times

in Research/Science 41 upvotes 5 months ago

Clascoterone 5% shows promising hair growth results but is criticized for high cost and unclear effectiveness compared to other treatments like finasteride. Glenmark is testing a combination of Clascoterone 7.5% and Minoxidil 5% in India.

community Clascoterone 5% solution infographic

in Update 132 upvotes 5 months ago

Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.