Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.
The user observed some regrowth and longer baby hairs after one month of using finasteride, despite experiencing increased shedding. They noted no side effects except for clear semen.
A 24-year-old male has been using oral Minoxidil (2.5mg daily) and daily Dutasteride for hair loss, noticing slight thickening but no major regrowth. Users suggest increasing Minoxidil dosage to 5mg and maintaining consistency, with some recommending additional treatments like topical Minoxidil or considering a hair transplant in the future.
A user shared an 18-month update on their crown hair transplant, performed by Jason Sorgi at Boston Hair Restoration, expressing satisfaction with the results. They continue to use oral minoxidil and finasteride to maintain hair health.
The user has been taking dutasteride for 9 months and is satisfied with the hair growth results. They had a hair transplant and don't want to share hairline progress.
Hair loss discussion includes potential HMI-115 treatment. Topical mucuna pruriens shows good results, blocking prolactin possibly more important than blocking DHT.
Oral minoxidil dosing should be based on body weight to minimize side effects, with higher doses increasing risks like pericardial effusion. Combining oral minoxidil with topical treatments and finasteride can improve hair growth, but regular heart health monitoring is essential.
The conversation discusses using pumpkin seed oil and rosemary oil for hair thinning, with skepticism about their effectiveness compared to pharmaceutical options like finasteride and minoxidil. Some users suggest trying natural treatments, while others emphasize the proven success of pharmaceuticals.
VDPHL01 shows faster and stronger hair growth compared to standard minoxidil, with no major side effects reported. Users discuss combining it with other treatments like dutasteride and finasteride for better results, while expressing skepticism about the effectiveness of PP405.
To maintain hair regrowth, users suggest parting the hair to apply treatments like minoxidil and finasteride directly to the scalp. Consistent application is necessary to prevent hair loss from returning.
A 24-year-old male with diffuse thinning has been using finasteride for two years, dutasteride for 6-7 months, and oral minoxidil for 5 months, along with topical treatments. He plans to continue this regimen and reassess in August 2026, hoping to stabilize hair loss without surgery.
A user shared their success with 1mg daily finasteride, regrowing their crown hair significantly over 15 months without side effects. The user attributes their results to being a hyper responder and did not use minoxidil or other treatments.
The user added topical finasteride to their regimen of dutasteride and oral minoxidil, noticing a significant reduction in hair shedding after three weeks. They obtained the topical finasteride from a compounding pharmacy with a 0.25% concentration.
A user experienced increased hair shedding after 2.5 years on finasteride and 5 months on minoxidil, possibly due to recent additions like supplements and microneedling. Others shared similar experiences with minoxidil shedding, suggesting it may be a normal part of the process, with hair often growing back thicker.
A 20-year-old male is frustrated with his dermatologist for refusing to prescribe DHT blockers like finasteride or dutasteride, instead pushing for a hair transplant despite ongoing hair thinning. The user feels dismissed and unreasonably treated, and is advised by another user to find a better dermatologist and consider finasteride or dutasteride for effective treatment.
A 31-year-old experienced significant hair regrowth after switching to oral Finasteride but reported dull orgasms as a side effect. Users suggested waiting for the body to adjust, reducing the dosage, or switching to topical Finasteride to manage side effects.
The user experienced side effects from oral minoxidil and is seeking alternatives like Stemoxydine, Aminexil, and Redensyl + Procapil. They have been using finasteride for four years and are considering other treatments due to concerns about side effects.
A 23-year-old discusses their hair loss treatment using finasteride, dutasteride, oral and topical minoxidil, and topical tretinoin under medical supervision. They stress stabilizing hair loss before a hair transplant and plan to continue the regimen for at least 18 months.
PP405 is criticized for overhyped claims and cherry-picked data, with doubts about its effectiveness compared to minoxidil and finasteride. Many users express skepticism, emphasizing the need for more comprehensive trial results.
The user has been on finasteride for over two years, experiencing early hair regrowth, acne, and scalp sensitivity, but now faces thinning hair and questions about dosage and long-term effectiveness. They also used retinal to help with acne and are seeking advice on whether to adjust their finasteride dose.
The user experienced significant hair regrowth using oral Minoxidil, Finasteride, and Biotin over 8 months, with most growth between November and January. Despite some skepticism, the progress is notable, and the user plans to continue the treatment.
A 25-year-old is experiencing hair regrowth after six months of using oral finasteride, oral dutasteride, topical and oral minoxidil, microneedling, and keto shampoo. They report less shedding and healthier hair, with some side effects like GERD due to weight gain.
The user has used minoxidil for five years and added microneedling for four weeks without seeing results. They are considering a hair transplant but are advised that hair loss will persist without a DHT blocker.
A 22-year-old male experienced hair regrowth and improved hair health after using Minoxidil, Finasteride, and microneedling for nine months, with initial shedding but no significant side effects. Users discussed similar experiences with hair styling difficulties and shared tips for managing hair texture and side effects.
A 20-year-old has been using finasteride for a year and added minoxidil three months ago, seeing significant hair regrowth. They are considering continuing the current treatment or possibly a hair transplant in the future.
User is happy with 6 months of using finasteride 1mg, minoxidil 5%, and weekly microneedling, with no side effects. The post includes progress pictures.
User shared progress pictures after 5 months using 5 mg oral minoxidil, a topical formula with 8% minoxidil, 0.1% finasteride, and 0.01% tretinoin, and a 1.5 mm Dermapen every other week. The conversation discusses the effectiveness of this regimen for hair loss.
A user shared 3-month progress pictures using 1mg finasteride daily, reporting no side effects and planning to add oral minoxidil. Replies praised the results and questioned the need to add minoxidil.