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      community Switching to a more aggressive stack

      in Progress Pictures  4 upvotes 3 months ago
      The conversation is about a user switching to a more aggressive hair loss treatment, adding dutasteride 0.5mg and oral minoxidil 2.5mg to their current regimen of finasteride 0.02%, minoxidil 5%, biotin, massages, and microneedling. Users suggest increasing finasteride dosage and caution about potential side effects of oral minoxidil.

      community Ru58841 ruined my life. Here’s why.

      in Product  130 upvotes 4 years ago
      User experienced shortness of breath, high blood pressure, red eyes, and eye floaters after using RU58841 for hair loss. They warn others to avoid RU58841 and stick to finasteride, minoxidil, and dutasteride.
      M20 with Hair Loss - Clascoterone an Option?

      community M20 with Hair Loss - Clascoterone an Option?

      in Basic Questions  65 upvotes 2 months ago
      A 20-year-old is experiencing hair thinning and is considering Clascoterone and Minoxidil as treatments, avoiding finasteride due to concerns about fertility and hormones. A suggestion was made to use Clascoterone for local DHT targeting and combine it with Minoxidil for maintenance and regrowth while avoiding systemic side effects.

      community 18M 10 months on anti-androgens and oral min

      in Progress Pictures  50 upvotes 2 years ago
      An 18-year-old male used anti-androgens and oral Minoxidil for 10 months to treat hair loss. He initially used 1mg Finasteride and 5% topical Minoxidil for 5 months, then switched to Dutasteride for 4.5 months and inconsistently used 5mg oral Minoxidil for 2 months due to availability issues.

      community What’s your views on clascoterone 5% topical solution by cosmo

      in Research/Science  24 upvotes 6 months ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community Diffuse thinning is the worst. Nothing helps.

      in Update 7 months ago
      The user is experiencing diffuse thinning and has tried treatments like topical and oral finasteride, oral dutasteride, topical minoxidil, microneedling, melatonin, and caffeine without success. Despite using these treatments for over four years, the user reports continued hair thinning and is considering trying RU58841.

      community Fun thought experiment about halting hair loss permamently

      in Research/Science  60 upvotes 2 years ago
      A user proposed genetically engineering scalp stem cells to stop androgen receptors from causing hair loss. Others discussed the feasibility, existing research, and potential issues with this approach, including targeting the correct cells and unintended effects.

      community Clascoterone - what we have right now

      in Research/Science  23 upvotes 4 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Pyrilutamide and RU alternatives?

      in Treatment  1 upvotes 1 year ago
      Pyrilutamide is officially available for purchase, and users suggest Fluridil as an alternative topical anti-androgen. Some users report positive results with pyrilutamide from Koshine.

      community Dutasteride is amazing even for women with FAGA!

      in Female  151 upvotes 9 months ago
      Dutasteride significantly improved hair health and reduced shedding for a woman with PCOS and hyperandrogenism, without causing depression or anxiety, unlike finasteride. Dutasteride also helped with PMDD symptoms and had no side effects, though it changed hair texture.

      community 1 Year Estradiol HRT, Oral Finasteride, Bicalutamide, Cyproterone. (20MTF)

      in Transgender  4 upvotes 2 years ago
      The conversation discusses a 20-year-old transgender female's one-year experience with hair loss treatments, including Estradiol HRT, oral Finasteride, Bicalutamide, and Cyproterone. Specific treatments used for hair loss are oral Finasteride and potentially Estradiol as part of hormone replacement therapy.

      community Shedding tremendously on RU5841

      in Chat  6 upvotes 2 months ago
      The user is experiencing significant hair shedding after starting RU58841, despite using dutasteride and oral minoxidil for over a year without stabilization. Others suggest continuing the treatment as shedding can be a normal phase, but caution that RU58841 is unpredictable.

      community Low Estradiol while on 1mg Fin, what should I do?

      in Finasteride/Dutasteride  2 upvotes 1 year ago
      A user on 1mg finasteride for a year has low estradiol levels but no significant symptoms, and others suggest monitoring without immediate concern. Some users discuss potential effects of low estrogen, like low libido, but the user reports no erectile dysfunction.

      community Libido on Finasteride

       4 upvotes 11 years ago
      The conversation discusses the effects of finasteride on libido, with the original poster experiencing a significant decrease in sexual desire after starting the medication. Other users share similar experiences and suggest potential remedies, including Vitamin E supplementation and lifestyle changes like avoiding pornography.

      community My hormones are going crazy - result

      in Update  5 upvotes 1 year ago
      User reports worsening hair loss despite using Avodart 0.5mg daily and 2ml of Minoxidil daily for over three years. They maintain a healthy lifestyle and are athletic.

      community Curious about 'nuclear' stacks

      in Research/Science  1 upvotes 1 year ago
      The conversation discusses using higher doses of minoxidil and finasteride, considering dutasteride, and exploring other treatments like RU58841 for hair preservation. The user reports no side effects after six months and is interested in advanced treatment combinations.

      community Nizoral ketaconazole any good for dht reduction

      in Ketoconazole  8 upvotes 5 years ago
      A 17-year-old is looking for alternatives to finasteride for DHT control to preserve hair, considering ketoconazole shampoo for its potential to inhibit 5AR and also thinking about using caffeine-containing shampoos like alpecin or watermans.

      community Cheap topical anti-androgens recommendations?

      in Treatment  4 upvotes 6 months ago
      The conversation is about finding affordable topical anti-androgens for hair loss. The user is currently using finasteride, dutasteride, and oral minoxidil, and is advised that additional topical treatments may not be necessary.

      community Will minoxidil not work if there’s too much DHT present in the scalp?

      in Minoxidil  5 upvotes 2 years ago
      The user has been using topical finasteride and minoxidil for five months with little progress and is considering oral dutasteride to lower DHT levels, questioning if minoxidil is more effective with reduced DHT. They also use microneedling and tretinoin in their treatment routine.

      community Pyrilutamide or RU or cb-03-01?

      in Minoxidil  2 upvotes 6 months ago
      The conversation discusses using Minoxidil, finasteride, RU58841, and pyrilutamide for hair loss treatment. The user is considering adding a topical treatment and has not experienced side effects from current treatments.

      community It is what it is with some people

      in Satire  162 upvotes 5 months ago
      Hair loss treatments like finasteride and dutasteride are discussed, with concerns about side effects such as depression and brain fog. Some users argue about the necessity and impact of DHT on libido and other bodily functions.

      community Dutasteride High Libido. How come we don't talk about this?

      in Finasteride/Dutasteride  210 upvotes 1 year ago
      Dutasteride and finasteride can affect libido differently, with some experiencing increased libido and others decreased libido or erectile dysfunction. Dutasteride may increase testosterone levels but can also cause side effects like liver enzyme changes, while topical finasteride may have fewer sexual side effects.