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      community Hair is kinking rapidly following hair loss

      in Update  1 upvotes 11 months ago
      Hair loss has slowed, but uneven growth and kinking persist despite using keto/nizoral shampoo and clotrimazole. Stress and anxiety might be contributing factors.

      community [21M] seb derm + probably mbp.

      in Research/Science  4 upvotes 3 years ago
      Minoxidil and finasteride are being considered for hair loss due to seborrheic dermatitis and male pattern baldness. The user is also using ketoconazole and zinc pyrithione shampoo.
      16 advice on routine I’m beginning

      community 16 advice on routine I’m beginning

      in General  126 upvotes 1 year ago
      The user is experiencing hair thinning and bald spots, using Nizoral, rosemary oil, fluocinolone, and receiving PRP treatments. They are considering oral minoxidil and finasteride but are hesitant due to age and financial constraints.

      community Pelage are starting phase 3 for PP405 towards the end of 2026

      in Chat  180 upvotes 4 months ago
      PP405 is moving to late-stage trials, showing potential for hair regrowth, with 31% of male patients experiencing a 20% increase in hair density. Veradermics is developing an oral minoxidil version, and there is interest in combining treatments for better results.

      community My experience with Pyrilutamide

      in Update  3 upvotes 2 years ago
      The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.

      community How do you prevent infection with derma needling / derma stamping?

      in Microneedling  1 upvotes 1 year ago
      The conversation discusses preventing infection from derma stamping for hair loss treatment, with suggestions to reduce needle depth and consider alternatives like tretinoin. The user experienced irritation possibly from zinc chloride and stopped using the shampoo and derma stamping.

      community Facial hair loss

      in Treatment 5 years ago
      User noticed beard and sideburn hair loss, and thinning eyebrows, diagnosed with alopecia barbae and male pattern baldness, and prescribed Desonide cream. User seeks feedback on Desonide cream.

      community I have this tingling sensation on my scalp (mainly crown)

      in Chat  7 upvotes 10 months ago
      The conversation is about a user experiencing a tingling sensation and redness on their scalp, possibly related to hair loss treatments. Suggestions include using Nizoral shampoo and consulting a dermatologist, while the user mentions using oral finasteride.

      community any news about DUPA (Diffuse unpatterned alopecia)?

      in Research/Science  8 upvotes 3 years ago
      The conversation discusses diffuse unpatterned alopecia (DUPA) and its possible causes, including sensitivity to DHT, not being androgenic alopecia, being diffuse alopecia areata, or hormonal issues. Treatments mentioned include topical melatonin, Clobetasol Propionate for alopecia areata, and the lack of results from using finasteride, dutasteride, and minoxidil.

      community Still thinning on dut + oral min

      in Treatment  12 upvotes 5 months ago
      A 26-year-old is experiencing worsening hair thinning despite using dutasteride 0.5 mg and oral minoxidil 5 mg, alongside ketoconazole for seborrheic dermatitis. Users suggest patience, as results may take 12–18 months, and consider increasing the dutasteride dosage or consulting a dermatologist.

      community Vitamin D deficiency - could it be the cause?

      in Update  6 upvotes 1 year ago
      The user is experiencing hair thinning and has a vitamin D deficiency, which they suspect might be causing the issue, but they are also considering androgenic alopecia (AGA) as a cause. They are currently using minoxidil and are unable to get finasteride prescribed, while others suggest addressing the vitamin D deficiency and consulting a dermatologist.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

      in Research/Science  58 upvotes 2 months ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community RU58841 vehicle penetration (Study for minoxidil)

      in Treatment  12 upvotes 3 years ago
      The user mixes their own RU58841 solution and found that increasing the ethanol content improved absorption and reduced scalp itching. A study on minoxidil showed that penetration increased with higher ethanol concentrations, reaching maximum penetration at 90% ethanol.

      community Anyone in Pyrilutamide currently?

      in Treatment  13 upvotes 3 years ago
      User considers trying Pyrilutamide for hair loss and itch relief. Another user shares positive experience with Pyrilutamide, no side effects.

      community Cetirizine (Zyrtec), to help with inflammation.

      in Product  3 upvotes 1 year ago
      The user experiences an itchy scalp and finds relief using shampoo and Zyrtec, which helps with inflammation. They are unsure if the issue is related to histamines or seborrheic dermatitis.

      community PTD-DBM Update: Q&A With Dr. Kang-Yell Choi

      in Treatment  13 upvotes 6 years ago
      PTD-DBM is being explored for hair regrowth by targeting CXXC5, with clinical trials expected after pre-clinical studies. Users express anticipation and skepticism about its effectiveness.

      community Not happy with current routine, suggestions for improvement?

      in Treatment  1 upvotes 4 years ago
      A 26-year-old male is unhappy with his current hair loss routine, which includes microneedling, ketoconazole shampoo, and a topical formula with Minoxidil, Finasteride, and other ingredients. He struggles with consistency due to ADHD and is considering switching to oral medication for simplicity, but is concerned about side effects and effectiveness.

      community DHEA, the culprit behind DUPA ? Read this!

      in Research/Science  19 upvotes 2 years ago
      High DHEA levels may contribute to hair loss by increasing DHT in hair follicles, potentially explaining why finasteride is ineffective for some. Treatments like high-dose dutasteride and RU58841 are suggested, but the underlying cause, such as adrenal issues, should be investigated.

      community Pyrilutamide 5 months results (before, after pics)

      in Progress Pictures  195 upvotes 3 years ago
      Tae147 has shared results of using pyrilutamide, a 5% concentration topical solution applied twice daily, in combination with minoxidil, to reduce scalp itchiness and hair shedding. Other users have shared their experiences with the treatment, as well as questions about its availability on the market.

      community Sugar and Hair loss connections

      in Research/Science  41 upvotes 1 year ago
      High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgen levels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.

      community One+ year 1mg Fin, Ketoconazole, and 3.75 Oral Min. I have DUPA. Switched from Topical to Oral Min.

      in Progress Pictures  142 upvotes 3 years ago
      A user's experience with hair loss treatments such as finasteride, ketoconazole, and oral minoxidil that have not yielded any results; other users suggest shaving the head or getting a wig, while others offer additional advice such as seeing a dermatologist, checking thyroid levels, switching to dutasteride and adding needling, and trying stemoxydine.

      community Why is no one pointing out dandruff as the number 1 evidence/symptom of MPB?

      in Chat  55 upvotes 2 years ago
      The post discusses the theory that persistent dandruff in areas prone to hair loss could be a sign of hair follicles dying due to DHT, indicating balding. The responses vary, with some users noting improvements in dandruff and hair loss with treatments like Dutasteride, while others experienced hair loss without dandruff.