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Accepting baldness and the various ways people try to cope with it, such as shaving, using medications like minoxidil and finasteride, or getting a hair transplant. Participants discussed how true acceptance of hair loss involves confronting difficult emotions such as grief for one's former appearance and identity, as opposed to simply superficially hiding it with a shaved head.

The post argues that Post-Finasteride Syndrome (PFS) is likely not real and suggests symptoms may be due to mental health issues or the nocebo effect. The conversation includes personal experiences with finasteride, highlighting both positive and negative effects, and emphasizes consulting doctors and using reliable sources for medication.

The conversation discusses skepticism and diminishing excitement around the hair loss treatment PP405 due to unclear trial results. It also mentions other treatments like finasteride, minoxidil, VDPHL01 (extended-release minoxidil), and GT20026 as potential options for hair loss management.

RU58841 is discussed as a hair loss treatment, with concerns about its effectiveness diminishing after two years due to androgen receptor upregulation. The user is hesitant to start using it, fearing it may worsen their condition over time.

People discussing their experiences with hair loss treatments found that switching from finasteride (Fin) to dutasteride (Dut) often resulted in improved hair thickness and health, despite some experiencing side effects or shedding phases. Some users switched due to diminishing results with Fin, while others were curious about the potential for better outcomes with Dut.

The user shared their 7-month progress using a topical solution of finasteride and minoxidil for hair loss, noting some improvement in hair thickness but acknowledging poor photo quality. They plan to switch to a combination of topical dutasteride, finasteride, and minoxidil, hoping for better results.

The conversation discusses androgen receptor degraders for hair loss, highlighting their potential advantages over traditional AR blockers like RU58841 and pyrilutamide. Concerns about the safety and cost of these treatments are also mentioned.

The conversation discusses switching from finasteride to dutasteride after many years to improve hair regrowth, with mixed experiences reported. One user has also used minoxidil and is hesitant to try RU58841 due to concerns about side effects and safety.

The user experienced significant hair improvement using rosemary and peppermint oils, alongside minoxidil, after other treatments like finasteride and pyrilutamide showed no results. They noticed reduced hair shedding and thicker hair, particularly in the mid and crown areas.

The user experienced side effects from oral finasteride and is considering microdosing topical finasteride mixed with minoxidil. They plan to mix Hims min/fin with Kirkland minoxidil to achieve a lower dose of topical finasteride.

The user is using a combination of 7% minoxidil, 0.2% finasteride, 0.5mg finasteride, RU58841, and daily microneedling but is not seeing hair regrowth after 5 months. Suggestions include being patient, reducing microneedling frequency, considering oral minoxidil, and possibly switching to dutasteride if no improvement after a year.

Minoxidil helps hair growth by increasing blood flow and prolonging the growth phase, but it doesn't address the root cause of hair loss, such as DHT sensitivity. Finasteride can help maintain some gains by blocking DHT, but stopping Minoxidil often leads to hair loss because the new hairs are dependent on it.

The user switched from finasteride to dutasteride due to side effects and is experiencing fewer side effects with dutasteride, though some scalp itching has occurred. Blood tests show elevated testosterone and estrogen, low DHT, and normal liver and cholesterol levels, leading the user to feel confident in the long-term benefits of dutasteride for hair regrowth.

The conversation is about switching from finasteride to dutasteride for hair loss treatment. Users shared mixed experiences with side effects and effectiveness, with some preferring to stick with finasteride if it's working.

Hair loss treatment should target dermal white adipose tissue (DWAT) to restore hair follicles. Potential remedies include tocopherol (vitamin E), botox, rosiglitazone, niacin, kojyl cinnamate esters, and ADP355.

Topical finasteride combined with minoxidil is used for hair loss treatment, with some users experiencing fewer side effects compared to oral finasteride. Morr-F, a topical solution, shows better results than minoxidil alone, with minimal adverse effects reported.

Male androgenetic alopecia is commonly treated with topical minoxidil and oral finasteride, both requiring continuous use. Other options include hair restoration surgery, dutasteride, light therapy, and camouflaging agents.

Extended-release oral minoxidil (VDPHL01) shows promising results for hair growth with improved safety, achieving significant hair count increases and minimal side effects compared to placebo. The treatment is designed to maintain effective concentrations while reducing side effects, making it a safer option for those who cannot tolerate standard minoxidil.

Some people have side effects from finasteride and dutasteride due to hormonal predisposition, especially if DHT dominant. Alternatives like RU58841, Pyrilutamide, and Breezula are suggested to target scalp androgen receptors without altering overall hormones.

Bee venom at 0.001% concentration was more effective than 2% minoxidil in promoting hair growth in mice, possibly due to increased growth factors and reduced inflammation. Caution is advised due to potential allergic reactions and the reliance on animal data.

The user plans to lower their oral minoxidil dose from 5 mg to 2.5 mg to reduce side effects like puffiness and hypertrichosis, while also using finasteride and accutane. They are considering caffeine serums for puffiness and discussing dietary changes or switching to topical minoxidil to address bloating.

Finasteride's potential side effects, especially sexual dysfunction, are discussed, with emphasis on hormonal balance between testosterone and estradiol. Users share experiences with finasteride, minoxidil, and dutasteride, highlighting the variability in side effects and the influence of mindset and lifestyle.

OP transitioned and used Spironolactone, Estradiol Valerate, Minoxidil, and dermarolling, resulting in significant hair regrowth. They advise this method may not be suitable for cis men.

A user shared their 4.5-month hair transformation using a homemade topical solution with 5% minoxidil and crushed finasteride pills, applied twice daily with weekly microneedling. They plan to switch to once-daily application with tretinoin gel to enhance absorption.

A 21-year-old experienced hormone changes after using self-made topical finasteride for hair loss, including a 20% decrease in DHT, a 47% increase in testosterone, and a 39% increase in estradiol. The user previously used minoxidil and microneedling but is now seeking ways to balance hormones, possibly through supplements or dosage adjustments.

The user has been using a strong combination of hair loss treatments for 16 months, including Finasteride, Minoxidil, Dutasteride, and RU-58841, but their hair loss has worsened. They're questioning whether their high testosterone levels or residual scalp DHT are causing further hair loss, with a reply suggesting that even small amounts of DHT can cause hair loss if one is sensitive to it.

Comparing the effectiveness and side effects of topical finasteride versus oral finasteride, with people sharing their experiences using both treatments to manage hair loss.

Doug-Sweeney has had positive results from using 1mg of finasteride and 5% minoxidil applied twice a day to treat his hair loss. Other users have also commented on how Doug-Sweeney looks younger with the improvements in hair quality.

A 29-year-old with hair loss (NW 3) uses microneedling, oral minoxidil, and ketoconazole shampoo. They are considering topical dutasteride after limited success with current treatments and are questioning why it's not more widely discussed.

A 24-year-old person who is worried about their hair loss after 14 months of taking finasteride and 11 months of minoxidil. Replies to the post suggested sticking with their current regimen, that shedding from one part may not be telogen effluvium, and that shedding is normal with these drugs and they should evaluate in two to three months.