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PP405 shows promise for hair follicle reactivation with minimal side effects. Users recommend continuing Minoxidil and Finasteride until more results are confirmed.

A 28-year-old is experiencing hair loss despite using treatments like oral minoxidil, finasteride, and high-dose dutasteride (2.5 mg). They suspect lichen planus might be contributing to the issue and plan to continue treatment while monitoring progress.

Switching from finasteride to dutasteride as a treatment for hair loss, with advice given that titrating up to daily use is optimal and results may be seen after one year. Additionally, the user mentioned adding topical minoxidil 5% which has produced good results.

The user reported positive progress in hair growth using Dutasteride 0.5 mg, Minoxidil 5%, and microneedling over 3.5 months. They plan to continue and improve their regimen for better results.

A user shared progress on hair regrowth using 5mg oral minoxidil and 0.5mg oral dutasteride daily, noting small hair growth and no significant side effects except bushier eyebrows. The conversation includes encouragement, personal experiences with hair loss treatments, and discussions on the effectiveness of microneedling.

The user received trichotest results indicating finasteride is ineffective for them, and they plan to use dutasteride mesotherapy and add cetirizine to minoxidil. They seek advice on incorporating dutasteride into their regimen.

The user reported improved hair density using Dutasteride 0.5mg and Oral Minoxidil 3.75mg, along with Nizoral shampoo and oils. There was debate about the validity of the progress due to differences in lighting and angles in the photos.

The post discusses using a combination of Dutasteride, Minoxidil, Ketoconazole, Estradiol, and Spironolactone for hair regrowth. Users suggest it needs more time and possibly a transplant, with some sharing personal experiences and side effects of similar treatments.

The user has been using finasteride and minoxidil for hair loss but experienced worsening temple recession. They suspect they might be more sensitive to testosterone and are considering trying RU58841 or CB 03 01 as additional treatments.

The user is experiencing hair regrowth after using 0.5mg dutasteride daily, 8% topical minoxidil twice daily, 2.5mg oral minoxidil daily, a 1.5mm derma stamp weekly, and keto shampoo 2-3 times weekly for two months. The progress is considered good, though there is a concern about scalp inflammation.

The conversation discusses using topical dutasteride with a dermapen for hair loss treatment. The user is deciding between liposomal and mesosomal formulations for this purpose.

A 28-year-old experiencing worsening hair loss despite using Dutasteride and oral Minoxidil is considering exosome therapy and possibly switching treatments due to side effects. They seek advice on whether to continue with Dutasteride or try alternatives like Pyrilutamide or topical supplements.

The user experienced significant hair regrowth using 0.5 mg Dutasteride and 5 mg oral Minoxidil daily, after initially using finasteride and a lower dose of Minoxidil. They are considering dermarolling or derma stamping to improve results further before opting for a hair transplant.

Despite using 5% minoxidil, 0.1% finasteride, and other treatments like microneedling, MK-677, and Cialis, hair loss continues with high testosterone and DHT levels. Considering oral dutasteride but concerned about further increasing testosterone levels.

The user started taking oral 0.5 mg dutasteride and 2.5 mg minoxidil daily since July 9. After about three months, they report positive progress in hair regrowth, with others agreeing it looks good.

User discusses group buy for finerenone, a third-gen mineralocorticoid antagonist for hair loss treatment. Finerenone inhibits TGFb, NOX, and ROS, and improves renal and cardiac function; topical dose should be no more than 10mg per day.

Hair density improved using topical dutasteride, minox, keto, and 3.5% fluridil for 6 months. Better results when hair is dry, but still unsatisfied when wet.

A user's 18-month progress on their hair loss treatment regimen, which includes 5mg oral minoxidil, 1.5mm microneedling with a pen once weekly, and 0.5mg/day dutasteride; other users noted the positive effects of finasteride and dutasteride in reducing DHT levels.

A 22-year-old male shares his 2-month progress using a regimen of 0.5mg dutasteride daily, 1.5mm dermarolling weekly, a daily multivitamin, and a topical serum with 10% minoxidil and 0.1% finasteride. He reports impressive hair regrowth, especially at the hairline, and has experienced no sexual side effects.

Blocking DHT may slow down aging and improve skin, with users reporting positive effects from finasteride. Minoxidil and RU58841 are also mentioned as treatments.

Microneedling can cause sneezing and eye tearing due to nerve stimulation, particularly near the temples and forehead. Some users find it lessens over time, while others prefer using finasteride and minoxidil for hair growth.

A user shared their 7-month progress using 1mg daily Dutasteride and 2.5-5mg daily oral Minoxidil for diffuse unpatterned alopecia, showing significant hair regrowth with reduced shedding and no side effects. They experienced a severe initial shed but now have visual improvement, despite hair still being thinner than before.

Significant hair improvement was reported after 18 months of using 1mg dutasteride and 2.5-5mg oral minoxidil daily for diffuse unpatterned alopecia. The discussion includes praise, skepticism about authenticity, and concerns about side effects.

Hair loss discussion involves minoxidil, finasteride, and RU58841. Minoxidil non-responders may see results after adding stemoxydine due to increased enzyme presence.

PP405, developed by Pelage Pharmaceuticals, can reactivate dormant hair follicle stem cells and increase hair growth by 20% in eight weeks, unlike minoxidil or finasteride. However, skepticism remains about its effectiveness and availability, with concerns about funding and the timeline for broader access.

The user experienced significant hair regrowth using 0.5mg dutasteride and 5mg oral minoxidil, with fewer side effects compared to finasteride. They noticed improvements in hair thickness and hairline, despite intermittent use of performance-enhancing substances.

The user saw no significant changes in hair loss after three months on 3mg Dutasteride, having previously used Finasteride and 0.5mg Dutasteride. They plan to continue the high dose for a year despite concerns about side effects and diminishing returns.

Topical minoxidil can cause water retention, making the face appear swollen. Switching from liquid to foam and reducing application frequency may help; using dandelion root extract as a diuretic is also suggested.

A 30-year-old female with PCOS and male pattern baldness is frustrated with her endocrinologist's recommendation of only Spironolactone and minoxidil, feeling that dutasteride, finasteride, and progesterone would be more effective. Other users suggest various online sources for treatments, warn against self-medicating due to potential risks, and recommend seeking a specialized endocrinologist or considering additional treatments like Inositol, Berberine, and dermaneedling.

A user shared their year-long hair loss treatment using minoxidil, microneedling, and scalp massages, reporting moderate hair growth and stabilization. They suggest starting early with less harmful methods and consider adding finasteride or dutasteride if needed.