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      community What hormones/vitamins should I test for?

      in General  51 upvotes 1 year ago
      The user plans to test for DHT, total testosterone, free testosterone, E2, SHBG, and prolactin while supplementing with vitamin D and monitoring ferritin levels. They are experiencing hairline thinning and are seeking advice on whether their approach is excessive or lacking.

      community Anagen is now selling pyrilutamide

      in Product  138 upvotes 3 years ago
      Pyrilutamide, a potential hair loss treatment that has recently been released for sale, and is thought to have similar efficacy to Dutasteride without side effects. It was discussed in terms of its effectiveness compared to Finasteride, its use by females, and whether it can be safely mixed with RU58841.

      community Hair follicle neogenesis

       7 upvotes 11 years ago
      A user plans to experiment with creating new hair follicles using methods like derma rolling, applying lithium chloride, tannic acid, and various other substances including caffeine, ketoconazole, and raspberry ketones. They also consider using anti-inflammatories, immunosuppressants, and DHT inhibitors to potentially improve results.

      community Is stemoxydine (serioxyl advanced) toxic/lethal to cats?

      in Chat  1 upvotes 1 year ago
      The conversation is about concerns regarding the safety of using stemoxydine (Serioxyl Advanced) around cats, with the user also using minoxidil, oral minoxidil, dutasteride, and microneedling for hair loss. The user is seeking advice on whether stemoxydine is toxic or lethal to cats.

      community What’s your views on clascoterone 5% topical solution by cosmo

      in Research/Science  24 upvotes 6 months ago
      Clascoterone 5% topical solution shows promise for treating male-pattern hair loss by blocking DHT at the follicle without systemic absorption, potentially offering fewer side effects than oral treatments like finasteride. While results are promising, long-term safety and effectiveness need further study, and it may serve as a starting point for developing more effective treatments.

      community What's the deal with Spectral.DNC-N/'nanoxidil'?

      in Minoxidil  5 upvotes 3 years ago
      Nanoxidil is considered to have better absorption and fewer side effects than minoxidil, with added DHT blockers. The user is questioning if switching to the more expensive Spectral.DNC-N is worthwhile compared to cheaper options like Kirkland minoxidil.

      community Your opinion on those compounds ?

      in Product 1 year ago
      Minoxidil, finasteride, and dutasteride are effective for hair loss. Alternative treatments like oils and supplements are less effective and more costly.

      community Black market pp405? Title title

      in Treatment  8 upvotes 5 months ago
      PP405 is likely fake, and JXL069 is an unrefined prototype with unknown side effects. It's advised to wait for the official PP405 release.

      community Hair loss - Blood work (High DHEAS)

      in Research/Science  9 upvotes 4 years ago
      A user has been taking finasteride for 5 months with no improvement in diffuse hair loss and suspects high levels of prolactin, cortisol, progesterone, and DHEAS, as well as iron, might be contributing to the issue. They are also taking vitamin D to address a deficiency.

      community Does anyone homebrew their own minox/ru58841

      in Chat  1 upvotes 2 years ago
      A bodybuilder discusses homebrewing Minoxidil and RU58841 using propylene glycol or MCT. They inquire about the feasibility and potential risks of these methods.

      community European release of clascoterone

      in Research/Science  13 upvotes 2 months ago
      Clascoterone's European release is expected in Q4 2026, with FDA approval anticipated by mid-2027. The discussion includes questions about the approval timeline and potential acceleration due to unmet needs.

      community Studies show: 0.2 mg reduces scalp DHT by ~55%. 1 mg reduces it by ~64%. 5 mg reduces it by ~69%.

      in Finasteride/Dutasteride  148 upvotes 8 months ago
      Finasteride reduces scalp DHT significantly even at low doses, with 0.2 mg reducing it by about 55%, but higher doses like 1 mg and 5 mg offer only marginally more reduction. Users discuss side effects, with some experiencing none and others reporting issues like low libido, and they also mention using other treatments like minoxidil and dutasteride.

      community Recommend stemoxydine as an adjunct therapy

      in Treatment  4 upvotes 2 years ago
      The user has been using finasteride, minoxidil, retinoid, and occasional microneedling for hair loss with good results. They recently added stemoxydine, which improved their hair further, and suggest trying it, especially in the EU where it's easily available.

      community Stacking Fluridil / Topilutamide with other + aqueous topicals?

      in Technology  1 upvotes 2 years ago
      The conversation discusses how to use fluridil/topilutamide with other hair loss treatments like liquid minoxidil and CB-03-01, considering fluridil's hydrophobic nature and potential degradation with water. The user questions the necessity of washing hair only once per week as suggested by the manufacturer.

      community Finally got hold of 0.1% latanoprost

      in Treatment  7 upvotes 3 months ago
      The conversation is about a user obtaining a compounded treatment for hair loss, including 0.1% latanoprost, 0.2% melatonin, and 1% cetirizine. The user also uses 2.5 mg dutasteride, 5 mg minoxidil, and RU58841 daily, and is at Norwood 2.

      community Sharing what worked for me (PCOS related hair loss)

      in Female  35 upvotes 2 years ago
      A user with PCOS experienced hair loss and found success using a triple dose of O.N.E Omega by Pure Encapsulations after discovering low Omega fatty acids. Biotin provided minimal improvement, but the Omega supplement significantly restored hair.

      community No access to RU, Pyri. Any alternative anti androgen?

      in Treatment  4 upvotes 1 year ago
      The conversation discusses alternatives to RU58841 for hair loss treatment, with suggestions including topical spironolactone, peppermint and rosemary oils, and saw palmetto. The user also considers ordering RU58841 from China but finds it too expensive.

      community Topical Dutasteride Options

      in Finasteride/Dutasteride  8 upvotes 5 years ago
      The user is using a topical dutasteride/minoxidil/tretinoin gel for hair thinning and has had a positive experience with no side effects. They also mention considering another product, Formula82D, after having decent results with Formula82F.

      community The future of hair loss drugs.

      in Research/Science  31 upvotes 4 months ago
      Clascoterone 5% and PP405 are being discussed as potential future treatments for hair loss, with clascoterone nearing phase three completion and PP405 possibly taking a cosmetic route to market. Current treatments like minoxidil, finasteride, and RU58841 are mentioned as effective in slowing hair loss, but a complete cure remains elusive.

      community Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia.

      in Research/Science  13 upvotes 2 years ago
      A quercetin-encapsulated and polydopamine-integrated nanosystem (PDA@QLipo) shows promise for treating androgenetic alopecia by reshaping the perifollicular microenvironment, outperforming minoxidil in hair regeneration. The nanosystem promotes cell proliferation, hair follicle renewal, and recovery by scavenging reactive oxygen species and enhancing neovascularity.

      community How I stopped minoxidil build up on my scalp.

      in Minoxidil  49 upvotes 1 year ago
      Switching from minoxidil with propylene glycol to a glycerin-based solution helped reduce scalp buildup and dandruff. Using ketoconazole shampoo and a scalp massager also improved scalp health.

      community Boys I am just a gonner. What on earth is my scalp even going through. Looks like world war 3. Pyril 3 months. Topical melitonin/progesterone/fin, dut, fin, oral min, laser trash, anus stimulation. Nothing. Donor area is decimated 😂.

      in Progress Pictures  83 upvotes 3 years ago
      Treating Seborrheic Dermatitis, a fungal scalp condition which can cause hair loss. Treatments discussed include antifungal shampoos, cold showers, exfoliating the scalp, taking Vitamin D, and stimulating the prostate through the anus.

      community 5% capixyl 3%redensyl+procapil

      in Product  5 upvotes 2 years ago
      The conversation is about a hair loss serum mix containing 5% capixyl, 3% redensyl, and procapil. The user is asking for recommendations or opinions on the effectiveness of this product.