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      community Pyrilutamide for 16 weeks, with some progress

      in Progress Pictures  40 upvotes 2 years ago
      User gained hair with topical minoxidil and finasteride, then experienced shedding after starting pyrilutamide. After 12 weeks, new hairs grew and existing hairs thickened, hoping for more improvement in a year.

      community Are 10% fluridil formulations effective?

      in Treatment  6 upvotes 2 years ago
      The user is asking if using a 10% fluridil formulation would be effective for blocking scalp androgens in addition to their current treatment of oral dutasteride.

      community 4.5 months of Dut/5% topical min

      in Progress Pictures  39 upvotes 1 year ago
      OP saw significant hair growth after starting scalp exfoliation and using 5% topical minoxidil for 4.5 months, along with microneedling initially. Users discussed the benefits of exfoliation and inquired about experiences with finasteride and dutasteride.

      community Saw Palmetto/Biotin/Minoxodil--my experience.

       9 upvotes 11 years ago
      The user experienced hair regrowth and reduced shedding using saw palmetto, biotin, minoxidil, fish oil, and Nizoral, but hair loss resumed after discontinuing the regimen. They are considering reintroducing the regimen and possibly trying finasteride.

      community If you gentlemen are balding like myself, I encourage you to try shaving.

      in Shaved/buzzed  1608 upvotes 1 year ago
      A user encouraged others experiencing hair loss to try shaving their heads, sharing their own positive experience despite briefly using finasteride and natural methods. Responses were mixed, with some supporting the decision and others suggesting treatments like minoxidil and finasteride, while many commented on the appearance changes.

      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  8 upvotes 3 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

      community Fluridil (Eucapil) seems like a great option?

      in Treatment  4 upvotes 5 months ago
      The user stopped using finasteride due to side effects and is considering Fluridil (Eucapil) as an alternative for hair loss treatment. They are exploring other options like RU58841 and are interested in the experiences of others with Fluridil, noting its good safety profile despite the cost.

      community Combining Microneedling with LLLT

      in Research/Science  13 upvotes 1 year ago
      Combining microneedling with Low Level Laser Therapy (LLLT) for hair growth, with discussions on device legitimacy and effectiveness. Alternatives like PEMF and the use of oral and topical treatments such as dutasteride, minoxidil, and finasteride are also considered.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community The best vehicle/carrier for RU58841

      in Treatment  2 upvotes 2 years ago
      The conversation is about the best vehicle for RU58841, comparing trichosol and Garnier/Vichy Stemoxydine, avoiding propylene glycol (PG) or ethanol due to previous scalp damage. The user is also seeking sources for these products in the EU.

      community Monthly Reminder.

       10 upvotes 7 years ago
      Various treatments for male pattern baldness including Minoxidil, Finasteride/Dutasteride, hair systems, and oral anti-androgens such as Spironolactone and Flutamide. It also mentions dermarolling as a possible treatment in conjunction with minoxidil.

      community Has anyone had success with lipodermal solution?

      in Finasteride/Dutasteride  1 upvotes 8 months ago
      The conversation discusses using a lipodermal solution for hair loss, with concerns about side effects from multiple active ingredients. Users mention experiences with minoxidil, finasteride, and dutasteride, noting side effects like brain fog and sexual issues.

      community How did you all stop the itching that occurs where you are balding?

      in Treatment  17 upvotes 1 year ago
      People discussed solutions for scalp itching related to hair loss, with treatments including finasteride, dutasteride, ketoconazole shampoo, and Alpecin Hybrid shampoo. Some users found relief by adjusting dosages of finasteride or switching to dutasteride, while others recommended specific shampoos or prescription options like olux foam.

      community minoxidil and tretinoin usage

      in Minoxidil  5 upvotes 1 year ago
      The user is using minoxidil, finasteride, and recently added tretinoin to address hair loss, specifically around a receding hairline. They are seeking advice on application methods and mention experiencing mild skin rashes potentially from tretinoin.

      community I hope ET-02 or PP405 will be released in the next 4-5 years

      in Product  15 upvotes 11 months ago
      PP405 is a potential hair loss treatment that may work by blocking signals that cause hair cells to stop growing, requiring daily application for effectiveness. It could serve as an alternative to minoxidil and finasteride, but it is not yet available on the market and may take several years to be released.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

      in Treatment  30 upvotes 4 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community Anyone here used spirolactone/cyproterone acetate/bicalutamide?

      in Chat  5 upvotes 8 months ago
      The conversation discusses the use of spironolactone, cyproterone acetate, and bicalutamide for hair loss, with concerns about side effects like gynecomastia and depression. Topical spironolactone is considered safe for men and effective when combined with regular treatments.

      community Pyrilutamide just launched internationally, and all you're doing is hating

      in Product 1 year ago
      The post and conversation are about the high cost and skepticism surrounding pyrilutamide as a hair loss treatment, with comparisons to minoxidil, finasteride, and RU58841. The original poster defends pyrilutamide's effectiveness and criticizes others for dismissing it without proper understanding.