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      community I got my bloodwork done... What now?

      in Update  6 upvotes 5 months ago
      The user has been experiencing hair thinning despite taking finasteride and minoxidil for six months. Bloodwork suggests a vitamin D deficiency, and users recommend consulting a doctor and possibly supplementing vitamin D.

      community 3 months on dut every other day min 3 times a week

      in Is this regrowth?  28 upvotes 1 year ago
      The user experienced hair regrowth and healthier hair after switching from finasteride to dutasteride, using it every other day along with minoxidil three times a week. They reported initial shedding but no side effects, and others in the conversation shared similar experiences or considered switching treatments.

      community (MTF 35) 20 Months Feminizing HRT

      in Transgender  18 upvotes 3 months ago
      A 35-year-old transgender woman experienced hair regrowth with feminizing HRT, adding dutasteride and bicalutamide, and plans a hair transplant for further improvement. Estrogen also improved skin appearance, and the user advises against cisgender men using feminizing HRT for hair regrowth.

      community started RU58841 today and am panicing

      in Treatment  8 upvotes 2 years ago
      A user started using RU58841 for hair loss and experienced anxiety and physical discomfort. Other users suggested avoiding the treatment due to similar side effects and recommended alternative treatments like pyri.

      community 18M 8 months progress 40mg daily dut stack

      in Progress Pictures  112 upvotes 1 year ago
      An 18-year-old is using a high-dose hair loss treatment with 40mg daily dutasteride, finasteride, minoxidil, tretinoin, and topical bicalutamide. Despite health risk concerns, especially liver issues, they report hair regrowth progress and intend to continue the regimen.

      community 6 Months Oral Dut/Min Progress

      in Progress Pictures  80 upvotes 7 months ago
      A 23-year-old male experienced significant hair regrowth and increased libido after switching from oral finasteride to 0.5 mg oral dutasteride and 2.5 mg oral minoxidil, following hair loss induced by a testosterone cycle. He reported initial shedding and decreased libido with finasteride, but no side effects with dutasteride, and noted improvements in hair density, temple regrowth, and reduced acne.

      community The mechanism of androgenic alopecia

      in Research/Science  34 upvotes 8 months ago
      DHT may inhibit hair growth by affecting mitochondrial function, leading to hair follicle miniaturization. Treatments like minoxidil and PP405 may promote hair growth by altering metabolic pathways, potentially counteracting DHT's effects.

      community 8 months Oral min and Dutasteride

      in Progress Pictures  62 upvotes 1 year ago
      Oral minoxidil and dutasteride are used for hair loss with mixed results. Some users report new growth, while others suggest scalp inflammation may be an issue.

      community RU58841 5% is roughly equivalent to Dutasteride 2mg — here's why

      in Research/Science  40 upvotes 3 months ago
      RU58841 5% is theoretically equivalent to 2mg of dutasteride for hair loss treatment, with RU58841 offering higher potential but more variability due to absorption issues. Users discuss the effectiveness of RU58841 and dutasteride, with some preferring dutasteride for consistent results and others finding success with RU58841.

      community 6 months dut, 5 months Minoxidil

      in Progress Pictures  42 upvotes 1 year ago
      The conversation is about a user's hair transformation after 6 months on Dutasteride and 5 months on Minoxidil, with the user noting significant improvement in their crown and hairline. The user switched from Finasteride to Dutasteride and uses oral Dutasteride daily and topical Minoxidil on the hairline and crown.

      community DLQ01: A Better "Minoxidil" PGF2a synthetic analogue.

      in Research/Science  3 upvotes 1 year ago
      DLQ01, a prostaglandin F2α analog, shows promise for hair growth by directly stimulating PGE2/PGF receptors without needing conversion, and can be combined with minoxidil and retinoids like tretinoin for enhanced effectiveness. Minoxidil's efficacy may be reduced by COX-1 inhibitors, but using prostaglandin analogs like Latanoprost or Bimatoprost can help maintain its effectiveness.

      community My Progress. July 21st 2025 x April 22nd 2026

      in Progress Pictures  811 upvotes 1 month ago
      A user shared their hair regrowth progress using oral Dutasteride, Biotin, and Minoxidil over nine months, reporting significant improvement without surgery. They emphasized the effectiveness of these medications and noted no side effects.

      community 9 Month Journey: Massive Second Minoxidil Shed?

      in Minoxidil  43 upvotes 1 year ago
      A 33-year-old man shared his 9-month journey using minoxidil for hair loss, experiencing significant shedding after initial success. He is considering adding finasteride but is hesitant due to trying to conceive.

      community 2,5-3 months progress. I might be a hyper responder?

      in Is this regrowth?  17 upvotes 2 months ago
      The user is experiencing reduced hair shedding and increased hair density after using finasteride, minoxidil, derma rolling, granactive retinoid, and Nizoral, while also taking testosterone and aromatase inhibitors. They question if they are a hyper responder to the treatments, despite mixed feedback from others about visible progress.

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  13 upvotes 2 years ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community 10 month update transplant 2300 grafts & 7 1/2 months min/fin topical

      in Progress Pictures  30 upvotes 2 years ago
      A user shared a 10-month update on their hair loss treatment, including a hair transplant of 2300 grafts and 7.5 months of using a topical minoxidil/finasteride solution and ketoconazole shampoo. They expressed regret for not starting the medications sooner and reported side effects like heart palpitations, which improved after cutting out caffeine.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

      in Research/Science  215 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community 50% test increase after 18 months of taking DUT

      in Update  57 upvotes 1 year ago
      A user reported a 50% increase in testosterone after 18 months of taking dutasteride for hair loss. The conversation includes skepticism about the reliability of single testosterone tests and questions about estrogen levels.

      community Fluridil degrades the androgen receptor.

      in Research/Science  12 upvotes 1 year ago
      Fluridil degrades androgen receptors, which are prevalent in the scalp and other tissues. People with androgenetic alopecia (AGA) may have higher expression of these receptors and 5AR activity in affected scalp areas.

      community 1.5 yrs on min+ fin. Dut switch?

      in Is this regrowth?  24 upvotes 2 months ago
      The user has been using oral finasteride and minoxidil for 1.5 years with some crown improvement but still experiences thin hair and a receding hairline. They are considering switching to dutasteride for potentially better results, while others suggest adding topical minoxidil back into the routine.