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GlossaryDiphenhydramine

antihistamine used to treat allergies and induce sleep

Diphenhydramine, commonly known as Benadryl, is an antihistamine used to relieve symptoms of allergy, hay fever, and the common cold, such as rash, itching, watery eyes, and sneezing. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Additionally, it has sedative properties and is sometimes used as a sleep aid.

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community Putting antihistamine cream on scalp to fight inflammation and itchy scalp?

in Treatment 2 upvotes 3 years ago

Topical antihistamine creams, like diphenhydramine, are being considered for scalp inflammation and itchiness as an adjunct to standard hair loss treatments like minoxidil and finasteride. The user is cautious about oral antihistamines due to potential side effects and is exploring topical options.

community This guy is 113 and has more hair than most people on here.

in Satire 985 upvotes 5 years ago

A 113 year old man who has more hair than most people, and the conversation is discussing potential genetic factors that may be responsible for this. Possible treatments such as dermarolling and minoxidil, finasteride, and RU58841 are mentioned.

community Minox 5 Months + Finasterid 3 Months

in Progress Pictures 384 upvotes 1 year ago

The user has been using topical minoxidil for 5 months and oral finasteride for 3 months, reporting positive results without side effects. They apply minoxidil twice daily and take 1 mg of finasteride daily.

community The Big Fat Layer / Remedies: Cetirizine

in Treatment 11 upvotes 5 years ago

Treating hair loss with various remedies, such as Cetirizine and the Big3 complex (minoxidil, finasteride, and RU58841), which have properties like adipogenic, anti-fibrotic and anti-inflammatory. References to research studies are also included.

community Hydrocortisone cream

6 upvotes 9 years ago

A 30-year-old male with thinning hair and an itchy, oily scalp found that hydrocortisone cream eliminated dandruff and itching and seemed to thicken his hair. He avoided minoxidil and finasteride due to potential side effects and noted that Nizoral and Head & Shoulders worsened his symptoms.

community Betamethasone dipropionate 0.05 (sernivo spray)

in General 76 upvotes 1 year ago

A user was prescribed betamethasone dipropionate spray for a receding hairline, which caused skin peeling and depigmentation. They stopped using it and are considering alternatives like BPC-157/TB-500 for healing.

community How to mix topical cetirizine with minoxidil?

in Treatment 1 upvotes 2 years ago

The conversation discusses combining topical cetirizine with minoxidil for hair loss treatment and inquires about the safety and absorption through the skin, as well as the possibility of adding melatonin.

community Persistent Genital Itching on Finasteride Despite Clotrimazole Treatment

in General 31 upvotes 8 months ago

The user experienced genital itching while using finasteride and noticed a yellow bump, which improved with clotrimazole, but the itching persists. The discussion focuses on side effects of finasteride.

community How long after starting RU58841 did you notice itching subside?

in Research/Science 3 upvotes 1 month ago

RU58841 helped reduce scalp itching for some users within a week, while others experienced immediate relief. Some users reported initial irritation from the solution, possibly due to the carrier used.

community PG causing irritation when applying RU

in Research/Science 2 years ago

The user is experiencing irritation from using PG with RU58841 and is seeking alternative solutions like K&B in the UK. They report redness, itchiness, and flaky skin from the current treatment.

community RESULTS: 1% Clascoterone Cream. (3 months Jan-Mar 2026)

in Progress Pictures 14 upvotes 1 month ago

The user reported slight improvement in hairline using 1% Clascoterone cream over three months but found it too costly to continue. They expressed interest in trying a 5% concentration if it becomes available at a reasonable price.

community Piroctone olamine effective and better than ketoconazole?

in Product 2 upvotes 1 year ago

Piroctone olamine may be more effective and gentler than ketoconazole for dandruff and itchiness. Users report better results with piroctone olamine, but it is less available in the US.

community Dry flakes from topical fin use

in Finasteride/Dutasteride 2 upvotes 1 year ago

The user is experiencing white flakes and a greasy look from using a topical solution containing 0.025% finasteride, 8% minoxidil, 0.01% retinoic acid, and 1% hydrocortisone. Suggestions include reducing application frequency, using a brush to clean the scalp, and considering alcohol-free alternatives.

community Daily regimen - Witch Hazel, Finasteride, and Minoxidil

in Treatment 1 upvotes 3 years ago

The daily regimen includes oral finasteride, topical minoxidil, and witch hazel toner to reduce itchiness. Witch hazel is noted for its hydrating properties and affordability.

community Hydrocortisone helps with itch

4 upvotes 8 years ago

Hydrocortisone helps relieve scalp itchiness, possibly caused by minoxidil. Users discuss its effectiveness for managing this side effect.

community Can I use trichosol minoxidil before sleep?

in Minoxidil 3 upvotes 4 months ago

The user applies 2ml of a lotion containing 5% minoxidil, 0.3% finasteride, hydrocortisone butyrate, and cetirizine before bed, but it leaves a residue on the scalp. Another user suggests reducing the amount to 1ml, as 2ml results in a high finasteride dosage.

community Cassiopea Announces FDA Submission of New Drug Application for Clascoterone Cream 1%, the First New Mechanism of Action for Acne in Nearly 40 Years

in Technology 30 upvotes 6 years ago

The conversation is about a new acne treatment cream called Clascoterone Cream 1%, which is the first new mechanism of action for acne in nearly 40 years. One person joked about hoping their face will be as clean as their bald head after using the cream.

community Dermatologist prescribed Betamethasone dipropionate 0.05% lotion for hair loss.

in Product 8 upvotes 2 years ago

A user noticed increased hair loss and was prescribed Betamethasone dipropionate 0.05% lotion by a dermatologist. Another user suggested changing doctors and asking for finasteride instead.

community Is it safe to combine topical Dutasteride with topical RU58841?

in Finasteride/Dutasteride 3 upvotes 1 year ago

The user experienced severe side effects when using topical Dutasteride and RU58841 together and is considering using them at different times of the day. They are seeking advice on whether this approach might reduce side effects.

community 2.5 mg/ED dut and 1% pyrilutamide, still getting itch?

in Update 1 upvotes 1 year ago

The user switched from finasteride to 2.5 mg dutasteride daily and added 1% pyrilutamide to address persistent scalp itch, but the itch remains. They also use 2% ketoconazole and 2.5% selenium sulfide shampoo for temporary relief.

community Do any shampoos contain Piroctone Olamine in the US

in Product 3 upvotes 1 year ago

The conversation is about finding shampoos with Piroctone Olamine in the US for itch relief, as the user has not found relief with Keto shampoo, oral Dutasteride, and oral Minoxidil. Users suggest alternatives like Neutrogena T/Gel and online options, but note availability and price issues.

community Solution vehicle used by compounding pharmacy

in Research/Science 1 upvotes 2 years ago

The user is using 0.1% dutasteride, 1% minoxidil with 2% procapil and 0.005% caffeine in the morning, and 1% minoxidil with 2% procapil and 0.01% tretinoin at night. They are concerned about the solution vehicle's effectiveness in preventing systemic absorption and ensuring the products stay around the hair follicles.

community Ru58841 stops seb derm ( the itching)?

in Treatment 8 upvotes 2 years ago

RU58841 is discussed as a treatment that stops scalp itching when used with finasteride or dutasteride. The user is considering trying RU58841 due to persistent itching despite using the "big 3" treatments.

community Diagnosed with a mild form of Alopecia

in Treatment 5 years ago

A user experienced rapid hair loss and was prescribed Desonide cream for mild Alopecia. They are seeking feedback on its effectiveness and potential side effects.

community Topical finasteride carrier/vehicle

in Finasteride 135 upvotes 1 year ago

The user is considering making a homemade topical finasteride solution using an ethanol-based carrier. They are inquiring if a solution containing partially denatured ethyl alcohol and benzalkonium chloride is suitable.

community What is worth dissolving in topical minoxidil solution?

in Treatment 3 upvotes 1 year ago

Switching from minoxidil foam to topical solution and considering adding caffeine, melatonin, or cetirizine. Currently using 2.5mg oral minoxidil and 1mg oral finasteride, planning to ask for 0.5mg oral dutasteride and 5mg oral minoxidil.

community Ru58841 cleared my forehead acne

in Treatment 8 upvotes 9 months ago

RU58841 helped clear forehead acne. The user mixes it with 5% minoxidil and considers making a cream for acne treatment.

community concentration of my finasteride therapy

in Finasteride/Dutasteride 4 upvotes 9 months ago

The conversation discusses a topical finasteride therapy with hydrocortisone butyrate, estrone base, and breviline. A user suggests oral finasteride as a superior option.

community Best way to limit scalp irritation with topical fin?

in Finasteride/Dutasteride 1 upvotes 1 year ago

The user is experiencing scalp irritation from a compounded treatment of finasteride, minoxidil, and tretinoin. They are considering switching to a non-alcohol, propylene glycol-free formula with a lower tretinoin percentage to reduce irritation.

community Topical Dutasteride - Dosage / Frequency (Strut gel formulation)

in Treatment 16 upvotes 5 years ago

A user ordered a topical dutasteride gel with tretinoin for hair loss after unsatisfactory results with minoxidil and finasteride. Another user shared their experience with the same product, noting its pleasant smell and feel but difficulty in application and uncertainty about its absorption and frequency of use.