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community Why doesn't phase 3 of PP405 start straight away?

in Chat 14 upvotes 6 months ago

Pelage is delaying the start of phase 3 trials for PP405 to 2026 due to necessary regulatory processes, despite having $120 million in funding. Users discuss the potential of PP405 for hair regrowth, with some expressing skepticism and others hopeful for new treatments like Breezula.

community pyrilutamide phase 2 results right here, thanks to user Glaringbooch

in Chat 43 upvotes 4 years ago

Pyrilutamide, a new drug being tested to combat hair loss that has been found to perform comparably or better than finasteride and dutasteride in the initial 6 months of treatment with minimal reported side effects.

community AMA: Fin for almost 18 months (update/pics/regime included)

in Finasteride 11 upvotes 8 years ago

User discusses using finasteride, ketoconazole, fish oil, nettle root, saw palmetto, emu oil, and plans to start minoxidil for hair loss. They report maintaining hair with minor side effects like slightly lower libido and watery semen.

community any females on RU58841/minoxidil 2.5%?

in Minoxidil 6 upvotes 4 years ago

A female user is considering using RU58841 with minoxidil 2.5% to reduce side effects like facial hair from minoxidil 5%, while also using copper peptides and a hair serum. Other users discuss alternative treatments like spironolactone, alfatradiol, and the side effects of finasteride.

community Phase II for Technoderma Therepeutic's TDM-105795 set to begin in April tentatively

in Research/Science 40 upvotes 3 years ago

Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.

community What are the 'safer' alternatives to RU58841?

in Research/Science 2 upvotes 1 year ago

A user discusses switching from RU58841 to Pyrilutamide due to side effects like fatigue, brain fog, and elevated heart rate. They have used dutasteride, finasteride, and minoxidil, and are seeking safer alternatives.

community Why nobody uses 0.25% (2.5mg/ml)?

in Treatment 66 upvotes 2 years ago

The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

community Retinol substitute for Tretinoin

in Minoxidil 4 upvotes 1 year ago

The user is seeking a substitute for Tretinoin to enhance the effectiveness of Minoxidil for hair loss. They are considering using Retinol as an alternative.

community Sprinkle that PP405 on my scalp like I sprinkle salt on my stake

in Research/Science 119 upvotes 11 months ago

PP405 shows promise for hair growth with significant results after 4 weeks, but skepticism exists due to its unavailability. Some users are hopeful for its potential, while others express concerns about side effects and market release delays.

community Does pyri/kx826 degrade in exposure to bathroom light?

in Treatment 5 upvotes 1 year ago

The conversation discusses concerns about RU58841 degrading when exposed to light and transferring pyri to a dark glass bottle to prevent this. The user keeps the pyri out for only two minutes before storing it in a dark place.

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