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The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.

The user has been using topical minoxidil and dutasteride but is experiencing significant hair shedding, including smaller hairs. They are concerned if this shedding indicates the treatment is working.

Topical dutasteride, particularly at 0.05%, shows greater hair density improvement than oral finasteride over 24 weeks, though hair thickness gains are similar. Some users report side effects with topical treatments, but others find them effective for maintaining hair without significant systemic absorption.

The user shared progress on hair regrowth using 5% topical minoxidil, 2% keto shampoo, oral finasteride, and recently switched to daily dutasteride. They reported positive results without significant side effects and are hopeful for further improvement.

Breezula (clascoterone) and Formula 82F (topical finasteride) are treatments for hair loss that block DHT differently; Breezula competes with DHT at the hormone receptor site without systemic effects, while 82F inhibits the enzyme that converts testosterone to DHT. Breezula may work for those who don't respond to finasteride and vice versa.

The conversation discusses a last-resort hair loss treatment combining topical finasteride, minoxidil, melatonin, and progesterone, with claims that topical finasteride can inhibit up to 52% of scalp DHT. One reply clarifies that progesterone is not an anti-androgen but has anti-androgenic properties because it competes with androgens for receptors.

User is experiencing scalp itch and hair loss despite using Nizoral, Minoxidil, derma rolling, and Finasteride for 6 months. They are considering switching to Dutasteride.

A 17-year-old is looking for alternatives to finasteride for DHT control to preserve hair, considering ketoconazole shampoo for its potential to inhibit 5AR and also thinking about using caffeine-containing shampoos like alpecin or watermans.

The conversation is about a topical spray containing finasteride, minoxidil, and tretinoin, with users discussing its effectiveness compared to more established brands. One user mentions using a product with 5% minoxidil, 0.15% finasteride, and 0.15% tretinoin.

The user is happy with the progress in hair density after using a regimen of oral Dutasteride, topical Minoxidil, Tretinoin cream, Ketoconazole shampoo, and an LLLT helmet. They reported no side effects and noted that Dutasteride and Tretinoin were particularly effective.

Breezula's effectiveness is uncertain, with some users skeptical about its potential and others noting its recent availability on the grey market. A user reported success with a stack of Dutasteride (oral), Minoxidil (topical), and RU58841 (topical), achieving significant hair improvement after 18 months.

AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

User considers trying Pyrilutamide for hair loss and itch relief. Another user shares positive experience with Pyrilutamide, no side effects.

The user reported positive results after 2 months using dutasteride 0.5mg, topical minoxidil daily, ketoconazole 3 times a week, and a derma roller once a week, with minimal side effects. They experienced increased hair growth and are optimistic about future results.

A user's 12 month update on treatment for hair loss, which include oral dutasteride and minoxidil, topical RU88541 and minoxidil, microneedling with hyaluronic acid and FinDuta, experiencing no side effects, positive results and inspiring other users.

Dutasteride Mesotherapy for hair loss is discussed, noting its potential to lower scalp DHT without side effects. Concerns include the inconvenience of injections, lack of reputable studies, and availability issues.

Higher doses of dutasteride, such as 2.5mg, are more effective at reducing scalp DHT than 0.5mg, but are costly and inconvenient. A 1mg dose is considered a more affordable and practical option, though its efficacy is uncertain.

The user reports that using topical Dutasteride has stopped their hair loss, and they are curious about potential side effects and regrowth. They also mention having scalp psoriasis and past SSRI use affecting libido.

People are discussing hair loss treatments, including pyrilutamide, minoxidil, dutasteride, alfatradiol, and bimatoprost. Users share their experiences and side effects, noting that pyrilutamide is considered more effective and safer than RU58841.

User experienced slow gains with topical fin+min, switched to topical dut+min, and considered adding Eucapil. Another user suggested DUT may be less effective topically due to high molar mass and mentioned Fluridil as a weak anti-androgen that could help.

OP used minoxidil for 15 months and pyrilutamide for 46 days, achieving desired results without side effects. Users discussed alternatives like dutasteride and finasteride, with concerns about side effects like erectile dysfunction.

The user has been using oral Dutasteride, RU58841, and Minoxidil for three years without success and is considering adding topical Finasteride or Dutasteride to target DHT both locally and systemically. Other users suggest sticking to a consistent treatment plan, exploring different combinations, and considering other factors like potential misdiagnosis or inconsistent medication use.

The user experienced significant hair regrowth using dutasteride (0.5 mg three times a week) and RU58841 (5% once a day), with no side effects reported from RU58841. They are considering increasing the RU58841 dose or adding minoxidil for further improvement.

Dutasteride, at 1 mg daily, was used for hair regrowth, with initial shedding and side effects like watery semen and increased libido. The user previously tried finasteride and minoxidil but switched to dutasteride for stronger, sustained results.

The conversation discusses GT20029, a compound by Kintor Pharma that degrades androgen receptors and is in trials, with potential as a hair loss cure. Another promising treatment mentioned is an antibody that blocks prolactin and has shown positive results in macaques.

The post discusses the effectiveness of pyrilutamide for hair loss. The user maintains hair with alfatrodial, fluridil, minoxidil, and keto shampoo but is seeking a simpler and cheaper alternative.

A user diluted a Hims spray with Kirkland's minoxidil to lower finasteride concentration and has been applying it for nearly 3 months, noticing baby hairs at the temples. They also use a dermastamp, saw palmetto, and biotin supplements, and are seeking advice on their hair loss stage.

Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

The user shared progress pictures showing improved hair growth at the temples after 2.5 months using oral finasteride/dutasteride, ketoconazole shampoo, minoxidil, tretinoin, and dermarolling. The user reported no side effects from the medications and noted inconsistent microneedling.

A user experienced significant hair shedding after 8 months of using oral dutasteride (0.5 mg), minoxidil (2.5 mg), and biotin (5 mg) daily. They are concerned about the effectiveness of the treatment and possible resistance to dutasteride.