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      community Realistic timeline for hair regeneration and follicle cloning?

      in Technology  6 upvotes 3 months ago
      Hair regeneration and follicle cloning are considered far from being feasible, with current treatments like finasteride, minoxidil, and hair transplants expected to remain dominant for the next 15-20 years. Some are hopeful that AI advancements might accelerate progress, but many remain skeptical about significant breakthroughs in the near future.

      community 2 year progress on Min + Fin; transplant possible?

      in Is this regrowth?  65 upvotes 3 months ago
      An 18-year-old has been using minoxidil and finasteride for hair loss since age 15, recently adding dutasteride and GHK-Cu, but sees no significant improvement and is considering a hair transplant. Concerns are raised about using hormone suppressors at a young age, with suggestions to explore other treatments like dermarolling, diet changes, and checking for deficiencies.

      community Why not just take the drugs before hair loss?

      in Chat  123 upvotes 3 months ago
      Finasteride and dutasteride are discussed as preventative treatments for hair loss, with some advocating for early use and others concerned about side effects, especially before full maturity. Many regret not starting these treatments earlier due to their effectiveness in preventing or slowing hair loss.

      community Clascoterone - what we have right now

      in Research/Science  23 upvotes 3 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community GT20029: How It Works for Hair Loss - Hair Loss “Cure”

      in Research/Science  33 upvotes 4 months ago
      GT20029 is a potential treatment for androgenetic alopecia, addressing the root cause by targeting androgen receptors, unlike Minoxidil or Finasteride. It is seen as a preventative measure rather than a regrowth agent, with hopes for market release soon.

      community He is claiming, he can treat alopecia

      in Chat  357 upvotes 5 months ago
      A user claims a product can treat alopecia, but others are skeptical, calling it a scam due to lack of evidence and transparency. The product is said to inhibit Type II 5-αr by 22.9%, but is considered weaker than existing DHT blockers.

      community Fluridil (Eucapil) seems like a great option?

      in Treatment  4 upvotes 6 months ago
      The user stopped using finasteride due to side effects and is considering Fluridil (Eucapil) as an alternative for hair loss treatment. They are exploring other options like RU58841 and are interested in the experiences of others with Fluridil, noting its good safety profile despite the cost.

      community What’s your views on clascoterone 5% topical solution by cosmo

      in Research/Science  24 upvotes 6 months ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community 24M. 5.5 years on minoxidil and almost 5 years on fin/dut

      in Progress Pictures  72 upvotes 6 months ago
      A 24-year-old male shared his 5.5-year progress using minoxidil and nearly 5 years on finasteride/dutasteride for hair loss, reporting no side effects and successful results. He uses 0.5 mg dutasteride daily, oral minoxidil 2.5 mg daily, and topical minoxidil daily, with costs around $4 monthly.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

      in Research/Science  89 upvotes 6 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Don’t do like me. Don’t take a long break from Fin and Min

      in Chat  124 upvotes 7 months ago
      Stopping finasteride and minoxidil can cause significant hair shedding, so they should be continued indefinitely. Concerns about finasteride affecting fertility or causing birth defects are mostly unfounded, but some stop for personal reasons.

      community Quote from Pelage (PP-405) Spokesperson...

      in Research/Science  122 upvotes 7 months ago
      Pelage is developing a topical hair follicle stem cell therapy, PP405, for non-scarring alopecias like androgenetic alopecia, with Phase III trials planned and a potential market launch by 2027. The treatment may not require continuous use after initial regrowth.

      community The pessimism about the Crisp Cas 9 is excessive

      in Chat  11 upvotes 8 months ago
      CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

      community I’m finally starting to see fin results!

      in Treatment  15 upvotes 8 months ago
      The user started using finasteride daily and ketoconazole occasionally, noticing reduced hair fall but no regrowth. Others shared mixed experiences with finasteride, some considering switching to dutasteride or adding minoxidil.

      community Unwanted hair growth from minoxidil

      in Progress Pictures  57 upvotes 8 months ago
      Unwanted hair growth from minoxidil use, with suggestions to reduce dosage or switch to finasteride. Users recommend hair removal methods like shaving, waxing, or electrolysis to manage excess facial hair.

      community Should I risk changing to Dutasteride?

      in Finasteride/Dutasteride  10 upvotes 8 months ago
      The user is considering switching from Finasteride to Dutasteride for better hair regrowth, despite concerns about potential shedding and side effects. Opinions vary, with some suggesting the switch for stronger results and others advising caution due to possible side effects and the importance of consulting a doctor.

      community 3 days after a hair transplant

      in Transplants  2113 upvotes 9 months ago
      A user humorously shared their appearance three days after a hair transplant, sparking jokes and memes about their head shape. They remained positive, acknowledging the swelling and hoping for improvement.

      community FYI you can't donate blood when on fin/dut

      in Finasteride/Dutasteride  267 upvotes 9 months ago
      People on finasteride or dutasteride cannot donate blood due to the risk of birth defects if the blood is given to a pregnant woman. It's advised to stop finasteride for a month and dutasteride for six months before donating.

      community What I hate about being told to shave my head

      in Chat  258 upvotes 10 months ago
      Hair loss challenges and identity issues, with opinions on using finasteride, minoxidil, and hair transplants versus accepting baldness. Some find shaving more work, while others stress personal choice and self-perception.