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      community Isotretinoin and Tretinoin difference

      in Product  2 upvotes 1 year ago
      Isotretinoin and tretinoin are different; isotretinoin can cause hair loss and has more side effects. Tretinoin may affect minoxidil absorption, and users suggest waiting before applying minoxidil.

      community Comparing the effect of T suppression and DHT suppression

      in Transgender  89 upvotes 1 year ago
      The conversation discusses the use of 5-alpha-reductase inhibitors like finasteride and dutasteride for hair loss in transgender women, particularly in relation to testosterone suppression. The original poster has been using dutasteride and is considering stopping it due to undetectable testosterone levels.

      community making a clascoterone lotion from powder

      in Technology  2 upvotes 1 year ago
      A user is considering making a 2% clascoterone lotion from powder due to unavailability in their location. They plan to mix clascoterone powder with retinol lotion and use literature to determine the correct dosage.

      community Has anyone used Magnesium L-Threonate ?

       70 upvotes 7 years ago
      Magnesium L-Threonate may help treat balding by reducing DKK-1 expression without affecting DHT. Users discuss its potential effectiveness and application methods, with some considering trying it topically.

      community Seeking Advice on Tretinoin Strength for Minoxidil Success at Age 30

      in Basic Questions  190 upvotes 1 month ago
      The user is considering adjusting tretinoin strength to enhance minoxidil effectiveness, questioning whether to use 0.025% or 0.01% instead of 0.05% due to increased hair shedding. They have been using finasteride, minoxidil, and Nizoral, and are contemplating reintroducing microneedling.

      community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

      in Chat  9 upvotes 5 years ago
      The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

      community How to use tretinoin with min?

      in Chat  8 upvotes 1 month ago
      Using tretinoin with minoxidil may improve absorption but results vary; some users see improved follicle growth while others notice no significant difference. Applying tretinoin before minoxidil is suggested by some users.

      community Alfatradiol only for mild thinning

      in Product  1 upvotes 7 months ago
      Alfatradiol is considered safe but less effective than finasteride for hair loss. One user reported subtle regrowth using alfatradiol with finasteride and minoxidil, while another found alfatradiol ineffective.

      community 0.25 % fin and 0.25% dut together topically

      in Treatment  3 upvotes 6 months ago
      The user is dissatisfied with the results of using 0.3% finasteride and 6% minoxidil for hair thinning and is considering a topical treatment combining finasteride, dutasteride, minoxidil, melatonin, caffeine, and latanoprost. Another user suggests that high topical concentrations can lead to systemic exposure and recommends using oral dutasteride and microdosing topical finasteride.

      community Does anyone have experience with topical dut?

      in Finasteride/Dutasteride  7 upvotes 3 years ago
      The user has been using minoxidil for hair loss and is considering trying a compounded topical treatment with 0.1% dutasteride, minoxidil, tretinoin, collagen, and silicon, as recommended by a trichologist. They learned that dutasteride might be more effective than finasteride and are seeking opinions on the use of topical dutasteride.

      community Trichosol, polyethylene glycol, and DMSO

      in Minoxidil  3 upvotes 2 years ago
      The user experiences irritation from alcohols in minoxidil and is considering alternatives like trichosol mixed with polyethylene glycol or DMSO. They seek advice on the best nonirritating option.

      community Once daily topical Min, weekly 1.5 mm dermarolling

      in Progress Pictures  35 upvotes 2 years ago
      The user has been using 5% minoxidil once daily and microneedling with a 1.5 mm dermaroller weekly for three months, considering increasing minoxidil usage but avoiding finasteride due to libido concerns. Another person suggests considering other treatments like RU58841, alfatradiol, topical finasteride, clascoterone, or saw palmetto since not using a DHT blocker could be less effective.

      community Topical tretinoin increases minoxidil absorption by 3x. Thoughts?

      in Minoxidil  36 upvotes 7 years ago
      Topical tretinoin can increase the absorption of minoxidil by three times, which may enhance its effectiveness for hair loss treatment. Tretinoin causes increased skin turnover, making the skin more permeable and potentially improving minoxidil's efficacy.

      community Minoxidil 5% with 0.01% tretinoin

      in Treatment  1 upvotes 1 year ago
      Minoxidil 5% combined with 0.01% tretinoin may be as effective as using minoxidil twice daily. Users discuss switching to oral minoxidil for consistency, with concerns about side effects.

      community Alfatradiol 0.1% anyone know a source?

      in Treatment  3 upvotes 1 year ago
      The conversation is about finding a source for Alfatradiol 0.1% as most available products are 0.025%. A suggestion was made to use four times the dosage of the 0.025% product.

      community Trichotest Results: no Finasteride

      in Finasteride/Dutasteride  5 upvotes 4 years ago
      The user received trichotest results indicating finasteride is ineffective for them, and they plan to use dutasteride mesotherapy and add cetirizine to minoxidil. They seek advice on incorporating dutasteride into their regimen.

      community Topical solutions combining minoxidil and finasteride?

      in Treatment  2 upvotes 10 months ago
      A user is seeking advice on creating a topical solution combining minoxidil, finasteride, and tretinoin for hair loss, and is unsure about optimal concentrations and availability. Another user shares their custom formula with tretinoin 0.015%, finasteride 0.025%, and minoxidil 5%, and mentions taking oral dutasteride 0.25mg daily.

      community Blood Results before and after Topical Finasteride mix with Minoxidil

      in Finasteride  9 upvotes 6 years ago
      A user reported that after using a topical mix of finasteride and minoxidil, their DHT levels decreased, testosterone and estradiol levels lowered unexpectedly, and they are considering vitamin D3 supplements due to deficiency. They apply the mix 3-4 times a week and use minoxidil on other days. Another user commented that finasteride typically increases testosterone, not decreases it.

      community further reduce DHT in the scalp

      in Finasteride/Dutasteride  428 upvotes 3 months ago
      The conversation discusses methods to further reduce DHT in the scalp for hair loss treatment, with users suggesting various approaches like using dutasteride, minoxidil, tretinoin, and natural supplements like pumpkin seed oil. Some users also mention using topical applications and scalp massages to enhance the effectiveness of these treatments.