Search
for

    Sort by

    Community Join

    180-210 / 1000+ results

      community I cry every day, everything is very depressing

      in Finasteride/Dutasteride  52 upvotes 1 year ago
      A user is experiencing hair loss despite using dutasteride and oral minoxidil, feeling hopeless and considering a hair system. They are advised to try ketoconazole, seek a second opinion from a dermatologist, and consider treatments like finasteride, RU58841, and hair transplants.

      community An *insane* RU58841 success story

      in Progress Pictures  95 upvotes 1 year ago
      RU58841, oral and topical minoxidil, finasteride, and ketoconazole shampoo led to significant hair regrowth, though some suspect a hair transplant. Concerns about RU58841's side effects, like anxiety and heart issues, were discussed.

      community What else is good. Besides the big 3.

      in Chat  35 upvotes 1 year ago
      Key treatments for hair preservation include minoxidil, finasteride/dutasteride, and microneedling, with additional options like specific shampoos, oils, biotin, zinc, tretinoin, clascoterone, and low-level laser therapy. Maintaining a healthy lifestyle, reducing stress, and addressing nutrient deficiencies can also support hair health.

      community 3 month progress! (Min and derma only)

      in Is this regrowth?  239 upvotes 1 year ago
      The user reported hair regrowth progress using minoxidil and dermapen, considering adding finasteride. Others shared experiences with minoxidil, finasteride, and microneedling, recommending finasteride for long-term results but noting potential side effects.

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI

      in Finasteride/Dutasteride  26 upvotes 1 year ago
      The conversation discusses the effectiveness and skepticism around topical dutasteride for hair loss, with mentions of combining it with other treatments like minoxidil and oral medications. Some users doubt its efficacy due to lack of independent studies and potential conflicts of interest.
      The story of RU58841/ PSK3841

      community The story of RU58841/ PSK3841

      in Research  622 upvotes 1 year ago
      RU58841, a potential hair loss treatment, was not commercialized due to marketability issues and lack of long-term safety data. Concerns about its formulation and delivery methods further complicate its use.

      community Shedding again after 6 months of great results.

      in Minoxidil  15 upvotes 1 year ago
      A user experienced shedding after 7 months on Fin/Min spray despite good results and no change in treatment. Other users noted similar experiences and mentioned that shedding periods can be normal.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  362 upvotes 2 years ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Diffuse thinning is the worst man

      in Chat  248 upvotes 2 years ago
      The conversation is about the struggles of dealing with diffuse thinning at a young age and the lack of significant improvement after using treatments like finasteride and minoxidil. Some suggest additional methods like derma rolling, microneedling, and hair fibers, while others share their own experiences and encourage persistence with treatment.

      community Big sheeding after 9 months on minoxidil. Maybe caused by switching brands?

      in Minoxidil  133 upvotes 2 years ago
      A user experienced significant hair regrowth using Minoxidil but started shedding hair after switching brands and adding treatments like Topical Finasteride and microneedling. They also faced increased hair loss after using Ketoconazole shampoo and are seeking advice on whether brand switching or the shampoo could be the cause.

      community How to BECOME a RESPONDER to Fin/Dut if you are not responding

      in Finasteride/Dutasteride  311 upvotes 2 years ago
      The conclusion of this conversation is that the user "DuckSeasonCamelSeasn" found that consuming grapefruit juice prior to taking finasteride or dutasteride helped them become a responder to the medications and regain hair growth. However, there are warnings about potential risks and interactions with other medications, so caution should be exercised.

      community What ever happened to pyrilutamide?

      in Technology  48 upvotes 3 years ago
      Pyrilutamide, a potentially effective hair loss treatment; other topical treatments like RU58841 and CB-03-01 that may have fewer side effects than Pyrilutamide; and the Phase 3 clinical trials of Pyrilutamide, which is likely to be approved by the FDA soon.

      community Today I didn’t go to my cousin marriage because of my hair. I feel really depressed, I just want to disaper, i can’t take this anymore. I tried everything for the past 3 years, and I’m just 21 years. I’m isolating myself from othesrs.

      in Finasteride/Dutasteride  284 upvotes 3 years ago
      A 21 year-old feeling depressed about hair loss and how to cope with it, discussing various treatments such as finasteride, minoxidil, dutasteride, hair pieces, and scalp micropigmentation. There is also discussion of accepting oneself and redefining self-worth in order to not base one's entire identity on their hair.

      community It’s over. NOTHING has worked.

      in Chat  95 upvotes 3 years ago
      A user who has been trying various treatments for hair loss for four years, with no success. Suggestions include use of minoxidil, finasteride, RU58841, microneedling, supplements and multivitamins, lifestyle changes, scalp biopsy, and SMP.

      community Tressless Pyrilutamide data analytics – Frustrated with lack of data, so I did something about it!

      in Treatment 3 years ago
      This user has conducted data scraping of 365 Reddit posts on the hairloss drug Pyrilutamide over the last year to analyse efficacy and side effects. The findings, which are available in a 19 page report with graphs, suggest that 22% of Pyrilutamide users experience positive results while 63% experience symptoms. A larger analytics project is proposed for other drugs with enough demand.

      community 1 year on fin. No results. I give up.

      in Finasteride/Dutasteride  43 upvotes 3 years ago
      A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.

      community Is Pyrilutamide the real deal and if so when will it actually be available?

      in Chat  21 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that is currently in development and may be available soon; an androgen receptor degrader which is also being developed as a potential treatment for hair loss; and the comparison between Pyrilutamide, finasteride, minoxidil, and RU58841.

      community Kintor Phase 2 Results released KX-826 (pyrilutamide)

      in Research/Science  444 upvotes 3 years ago
      Kintor Pharmaceutical's Phase 2 results with the drug Pyrilutamide, a potential alternative to 5-ARI drugs like Finasteride and Dutasteride but without the side effects. It could be used in combination with other topical treatments such as Minoxidil. The safety of the drug has been demonstrated in 6 months of use, however there are still questions about long term efficacy and systemic absorption.

      community Binding affinity of pyrilutamide!

      in Update  168 upvotes 4 years ago
      Pyrilutamide, a nonsteroidal antiandrogen drug under development for the potential treatment of androgenic alopecia. The conversation discusses its binding affinity to the androgen receptor and the timeline for possible availability after trials are completed in the United States and China.