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GlossaryDermal-Epidermal Junction

interface where the epidermis connects to the dermis

The Dermal-Epidermal Junction (DEJ) is a critical area of skin where the outer layer (epidermis) connects to the underlying layer (dermis). This junction plays a vital role in maintaining skin integrity, facilitating nutrient exchange, and supporting cellular communication. It is essential for wound healing and overall skin health, and its degradation can lead to various skin disorders.

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community Another molecular pathway to promote scarless healing and regenerate hair follicles

in Research/Science 13 upvotes 3 months ago

Carnosic acid in rosemary extract may enhance skin repair and promote hair follicle regeneration. It could be used alone or with verteporfin for scarless healing after dermal wounding.

community Sup Chooms?! How y’all living?!

in Progress Pictures 973 upvotes 1 year ago

A 35-year-old shared their 5-month hair regrowth progress, using 0.5mg oral finasteride daily, topical minoxidil/finasteride once daily, derma stamping 1-3 times a week, washing hair daily or every other day with peppermint soap, and using eczema lotion for scalp health. Commenters congratulated the individual on the significant improvement in their hairline.

community Microneedling must reach the stem cells in the upper hair shaft

in Treatment 79 upvotes 4 years ago

Microneedling should target depths of 0.5mm to 1.5mm for hair loss, with weekly sessions at 1mm recommended. Combining microneedling with Minoxidil is common for improved results.

community What Are the Technicalities of Curved Hair Transplantation?

in Transplants 5 upvotes 2 weeks ago

Curved hair transplantation requires specialized tools and techniques to avoid damaging hair follicles, with modified FUE being the preferred method. Proper extraction and implantation angles are crucial to prevent complications like keloids and sterile folliculitis.

community M32, almost 3 moths, fin oral 1,25g/daily + min 2xday + keto 2% shapoo 1/week microneedling once a week

in Progress Pictures 31 upvotes 2 years ago

A 32-year-old man has been treating his hair loss with daily oral finasteride (1.25g), twice-daily topical minoxidil, weekly ketoconazole 2% shampoo, and weekly microneedling for almost three months, with no side effects from finasteride. He started with a Hamilton Norwood scale rating of 5 and has seen improvement without experiencing pain by using a 0.8mm needle length for microneedling.

community Sharing my 3.5 year journey, keep grinding guys

in Progress Pictures 228 upvotes 1 year ago

The user shared a 3.5-year hair loss treatment journey using 1 mg finasteride daily and minoxidil foam, noting significant improvement, especially in the third year. They also mentioned using Nizoral shampoo twice a week and supplements like vitamin D3, biotin, and omega 3 and 6.

community TCA 35% chemical peel, don't try this shit at home.

in Treatment 11 upvotes 1 month ago

The conversation discusses using a TCA 35% chemical peel on the scalp to potentially improve hair growth by addressing fibrosis and enhancing the effectiveness of topical treatments. The user also mentions trying microneedling and other methods like topical metformin and dutasteride for hair regrowth.

community My dermatologist screwed me over methinks (18M)

in Minoxidil 12 upvotes 1 year ago

A user discusses their hair thinning journey, starting minoxidil at 16, switching treatments, and experiencing significant shedding after resuming minoxidil. They are now using minoxidil daily and considering PRP if shedding continues, while also planning lifestyle changes to improve their condition.

community 4 months M26 Fin/Min/Keto/microneedle

in Progress Pictures 39 upvotes 2 years ago

A 26-year-old male shared progress pictures after 4 months of treating hair loss with finasteride (1.25 mg on Mondays, Wednesdays, and Fridays), topical minoxidil twice daily, ketoconazole shampoo twice weekly, and weekly microneedling at 1.5 mm. He is seeing hair growth improvement, especially in the front, and is considering hair grafts for the crown area if necessary for more density.

community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

in Chat 55 upvotes 2 years ago

The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.

community New Light Therapy Can Suppress a Key Marker of Hair Loss by 92%

in Research/Science 201 upvotes 1 week ago

A new light therapy claims to reduce hair loss markers by 92% using a specific wavelength range. Users discuss the cost and effectiveness of devices, with some expressing skepticism and others considering alternative treatments like red light therapy and vitamin D exposure.

community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

in Research 830 upvotes 1 year ago

Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

community Fin/min/microneedling ~9 months – no results, actually worse

in Progress Pictures 96 upvotes 2 years ago

User harlital shared their 9-month hair loss journey using finasteride, minoxidil, and microneedling but experienced worse results. Commenters suggested patience, checking for other causes, and considering dutasteride after 12-24 months if no improvement.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 43 upvotes 6 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community Last Post Before I Switch Back to Finasteride From Dutasteride

in Finasteride/Dutasteride 29 upvotes 1 year ago

The user plans to switch from dutasteride back to finasteride due to worsening hair loss, possibly due to increased scalp testosterone. Others report mixed results with both treatments, showing individual variability.

community Why do I see so many people here recommend microneedling?

in Microneedling 108 upvotes 3 years ago

The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.

community The Fear of Oral Minoxidil is Overblown

in Research/Science 272 upvotes 9 months ago

Low-dose oral minoxidil is a safe and effective hair loss treatment with fewer side effects than previously feared. Users often prefer it over topical minoxidil for better results, though some experience side effects like increased body hair and cardiovascular issues.

community Alright boys, who’s willing to burn their scalp for science?

in Research/Science 765 upvotes 3 years ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community Hope for older men! 57 year old male 6 mo. progress pics. Minoxidil, RU58841, Microneedling, Nizoral

in Progress Pictures 27 upvotes 3 years ago

A 57-year-old man shared his 6-month hair regrowth progress using RU58841, Minoxidil, microneedling, and Nizoral. He experienced significant improvement, with a smaller bald spot, thicker hair, and hairline regrowth.

community Comprehensive Microneedling Guide

in Microneedling 288 upvotes 3 years ago

Microneedling for hair restoration involves daily use of a 0.3 mm device and weekly use of a 0.5 mm device. Combining microneedling with Minoxidil can enhance hair growth.

community I started rapidly diffuse thinning at 22. I'm 42 now and have as much hair as I did at 16. AMA

in Treatment 443 upvotes 6 years ago

Hair loss treatments like finasteride, minoxidil, ketoconazole, PRP, and microneedling helped maintain hair for 20 years. Research and try evidence-based treatments for best results.

community Summary of Procapil video by Haircafe

in Minoxidil 2 upvotes 9 months ago

Procapil is marketed as a natural hair loss treatment but lacks strong evidence and is industry-biased. Minoxidil and Finasteride are the only FDA-approved treatments for androgenetic alopecia.

community If you aren't happy with your results but haven't tried microneedling: why not?

in Microneedling 363 upvotes 10 months ago

Microneedling with minoxidil significantly boosts hair growth, even for non-responders to minoxidil alone. The routine includes a 1.5mm dermaroller weekly and minoxidil twice daily, with some users adding finasteride and tretinoin.

community Are Derma Rollers Actually Harmful in the Long Run?

in Microneedling 40 upvotes 1 year ago

Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

community My microneedling journey (no min, fin, etc)

in Microneedling 210 upvotes 1 year ago

The user experienced positive hair growth results using microneedling with rosemary and mint oil, without Minoxidil, Finasteride, or RU58841. They switched from a dermaroller to a microneedling pen and targeted different scalp areas weekly.

community 2 months of 1mg Finasteride daily , %5 minoxidil 2x daily, Nizoral Shampoo and 1.5mm depth microneedling weekly

in Progress Pictures 228 upvotes 1 year ago

A user shared progress pictures after using 1mg Finasteride daily, 5% Minoxidil twice daily, Nizoral Shampoo, and weekly microneedling at 1.5mm depth for two months, reporting no side effects and discussing their routine and supplements. Commenters reacted positively, with one advising caution with creatine and another endorsing the benefits of microneedling.

community Why nobody uses 0.25% (2.5mg/ml)?

in Treatment 66 upvotes 2 years ago

The conversation is about the effectiveness of 0.25% topical finasteride compared to other concentrations and forms. Users discuss its potential for better scalp DHT reduction and fewer side effects, with some preferring topical over oral treatments.

community Vitamin C and hair growth PH levels

in Product 34 upvotes 4 years ago

The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.

community Derms are so useless, how did they even get to be in these positions with all these academic years when random internet dwellers know more than them?

in Chat 100 upvotes 3 years ago

The conversation is about frustration with dermatologists not effectively treating hair loss and the difficulty in obtaining prescriptions for Minoxidil and Finasteride. Some users suggest seeing specialists or general practitioners for hair loss treatment, while others share their own experiences with dermatologists and the importance of doing personal research.

community 5 Month Progress. Fin/Min/Niz/Derm

in Progress Pictures 538 upvotes 4 years ago

User "yungnickyyp" shares 5-month progress using Fin/Min/Niz/Derm for hair loss. Others express jealousy and amazement at the significant hair regrowth.