The user is experiencing hair regrowth in small clusters using oral minoxidil, oral finasteride, a red light cap, and Nizoral 2% shampoo. They are hopeful for continued improvement and thicker hair.
Human pluripotent stem cells have been used to create hair and skin, potentially offering a new solution for baldness. A user also mentioned starting finasteride but experiencing unexpected hair thinning.
The conversation discusses the importance of scalp skin barrier health in hairfollicle cycling, suggesting treatments like ceramides or niacinamide to support hair growth. It also mentions the use of finasteride for hair loss.
The conversation is about whether treatments like finasteride, dutasteride, and minoxidil can make single hairfollicles produce multiple hairs again. The user is curious if these medications can thicken hair and prolong the growth phase.
Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.
The conversation discusses potential future hair loss treatments, including SCUBE3, hairfollicle cloning, and GT20029, with mentions of past disappointments like CosmeRNA and hopes for treatments like Verteporfin for infinite donor hair.
The user is experiencing new hair growth after using oral dutasteride, topical minoxidil, and microneedling, but is concerned about black dots on the hairline, which might be clogged pores or dormant follicles. The user previously used a topical minoxidil/finasteride spray and had good results, despite a shedding phase after switching treatments.
Three months into using Minoxidil, finasteride, dermarolling, tretinoin, and saw palmetto shampoo, the user is seeing baby hairs on their hairline and is hopeful they will thicken. Another user reports that their own baby hairs have been getting thicker and longer over time.
PP405, a topical treatment, shows promise for hair growth by activating inactive follicles, with 66% of participants experiencing positive results. The treatment is well-tolerated and may proceed directly to Phase 3 trials, offering a potential alternative to minoxidil and finasteride.
PP405, developed by Pelage Pharmaceuticals, can reactivate dormant hairfollicle stem cells and increase hair growth by 20% in eight weeks, unlike minoxidil or finasteride. However, skepticism remains about its effectiveness and availability, with concerns about funding and the timeline for broader access.
A gel of keratin microspheres promotes hairfollicle growth, showing similar effectiveness to minoxidil in mice. The treatment activates hair growth pathways and reduces inflammation, with potential applications in drug delivery for hair-related disorders.
A 33-year-old man using finasteride, minoxidil, thickening shampoo, conditioner, and Nizoral noticed peach fuzz after a month and is hopeful for regrowth. Others shared mixed experiences, with some seeing further growth and others not.
A potential non-invasive topical treatment targeting the WNT Signaling Pathway for hair regeneration is being researched, with positive results on human hairfollicle cells. Current effective treatments for hair loss include Minoxidil, finasteride, and hair transplantation.
A new technique developed by scientists in Japan to reverse balding using hairfollicle cell transplants, and the discussion around the effectiveness of this approach compared to other treatments such as Minoxidil, finasteride, RU58841, Replicel, and Hairclone.
Minoxidil was applied to a single miniaturized hairfollicle over four months, resulting in less miniaturization but not yet terminal growth. The user used a 5% minoxidil solution, specifically the Regaine brand, and observed changes using a handheld WiFi microscope.
Stem cell-related treatments and drugs like RCGD423 and WAY are being tested for hair growth. Clinics are conducting tests on patients who haven't had previous treatments.
A user reported using oral Minoxidil 3mg, oral Finasteride 1mg, topical Minoxidil, dermarolling twice a week, and taking biotin and vitamin D daily for 10 weeks. They noticed small hairs growing at the hairline after 6 weeks.
Microneedling at depths greater than 0.6 mm may damage miniaturized hairfollicles, with 0.5 mm showing better results for hair regrowth. Combining microneedling with minoxidil enhances absorption, but caution is advised to avoid damaging follicles.
Hair loss impacts mental health, with treatments like Minoxidil, finasteride, and stem cell transplants discussed. There is hope for future breakthroughs, but current treatments are limited, and awareness is lacking.
PP405 is ineffective for miniaturized, fibrosed hairfollicles in androgenetic alopecia. AMP303 may activate hairfollicle stem cells, but minoxidil and finasteride are still the main treatments.
Hair cloning and injection of dermal papilla cells are discussed, with skepticism about their availability by 2023. Users mention Minoxidil, finasteride, and hair transplants as current treatments.
A user shared their experience with a hair restoration method involving adding individual human hairs on ultra-fine strands between existing hair, allowing for natural movement and appearance without blocking the scalp. They also continue using rosemary oil and gentle massage for basic growth support.
Hair regrowth treatments, including stem cell injections, are discussed, with skepticism about their effectiveness compared to Minoxidil and finasteride. Derma stamping is mentioned as effective when used with Minoxidil, finasteride, and dutasteride.
Balding scalps have more androgen receptors, leading to increased TGF-beta, which causes blood vessel loss and hairfollicle miniaturization. Blocking androgen signaling and TGF-beta may help prevent hair loss.
The conversation is about someone using topical finasteride, minoxidil, tretinoin, and caffeine for hair regrowth, particularly near the temple area. They are asking if the new, smaller hairs will grow and thicken to match their existing hair.
The user has been using a combination of finasteride/dutasteride, minoxidil, tretinoin, and hydrocortisone with microneedling and ketoconazole shampoo for hair loss. They are asking if the baby hairs growing will turn into terminal hairs with continued treatment.
A 16-year-old started using topical finasteride, minoxidil, and dermapen for hair regrowth, along with natural DHT blockers. Advice given includes being patient and considering waiting until 18-21 to use finasteride.
Hairfollicle regenerative therapy is being developed, with clinical trials planned in Japan, potentially allowing for hair cloning and eliminating the need for treatments like finasteride. If successful, the treatment could be available in Japan by 2025, but widespread access and affordability may take longer.
A new "third cell" discovery in Japan could be key to fully regenerating hairfollicles, with human trials possibly starting in 2027-2028. AI is expected to accelerate medical discoveries, potentially leading to a hair loss cure within a few years.