The conversation discusses the use of microneedling for hair loss, with concerns about potential long-term effects like fibrosis and scarring. Users share experiences and opinions on combining microneedling with treatments like minoxidil and finasteride, but there is uncertainty about the long-term safety and efficacy.
A user experienced significant hair growth using oral dutasteride and minoxidil but developed severe erectile dysfunction, likely exacerbated by obesity and diabetes. They plan to lose weight and possibly adjust medication to alleviate sideeffects.
Topical dutasteride, particularly at 0.05%, shows greater hair density improvement than oral finasteride over 24 weeks, though hair thickness gains are similar. Some users report sideeffects with topical treatments, but others find them effective for maintaining hair without significant systemic absorption.
The user experienced sideeffects from RU58841, including dry eyes and potential eyesight issues, and decided to stop using it. They confirmed the product's legitimacy but advised caution due to its experimental status and lack of safety data.
Increased scalp itching during shedding phases while on finasteride treatment may coincide with hair regrowth and recovery. This suggests that itching might not always indicate continued hair loss and could encourage persistence with the treatment.
The post and conversation discuss whether Minoxidil causes facial aging, with some users reporting no sideeffects and attributing negative effects to possible allergic reactions. The original poster suggests more research is needed to confirm any connection between Minoxidil and facial aging.
The conversation is about choosing a topical antiandrogen for hair loss, with options including RU58841, CB0301, Pyrolutamide, Alfatradiol, and Fluridil. Users discuss their preferences and reasons for selecting specific treatments.
A user is starting topical finasteride and minoxidil 3 times a week for hair loss and is experiencing high anxiety about the treatment's effectiveness and potential sideeffects. They are also taking vitamin D3 daily and are concerned about the application method and possible shedding.
Finasteride can aid hair regrowth but may cause sideeffects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.
The user reported slight improvement in hairline using 1% Clascoterone cream over three months but found it too costly to continue. They expressed interest in trying a 5% concentration if it becomes available at a reasonable price.
Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.
The conversation discusses treatments for androgenetic alopecia, focusing on evidence-based supplements to complement finasteride. Suggestions include oral minoxidil, saw palmetto, pumpkin seed oil, tocotrienols, and various other supplements, while emphasizing the importance of scientific backing and cautioning against saw palmetto if already using finasteride.
PP405 from Everychem is likely fake and potentially harmful, with concerns about its stability and the risk of using the wrong MPC inhibitor, which could damage hair follicles. The real PP405 was studied under strict conditions, and DIY attempts are discouraged due to unknown formulation and quality control.
The user experienced significant hair regrowth after starting oral minoxidil (2.5mg) and dutasteride (0.5mg) daily, and is considering resuming microneedling at home with a dermapen. They are concerned about potential risks of microneedling, such as scarring, and are seeking advice on needle length and frequency.
The user experienced significant hair shedding and an itchy scalp after using a combination of Finasteride, Dutasteride, and Minoxidil. They are seeking advice on whether Dutasteride might be causing these issues and are considering adjusting their treatment regimen.
User discusses hair loss treatment progress using Dutasteride for 2 years, RU58841 for 5 months, and oral Minoxidil for 1 year. Some users share sideeffects and experiences with these treatments.
The user experienced initial hair regrowth with topical dutasteride and minoxidil but later faced significant hair shedding, leading to doubts about the effectiveness of topical dutasteride. They plan to continue the treatment for a year and may switch to oral finasteride if no improvement is seen.
The conversation discusses whether age affects the sideeffects and effectiveness of hair loss treatments like finasteride and dutasteride. Some believe early treatment yields better results, while others mention varied outcomes across ages and personal regrowth experiences without a clear consensus on age impact.
Switching from finasteride and topical minoxidil to oral dutasteride and oral minoxidil can cause initial hair shedding, but many users report improvement after a few months. Opinions vary on whether to taper off or switch directly, with some suggesting gradual changes to monitor sideeffects.
A user switched from finasteride to dutasteride due to sideeffects and saw significant hair improvement after 7 months, with no sideeffects from dutasteride. They also switched from topical to oral minoxidil, which may have contributed to the positive results.
The user is experiencing thicker hair after using oral minoxidil, dutasteride, biotin, collagen shampoo with rosemary, and ketoconazole. They are considering adding a derma roller to their regimen for potential benefits.
The conversation discusses the need for a localized 5-alpha reductase inhibitor that only affects the scalp without systemic sideeffects, similar to pyrilutamide's approach. Current treatments like topical liposomal finasteride and dutasteride are mentioned, but concerns about their systemic effects and lack of research are highlighted.
The user is using 5% topical minoxidil, tretinoin 0.05% cream, and weekly derma rolling for early-stage male pattern baldness and has seen some progress. They prefer not to use finasteride or dutasteride due to potential sideeffects.
A dermatologist advised stopping oral Minoxidil for a 19-year-old and suggested a topical mix with Minoxidil, Finasteride, Tretinoin, and Melatonin, while continuing oral Finasteride. The user is curious about the effectiveness and sideeffects of switching to Dutasteride compared to the topical mix.
The user is struggling with seborrheic dermatitis and plans to try ciclopirox olamine after finding ketoconazole too drying. They are also using finasteride daily.
The user experienced redness and itching from using 5% minoxidil and is considering trying a lower dose or alternative treatments like 2% minoxidil, mesotherapy, PRP, or rosemary oil. They are seeking advice on managing sideeffects and exploring other options for hair stimulation.
A user shared their experience using Dutasteride for hair loss, alongside a regimen of Minoxidil, Finasteride, and RU58841. They reported no major shedding or sexual sideeffects, but experienced mild acne when increasing the Dutasteride dose, and noted their hair condition remained stable.
Dutasteride at 2.5 mg/day reduces scalp DHT by 80%, while 0.5 mg/day reduces it by 50%, with minimal difference in sideeffects. Users often combine it with finasteride, RU58841, and minoxidil for better hair loss management, though sideeffects like dry skin and pimples are noted.
The conversation is about finding a safe carrier for topical antiandrogens like finasteride, kx-826, RU58841, and dutasteride to minimize systemic absorption and sideeffects. The user experiences sideeffects from these treatments and is seeking advice on carriers that reduce these effects.