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    GlossaryDesert Hedgehog

    gene involved in hair follicle development and cell differentiation

    Desert Hedgehog (DHH) is a gene that encodes a signaling protein involved in the development of various tissues, including hair follicles. It plays a crucial role in the regulation of cell growth and differentiation, particularly in the formation of the dermal papilla, which is essential for hair follicle development and cycling. Mutations or disruptions in the DHH gene can lead to hair growth disorders and contribute to conditions like alopecia.

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      community Minoxidil Storage Conditions in Summer

      in Research/Science  5 upvotes 10 months ago
      Store minoxidil and minoxidil+finasteride solutions in a cool environment, ideally below 25°C, to maintain effectiveness. Consider using a wine cellar or fridge for stable, low temperatures.

      community 42 male - 8 months (Is this the biological limit?)

      in Progress Pictures  58 upvotes 2 weeks ago
      A 42-year-old male has reached a plateau in hair regrowth after 8 months using Dutasteride, Minoxidil, a dermaroller, and Ketoconazole. Suggestions include continuing treatment, considering a hair transplant, and improving nutrition.

      community I think this is my stop, gentlepeople. So long and thanks for all the data 👋

      in Transgender  2263 upvotes 9 months ago
      A user shared their successful experience with hair regrowth and transitioning from male to female using minoxidil, finasteride, Nutrafol, microneedling, and hormone replacement therapy (HRT). They expressed gratitude for the results and encouraged others to explore treatments that align with their personal goals.

      community 100 days of Fin/Min/Biotin/Saw Palmetto

      in Progress Pictures  400 upvotes 1 year ago
      The user shared impressive hair growth results after 100 days using finasteride, minoxidil, biotin, and saw palmetto, and plans to get a hair transplant. The conversation includes suggestions for additional treatments like ketoconazole and derma stamping, and discussions about potential side effects of finasteride.

      community nutrafol actually working somehow??

      in Update  19 upvotes 1 year ago
      A user reports significant improvement in scalp thinning after nearly 2 months of using Nutrafol, along with derma rolling and weekly rosemary oil application. Another user suggests the success might be due to saw palmetto in Nutrafol and shares their own experience of maintaining hair without finasteride.

      community Further prolactin research....

      in Research/Science  6 upvotes 2 years ago
      HMI 115 did not work as expected for hair regrowth in humans, unlike in macaque monkeys. There is anticipation for further research on prolactin's role in hair loss, with expectations that pharmaceutical companies will likely solve this before universities.

      community Update: 16 months deep - big 3

      in Progress Pictures  407 upvotes 2 years ago
      The user has seen positive results after 16 months of using topical Finasteride/Minoxidil, microneedling weekly, and Tretinoin for hair loss. There are no reported side effects, and the user advises that the effectiveness of microneedling depends on the pressure applied.

      community 6 Months on Min & Fin Question

      6 years ago
      After 6 months on Minoxidil and finasteride, the user sees minimal new hair growth and questions if it's a sign of slow progress or ineffectiveness. Another user suggests maximum improvement with these treatments can take up to 2 years.

      community Can a THICK and DENSE beard partially compensate esthetically MPB

      in Styling  3 upvotes 2 weeks ago
      A 20-year-old experiencing hair loss is using minoxidil and ketoconazole shampoo but had to stop finasteride due to side effects. They are considering a hair transplant and debating whether a thick beard can compensate for hair loss in terms of attractiveness.

      community [rant] being hairless is ruining all my self esteem

      in Chat  174 upvotes 4 days ago
      Hair loss is causing distress and self-esteem issues, with discussions on treatments like finasteride, minoxidil, and hair transplants. Some suggest topical treatments or lifestyle changes, while others stress the importance of confidence and self-acceptance.

      community 3 surgery total 7600 Grafts surgery journey

      in Progress Pictures  725 upvotes 1 month ago
      A person had three hair transplant surgeries using 7,600 grafts from scalp, beard, and chest, along with finasteride and minoxidil. Reactions are mixed, with suggestions for alternatives like hair systems or scalp micropigmentation.

      community I was very very very very very very very very wrong

      in Ketoconazole  48 upvotes 5 months ago
      Nizoral, a ketoconazole shampoo, can cause scalp dryness and hair shedding if overused. Users discuss alternatives like Selsun Blue, finasteride, and dutasteride for managing hair loss and seborrheic dermatitis.

      community Why do we get bald from evolutionary perspective

      in Chat  213 upvotes 9 months ago
      Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.

      community Two months of minoxidil 5mg only!

      in Progress Pictures  197 upvotes 10 months ago
      The conversation discusses hair loss treatments, specifically the use of minoxidil and the potential addition of finasteride. The user has seen some progress with minoxidil but is hesitant about finasteride due to possible side effects, while others suggest combining both for better long-term results.

      community Month 7. Dut/min/stemoxydine/microneedle. Nw7.

      in Progress Pictures  172 upvotes 1 year ago
      A user shared their 7-month progress on hair regrowth using a regimen of dutasteride, minoxidil, stemoxydine, microneedling, and keto shampoo. They noted significant improvement, particularly in vellus hair growth, and discussed the potential addition of RU58841, though they experienced side effects with it previously.

      community 6 Month Progress Update - Long Journey

      in Progress Pictures  472 upvotes 1 year ago
      Significant hair regrowth was achieved over six months using minoxidil, finasteride, microneedling, biotin and collagen shampoo, and MSM powder. The user feels more confident and may consider a hair transplant if necessary.

      community 4 months min/fin progress. Hopeful

      in Progress Pictures  270 upvotes 1 year ago
      A 19-year-old reports positive hair regrowth using oral minoxidil and finasteride, with no side effects. The conversation includes advice on consulting a dermatologist and exploring alternative treatments.

      community my gains after 7 months (nuclear stack)

      in Progress Pictures  1914 upvotes 1 year ago
      The user shared impressive hair growth results after 7 months using a regimen of dutasteride, topical minoxidil, and biotin, alongside a healthy lifestyle. The conversation humorously discusses extreme and unconventional hair loss treatments, with many users expressing amazement and curiosity about the progress.

      community Is this good improvement? 3-4 months in

      in Is this regrowth?  479 upvotes 1 year ago
      The user experienced increased hair density and thickness after 3-4 months using finasteride, minoxidil, dermastamping, ketoconazole, and biotin. They apply minoxidil right after dermastamping without any side effects or shedding.

      community 1 year progress with top. min & fin + dermastamp

      in Progress Pictures  2863 upvotes 1 year ago
      A user shared their 1-year hair regrowth progress using topical minoxidil and finasteride, biotin, dermastamping, and keto shampoo. They reported significant improvement, looking younger, and feeling happier with their hair.