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GlossaryDepilatory Creams

chemical lotions that dissolve hair for easy removal

Depilatory creams, also known as hair removal creams, are topical products designed to remove unwanted hair from the skin's surface. They contain active chemical ingredients, such as calcium thioglycolate or potassium hydroxide, which break down the protein structure of hair, making it easy to wipe away. These creams offer a painless alternative to shaving or waxing and are commonly used for areas like the legs, arms, and face.

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community Keratin microspheres - breakthrough

in Research/Science 14 upvotes 2 years ago

A gel of keratin microspheres promotes hair follicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.

community RESULTS: 1% Clascoterone Cream. (3 months Jan-Mar 2026)

in Progress Pictures 15 upvotes 2 months ago

The user reported slight improvement in hairline using 1% Clascoterone cream over three months but found it too costly to continue. They expressed interest in trying a 5% concentration if it becomes available at a reasonable price.

community Facial hair loss

in Treatment 5 years ago

User noticed beard and sideburn hair loss, and thinning eyebrows, diagnosed with alopecia barbae and male pattern baldness, and prescribed Desonide cream. User seeks feedback on Desonide cream.

community DHT Gel (2.5%) to beard area + Dut + Pyri 1% + Minox

in Research/Science 5 upvotes 8 months ago

The conversation discusses using a combination of DHT gel, dutasteride, pyrilutamide, and minoxidil to promote beard growth while minimizing hair loss. Users suggest consulting a doctor and considering genetic factors before proceeding.

community Topical androgens for alopecia to treat sebum overproduction on the face

in Product 1 upvotes 2 years ago

The conversation discusses using scalp antiandrogens like RU58841, pyrilutamide, or fluridil on the face to reduce sebum production, noting that clascoterone (winlevi) is an approved facial antiandrogen with underwhelming reviews.

community Trichosol, polyethylene glycol, and DMSO

in Minoxidil 3 upvotes 2 years ago

The user experiences irritation from alcohols in minoxidil and is considering alternatives like trichosol mixed with polyethylene glycol or DMSO. They seek advice on the best nonirritating option.

community Can using styling products like wax/clay and powders effect absorption of topical treatments?

in Product 2 upvotes 2 years ago

A user is using Fluridil for hair loss and is concerned that styling clay and powder might affect the absorption of the treatment. They apply clay in the morning and Fluridil in the evening and are considering switching to a styling powder.

community Unwanted hair growth from minoxidil

in Progress Pictures 57 upvotes 9 months ago

Unwanted hair growth from minoxidil use, with suggestions to reduce dosage or switch to finasteride. Users recommend hair removal methods like shaving, waxing, or electrolysis to manage excess facial hair.

community cb-03-01 research chem (winlevi/clascoterone cream)

in Technology 3 upvotes 2 years ago

The user is considering using CB or clascoterone for hair loss, potentially as an alternative to RU. They're also contemplating asking a dermatologist for topical clascoterone cream to apply to their temple.

community Question about clascoterone acne cream

in Treatment 2 upvotes 1 month ago

Clascoterone cream can be used on the scalp, but it may not be effective due to its dosage. AR antagonists like clascoterone are generally less effective than 5AR inhibitors for hair loss.

community Does Fluridil reducing shedding?

in Product 6 upvotes 2 years ago

Eucapil (fluridil) may reduce hair shedding. It can be added to a regimen with finasteride and minoxidil.

community DHT is required to convert vellus hair into terminal hair?

in Finasteride/Dutasteride 1 upvotes 1 year ago

Finasteride and Dutasteride block DHT, which is needed for vellus hair to become terminal on the beard but not on the scalp. The user considered using DHT cream but learned it's unnecessary for scalp hair.

community If pp405 isnt the “cure” is there anything else that’s promising thats atleast better than min or dut?

in Chat 19 upvotes 2 months ago

Hair cloning and new treatments like ET-02, Veradermics (vdphl01), and wound-induced hair neogenesis show promise but are not yet widely available. Current effective treatments include minoxidil, finasteride, and dutasteride, with early intervention being crucial for better outcomes.

community Pelage are starting phase 3 for PP405 towards the end of 2026

in Chat 180 upvotes 4 months ago

PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

community how about progesterone cream?

in Research/Science 22 upvotes 2 years ago

Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

community Dry flakes from topical fin use

in Finasteride/Dutasteride 2 upvotes 1 year ago

The user is experiencing white flakes and a greasy look from using a topical solution containing 0.025% finasteride, 8% minoxidil, 0.01% retinoic acid, and 1% hydrocortisone. Suggestions include reducing application frequency, using a brush to clean the scalp, and considering alcohol-free alternatives.

community Pyrludimide (KX-826) or Breezula (clascoterone)

in Treatment 9 upvotes 2 months ago

The conversation is about hair loss treatments, specifically Pyrludimide (KX-826) and Breezula (clascoterone), with the user unable to tolerate finasteride and dutasteride. The user plans to use these treatments alongside minoxidil, considering the efficacy and availability of each option.

community What do you think about this galenic lotion by my trichologist?

in Hair Systems 2 upvotes 1 year ago

The user discusses a galenic hair lotion containing progesterone, estradiol, cyproterone, hydrocortisone butyrate, and cetirizine pheniramine, which has effectively stopped their hair loss over two years. They are curious about the compatibility of finasteride with the lotion's components and note that their trichologist has successfully used minoxidil and finasteride in similar treatments for others.

community Is fluridil cost-efficiency absolute garbage?

in Product 1 upvotes 2 years ago

Fluridil is considered safe with moderate effectiveness for hair loss, but its cost of €50 per month is seen as high compared to other treatments. The user is considering Pyri as a more cost-effective option and is seeking success stories about Fluridil's ability to stop hair loss without side effects.

community making a clascoterone lotion from powder

in Technology 2 upvotes 1 year ago

A user is considering making a 2% clascoterone lotion from powder due to unavailability in their location. They plan to mix clascoterone powder with retinol lotion and use literature to determine the correct dosage.

community scarring alopecia awareness in this community

in Chat 33 upvotes 3 years ago

Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

community Minoxidil hack PSA for you all

in Treatment 59 upvotes 1 year ago

Switching from liquid to foam Minoxidil to avoid scalp irritation, with a method to melt the foam for easier application. Users discuss alternatives and personal experiences with Minoxidil, including issues with propylene glycol and different application methods.

community Do any shampoos contain Piroctone Olamine in the US

in Product 3 upvotes 1 year ago

The conversation is about finding shampoos with Piroctone Olamine in the US for itch relief, as the user has not found relief with Keto shampoo, oral Dutasteride, and oral Minoxidil. Users suggest alternatives like Neutrogena T/Gel and online options, but note availability and price issues.

community Topical Finasteride -- Without Propylene Glycol (PG)

in Finasteride/Dutasteride 2 upvotes 5 years ago

The user seeks alternatives to Propylene Glycol (PG) for delivering topical finasteride due to scalp irritation. They consider using Propanediol 1,3 and ask for other suggestions.

community Anyone used Topical Calcipotriol (cream) or VPA ( Valproic Acid)

in Chat 9 upvotes 5 years ago

The conversation discusses using topical Calcipotriol and Valproic Acid for hair loss, focusing on their mechanisms involving the VDR receptor and Wnt/beta-catenin pathway. Specific treatments mentioned are Minoxidil, Finasteride, and RU58841.

community Hair repigmentation of poliosis circumscripta in androgenetic alopecia patient treated with exosomes and fractional picosecond laser

in Product 2 upvotes 2 years ago

Exosomes combined with fractional picosecond laser treatment were effective in treating androgenetic alopecia and promoting repigmentation in white hair patches. The role of exosomes in hair repigmentation, particularly in conditions like poliosis, is not well-studied.

community Swapping from Fluridil to Pyrilutimide?

in Treatment 1 upvotes 4 months ago

The conversation discusses hair loss treatments, with the main focus on using Fluridil and considering switching to Pyrilutamide. Other treatments mentioned include minoxidil, topical finasteride, nizoral shampoo, and saw palmetto supplements, with advice to stick with Fluridil for at least six months before considering alternatives.

community Fluridil vs Breezula?

in Treatment 15 upvotes 5 years ago

Comparing two upcoming topical hair loss treatments, Fluridil and Breezula, to determine which is most effective for treating hair loss, taking into consideration factors such as price, side effects, potential for hair growth, convenience of application, smell, greasiness, and styling after use.

community Does anyone know of the actual effectiveness of the DP2 inhibitors?

in Question 4 upvotes 8 years ago

Setipiprant and Fevipiprant are questioned for their effectiveness in hair maintenance, with skepticism due to lack of convincing results beyond vellus hair growth. The user is satisfied with Minoxidil and Finasteride but is curious about the potential of DP2 inhibitors.

community topical finasteride: dissolving finasteride in "alpacin cafeine liquid"?

in Finasteride/Dutasteride 1 upvotes 2 years ago

A user discusses using Alpecin Caffeine Liquid for scalp health and considers dissolving finasteride tablets into it for a DIY topical treatment. They inquire about potential absorption issues with this method.