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PP405 shows promise for hair regrowth by manipulating stem cell characteristics and lactate dehydrogenase, with Phase 2a trials pending. Google Ventures' $15M investment suggests confidence, but results and market availability remain uncertain.

User shares 4-month progress using daily minoxidil, topical finasteride, and microneedling. Results spark debate on effectiveness and authenticity.

Betacarotene's effect on hair loss is discussed, with concerns about excessive vitamin A. The user also questions if 15mg melatonin impacts vitamin A levels.

The conversation is about a user's hair transplant progress using 3000 grafts with DHI technique, foam Minoxidil, Tretinoin, and Dutasteride after 5.5 months. Commenters are impressed with the results, noting significant improvement.

The conversation is about OP's hair regrowth progress using dutasteride, 5% minoxidil, dermarolling, ketoconazole, adapalene, and vitamin D. Some users doubt the progress, attributing it to longer hair and lighting, while others congratulate OP on the visible improvement.

A 59-year-old man with significant hair loss has seen some improvement, including reversal of Retrograde Alopecia and darkening of hair, after switching to RU58841 and a new minoxidil base solution with additional ingredients. He also changed from a derma roller to a derma stamp for application.

The conversation discusses concerns about microneedling potentially causing damage before a hair transplant, with users sharing their experiences and techniques. Specific treatments mentioned include using a dermapen at various depths and speeds, with some users advising against self-treatment.

The post and conversation are about a user's progress with microneedling and minoxidil for hair loss. The user is happy with the progress and plans to continue with the treatment, without using finasteride.

The user has been using a daily topical spray of finasteride and minoxidil, along with occasional microneedling, to address hair loss since August 2023, and is considering switching to oral medication for convenience and cost reasons. Despite progress, they are exploring options like increasing microneedling frequency or potentially undergoing a hair transplant to address a stubborn spot.

User shared 4.5-month hair loss treatment results using Fin, Minoxidil, and microneedling. Others discussed postponing hair transplant and adjusting microneedling depth.

Hair and skin products need 4-6 weeks to show results, and consistency is crucial for effectiveness. Track progress weekly with photos and notes, and if no changes occur after 8 weeks, consider changing products.

Microneedling is discussed as a method to improve hair growth, with users sharing their experiences and results using different needle depths and frequencies. Treatments mentioned include minoxidil, finasteride, rosemary oil, and saw palmetto supplements.

A user is trying 2-deoxy-D-ribose with distilled water for hair growth, observing new hair and skin pigmentation changes. Others compare it to Minoxidil, expressing interest and caution about its effectiveness and safety.

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

The conversation is about finding the optimal concentration of topical melatonin for hair loss treatment. The user is considering making their own solution and is unsure whether a higher concentration is more effective for deactivating prolactin receptors.

A 43-year-old male from Sydney is seeking advice on using a Dermapen with Minoxidil for hair loss treatment. He inquires about the frequency of Dermapen use, needle depth, cartridge type, timing for applying Minoxidil, safety of numbing cream, and cartridge reuse.

Pelage plans to conduct two Phase 3 trials for PP405, a new hair loss treatment, which may take about a year to complete. Users discuss various hair loss treatments, including pyrilutamide, minoxidil, finasteride, and clascoterone, with some expressing impatience over the lengthy trial process compared to faster drug approvals like the COVID vaccine.

The user is struggling with seborrheic dermatitis and plans to try ciclopirox olamine after finding ketoconazole too drying. They are also using finasteride daily.

The conversation discusses a hair loss treatment formulation containing cyclosporin, minoxidil, and tacrolimus, and mentions ongoing research on hair color reversal. The treatment showed high efficacy in restoring hair color in trials with 40 to 50 people.

A 35-year-old male experienced significant hair improvement using microneedling, finasteride, minoxidil, and keto shampoo. He adjusted his microneedling routine for better results.

The user shared progress pictures after 3 months of using topical finasteride, minoxidil, and microneedling for hair loss. They plan a hair transplant at 6 months, and others inquired about microneedling frequency and depth.

A 29-year-old man experienced significant hair thickening at the front and top after using finasteride and microneedling for two months, as noticed by his hairdresser. He used 0.5 mg/day of finasteride orally, switched to a topical solution, and performed microneedling with a Derminator2 every 6-7 days.

A user shared their 7-month progress on hair regrowth using a regimen of dutasteride, minoxidil, stemoxydine, microneedling, and keto shampoo. They noted significant improvement, particularly in vellus hair growth, and discussed the potential addition of RU58841, though they experienced side effects with it previously.

Excessive use of topical minoxidil led to unwanted facial changes and side effects. The user plans to switch to oral minoxidil with microneedling for hair regrowth.

The user reported significant hair regrowth after seven months using topical minoxidil 5% combined with 0.1% finasteride and weekly micro needling. The community responded positively, noting visible improvement and discussing the effectiveness of topical versus oral finasteride.

Microneedling is unlikely to damage existing hair if done with a device using a smaller needle count, like a 9-needle cartridge, and a stamping motion. Hair follicles are deeper than the typical needle penetration depth.

The conversation discusses experimenting with microneedling for hair loss, with OP considering using a 3mm derma-stamp. Other users advise against going beyond 1.5mm to avoid damage.

The user shared progress after 9 months of using finasteride, minoxidil, and dermarolling for hair loss, despite some inconsistency in treatment. They are pleased with the results and plan to stop updating.

This conversation is about a user's progress pictures after using minoxidil twice a day and microneedling for 1.5 months, with other users recommending finasteride as an additional treatment. They are also discussing the frequency and depth of the microneedling.

The conversation discusses the effectiveness of topical tretinoin as a monotherapy for hair loss, with users suggesting it may not be as effective as minoxidil or finasteride. The original poster is considering other options like a phenol peel and is concerned about the risks of derma rolling.