Adding creatine while using finasteride and minoxidil caused skin irritation and hair thinning. Creatine may affect DHT levels, leading to these issues.
Minoxidil and finasteride work through different mechanisms; minoxidil-dependent hair requires continued use to maintain growth, while finasteride prevents further hair loss but cannot sustain minoxidil gains alone. Current treatments like minoxidil, finasteride, and others need indefinite use, as no permanent solution exists yet.
Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.
Hair growth success may be linked to addressing scalp fungi issues, with treatments like minoxidil, finasteride, and dutasteride being important. DHT may contribute to scalp microbial issues, potentially causing inflammation and hair loss.
A 24-year-old male experienced side effects like low libido and ED after starting finasteride post-hair transplant and is seeking alternatives to reduce scalp DHT. Suggestions include topical finasteride, Xpecia, DHT-reducing shampoos, and switching to dutasteride, with some users reporting fewer side effects with these alternatives.
Long aerobic exercise (over 60 minutes) can reduce DHT levels and improve hair health. Some users discuss using Tadalafil (Cialis) to further reduce DHT after exercise, while others mention using treatments like Minoxidil, Finasteride, and RU58841 for hair growth.
A 38-year-old man reports positive results using topical Minoxidil 5% and infrared therapy for hair regrowth over four months, along with Saw Palmetto and Pumpkin Seed Oil supplements. Others suggest adding Finasteride for better maintenance and discuss the role of DHT blockers.
Rob English's scalp massages are discussed as a method to reduce DHT and stop hair loss, but many users criticize it as ineffective compared to treatments like finasteride, dutasteride, and minoxidil. Some users argue that alternative treatments like scalp massages and microneedling can work for some, but the community largely favors the "big three" medications.
A user reported hairline regrowth after two weeks on a treatment including finasteride, peppermint and rosemary oils, emu oil, magnesium oil spray, apple cider vinegar, and dermarolling, while avoiding shampoos and conditioners. They believe DHT contributes to hair loss but also suggest follicle fibrosis is an issue.
A 55-year-old man shared his successful hair transplant results, using 9,100 grafts from his scalp and beard, and is also using minoxidil, finasteride, and multivitamins. The discussion includes opinions on the necessity of DHT blockers and the effectiveness of the transplant, with some users questioning the need for such procedures at an older age.
Minoxidil can stimulate hair growth but does not prevent long-term hair loss, while finasteride or dutasteride is necessary to address DHT and maintain hair. Family hair history may not predict individual outcomes, and combining treatments like microneedling can enhance results.
Using a combination of low-dose oral and topical finasteride, along with minoxidil, may effectively manage hair loss by targeting both systemic and local DHT. Users report positive experiences with this regimen, noting good tolerability and no worsening of hair condition.
Hair loss can be caused by various factors such as stress, thyroid issues, and genetics. Treatments mentioned include dutasteride, DHT blockers, and thyroid medication, though results vary.
Creatine is debated for causing hair loss, with some users claiming it raises DHT levels, while others argue it has no significant effect. Despite conflicting opinions, some users report hair loss even when using DHT blockers like finasteride.
A user claims a product can treat alopecia, but others are skeptical, calling it a scam due to lack of evidence and transparency. The product is said to inhibit Type II 5-αr by 22.9%, but is considered weaker than existing DHT blockers.
A 25-year-old woman using minoxidil 2% for hair loss is experiencing faster hair growth and new baby hairs but continues to lose hair and see miniaturization. Suggestions include switching to minoxidil 5%, checking vitamin levels, using Nizoral, and considering a DHT blocker.
A user with thinning, curly, dry hair is seeking affordable shampoo and conditioner recommendations. They are using oral minoxidil and apply argan oil, but dislike products with keratin and biotin, and another user suggests ketoconazole shampoo for added density and DHT blocking.
A 27-year-old at Norwood 3 is starting a hair loss treatment journey using finasteride, dutasteride, minoxidil, biotin, scalp massages, and ketoconazole shampoo. The focus is on reducing DHT and stimulating growth, with finasteride emphasized as the key long-term solution.
Shampoos are generally ineffective for stopping hair loss or blocking DHT, with treatments like minoxidil and finasteride being more effective. Finasteride can stop hair loss in some cases, but often only slows it down for most users.
A user discusses their hair loss and current natural treatments, including derma stamp, rosemary oil, wild growth hair oil, biotin, omega 3, and a small DHT blocker. Another user suggests the hair loss is androgenic alopecia and recommends either taking finasteride or accepting the hair loss.
A user shared that after quitting caffeine and restarting oral minoxidil, they experienced significant hair regrowth, suggesting that caffeine might interfere with minoxidil's effectiveness by blocking adenosine receptors. They also mentioned side effects like water retention and dizziness, which subsided after a few weeks, and are not using any DHT blockers.
Using oral finasteride in combination with topical minoxidil and dermarolling for hair loss. Some users have reported significant regrowth when adding finasteride to their minoxidil routine, suggesting that reducing DHT levels may be a key factor in hair regrowth.
Minoxidil may suppress androgen activity in hair follicles, potentially aiding in hair growth and prostate cancer treatment. Users discuss the effectiveness of minoxidil and finasteride for hair maintenance and regrowth, with some preferring topical applications over oral due to safety concerns.
A 32-year-old female seeks ways to lower DHT without weight gain, experiencing issues with spiro and saw palmetto. Suggestions include topical finasteride, low-dose oral therapies, and checking various health markers.
An 18-year-old has been using 5% topical minoxidil for 2 months for hair loss, with a history of vitamin D deficiency and thyroid imbalance. Users suggest starting finasteride and blocking DHT for androgenetic alopecia (AGA).
KX-826 Phase II results show that a 0.5% concentration performs better than 1% for treating male pattern baldness. Concerns about receptor upregulation from long-term DHT antagonism were mentioned.
A user is seeking advice on adding dutasteride to their finasteride regimen to stop DHT-related scalp itch. They have tried selenium sulfide and ketoconazole shampoos with temporary success.
Oral minoxidil has shown positive results for hair regrowth, but concerns about its side effects, such as heart issues, are noted. Adding a DHT blocker like finasteride is recommended for better and more lasting results.
A study that outlines the full model for androgenic alopecia (AGA) which links DHTto cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.