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      community Topical Dutasteride usage plan + build up prevention

      in Finasteride/Dutasteride  8 upvotes 4 months ago
      The conversation discusses using a 0.03% topical Dutasteride solution for hair loss, as it may be more effective than Finasteride with fewer systemic side effects. OP plans to apply it daily for 100 days, then reduce frequency, due to past negative cognitive effects from oral treatments.

      community Breezula 6 Month Topline Phase III Results Released

      in Research/Science  173 upvotes 4 months ago
      Breezula shows promising hair growth results, with up to 539% increase in hair count compared to placebo, and regulatory submissions are planned in the US and EU. Users are cautiously optimistic, noting the potential for Breezula to replace finasteride by targeting DHT without systemic effects.

      community 5months using Dut/Min twice daily

      in Is this regrowth?  69 upvotes 2 weeks ago
      A 33-year-old male has been using topical dutasteride and minoxidil twice daily, along with a 0.25 mm derma roller every five days, and is experiencing hair shedding but seeing progress. Some users suspect a hair transplant, while others praise the results.

      community Finasteride/ Dut dosage advice

      in Finasteride/Dutasteride  4 upvotes 2 years ago
      A 33-year-old user is seeking advice on adjusting their hair loss treatment, which includes daily finasteride, oral minoxidil, and various supplements. They are considering switching to alternate-day dosing of finasteride or dutasteride and are concerned about potential shedding and effectiveness.

      community 35 days on fin + minoxidil ...

      in Progress Pictures  138 upvotes 9 months ago
      The user reported significant hair density improvement after 35 days using finasteride (1.25 mg) and 5% minoxidil. Some users are skeptical, while others believe the progress is genuine.

      community Duasteride and breast tissue accumulation.

      in Finasteride/Dutasteride  1 upvotes 1 month ago
      The user is experiencing breast tissue growth from taking dutasteride and minoxidil, and is considering reducing the dosage or stopping the medication. Suggestions include seeing an endocrinologist, using Raloxifene or Arimidex, and considering topical treatments or surgery if necessary.

      community 30 M diffuse shining/bolding crown - stack

      in Treatment  2 upvotes 1 year ago
      A 30-year-old with diffuse thinning and a balding crown is using a treatment regimen of a 2-in-1 pill containing finasteride, minoxidil, and biotin, along with various supplements. After two weeks, no side effects have been experienced, and updates with pictures will be posted monthly.

      community Minoxidil and Finastride topical solution 2 months update

      in Minoxidil  6 upvotes 1 month ago
      A 34-year-old woman has been using a topical solution of 5% Minoxidil and 0.1% Finasteride since January 2026 to address hair thinning caused by PCOS and poor nutrition. She reports ongoing hair shedding but has improved her diet with whole foods and supplements.

      community Dutasteride mesotherapy to lower dut dose

      in Finasteride/Dutasteride  1 upvotes 7 months ago
      The conversation is about a user considering reducing their dutasteride dose due to side effects like lower libido and watery semen. They plan to use dutasteride mesotherapy every three months to maintain hair while reducing systemic DHT suppression.

      community We need more people trying 2.5 mg dutasteride

      in Finasteride/Dutasteride  7 upvotes 1 year ago
      Increasing the dutasteride dose to 2.5 mg may significantly reduce DHT and promote hair regrowth, with similar side effects to lower doses. Some users combine dutasteride with minoxidil and finasteride for better results, but there are concerns about long-term effectiveness and availability.

      community Finasteride 5mg for female pattern hair loss

      in Female  7 upvotes 5 years ago
      The user's experience of using Finasteride 5mg and Aldactone 50mg to treat Female Pattern Hair Loss, as well as their use of PRP injections for further hair growth.

      community Topical Finasteride: Update

      in Finasteride  66 upvotes 6 years ago
      A user applied a homemade topical finasteride solution daily for 35 days, reducing hair shedding significantly with minimal side effects. They plan to continue for 90 days and will provide further updates.

      community 28M 0.5MG DUT 5MG MIN - PROGRESS PIC & THANKS

      in Progress Pictures  76 upvotes 1 week ago
      A 28-year-old male shares progress on hair loss treatment using 0.5mg dutasteride and 5mg minoxidil, experiencing initial shedding but encouraged by community support. He also uses ketoconazole occasionally based on scalp oiliness.

      community Taken the plunge - thanks for all your support.

      in Minoxidil  1 upvotes 1 year ago
      A user, almost 50, has been using finasteride for 30 years and recently added oral dutasteride to address hair recession. They are now trying a new treatment stack including Minoxidil, Dutasteride, Melatonin, Rosemary oil, and Bimatoprost, along with derma stamping and Ketoconazole shampoo.

      community 16 days. Topical Min 5% once a day • derma roller 0.25mm every day, 1mm once a week • Foligain Trioxidil shampoo (I let it rest for 10 minutes) • mix of supplements

      in Progress Pictures  102 upvotes 11 months ago
      The conversation is about a user's hair regrowth progress using topical Minoxidil 5%, a derma roller, Foligain Trioxidil shampoo, and various supplements like zinc, selenium, magnesium, B6, B7, saw palmetto, and D3 + K2. The user is seeking finasteride but faces prescription challenges in Italy.

      community 33 M - one year on 0,5 tret + 5% min

      in Progress Pictures  31 upvotes 1 week ago
      A 33-year-old man used Minoxidil 5% and Tretinoin 0.05% for a year to address hair thinning and receding hairline, resulting in new "baby hairs" filling in thin spots. He applies Tretinoin first, lets it dry, then applies Minoxidil, and notes that consistent use is necessary to maintain results.

      community M25 Dutasteride is the best thing that ever happened to me

      in Update  90 upvotes 4 weeks ago
      A 25-year-old switched from finasteride to dutasteride, experiencing significant hair regrowth and improved hair quality after 6 months, taking it three times a week. The user stopped finasteride entirely, citing dutasteride's longer half-life as more effective.

      community Need supplemental products in addition to oral minoxidil and oral dutasteride

      in Product  1 upvotes 6 months ago
      The user has been using oral minoxidil and dutasteride for hair loss without success and is considering adding topical 17α-estradiol, Pyrilutamide, Clascoterone, or cetirizine. They have confirmed low serum DHT levels and are exploring additional treatments due to genetic sensitivity to DHT and prostaglandin D2.

      community 6 weeks 5mg min 0.5mg dut progress

      in Progress Pictures  7 upvotes 11 months ago
      A 35-year-old man shares his positive progress in hair regrowth using a daily routine of 5mg oral minoxidil and 0.5mg dutasteride, along with a low light cap, weekly dermarolling, and biweekly ketoconazole shampoo. He reports noticeable improvements without side effects and aims to inspire others considering similar treatments.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Dutasteride is amazing even for women with FAGA!

      in Female  151 upvotes 7 months ago
      Dutasteride significantly improved hair health and reduced shedding for a woman with PCOS and hyperandrogenism, without causing depression or anxiety, unlike finasteride. Dutasteride also helped with PMDD symptoms and had no side effects, though it changed hair texture.

      community Pp405 full presentation on new topical

      in Product  106 upvotes 1 week ago
      A new topical treatment, PP405, shows promising results for hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil. However, it may still need to be combined with DHT blockers for optimal results, and its long-term effectiveness remains uncertain.