The group buy for CB-03-01, a topical anti-androgen for hair loss, was postponed and refunded due to issues with the product's form and solubility. The product, also known as Breezula, is an alternative to finasteride with fewer side effects, but its official release is delayed until 2021.
The conversation discusses using very low dose topical finasteride to achieve specific serum DHT reduction percentages. It concludes that finasteride dosage increases linearly between 5-30% DHT reduction but requires exponential increases for reductions up to 70%.
The user experienced erectile dysfunction from 1mg finasteride and sought advice on whether to continue, reduce dosage, or switch treatments. Suggestions included switching to topical finasteride, adding minoxidil, or trying dutasteride.
Finasteride prices vary widely across Europe, with some users opting to buy 5mg tablets and split them to save money. Many find 1mg tablets more expensive, and some suggest importing from countries like India for cheaper options.
The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.
The conversation discusses the use of Finastopic, a carrier for finasteride solutions by Isdin, and compares it to a standard propylene glycol (PG) solution. The user was prescribed a 1% finasteride solution using Finastopic and has been using a self-compounded 0.025% topical finasteride with minoxidil.
The user is experiencing severe side effects from finasteride, including sleep issues, depression, and gynecomastia, and is considering stopping the medication. They are exploring other treatments like RU58841 and dutasteride but are hesitant due to potential side effects.
The user is experiencing potential side effects from a 3-in-1 pill containing Finasteride, Minoxidil, and Biotin, including dizziness, blurry vision, and reduced libido. They are considering tapering off the medication as advised by their dermatologist to see if symptoms improve.
Topical finasteride concentrations and application amounts are debated, with concerns that mainstream solutions may use arbitrary concentrations. A 0.25% solution with a specific application method is suggested as more appropriate than higher concentrations.
AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.
OP wants to increase pyrilutamide concentration from 0.5% to 1% while already using finasteride. Users suggest waiting for a commercial 1% solution and caution against using grey market products.
Finasteride can be taken with or without food, but taking it with coffee on an empty stomach might cause diarrhea. It's generally safe to take finasteride at any time of the day.
Zeuss sublingual products for hair loss, including finasteride and a finasteride-free option, are discussed for their potential to reduce side effects through sublingual delivery. The inclusion of copper peptides is noted, but the high price is a concern without more user feedback.
Spraying or drinking topical minoxidil is dangerous and less effective than oral minoxidil. Proper oral minoxidil, like Loniten®, is recommended for safety and effectiveness.
The conversation discusses using aromatase inhibiting supplements like DIM and Grape Seed extract while on finasteride for hair loss treatment. Users share their experiences and opinions on combining these supplements with finasteride.
The user is experiencing white flakes and a greasy look from using a topical solution containing 0.025% finasteride, 8% minoxidil, 0.01% retinoic acid, and 1% hydrocortisone. Suggestions include reducing application frequency, using a brush to clean the scalp, and considering alcohol-free alternatives.
A user is seeking advice on using a DIY solution of topical finasteride (Fynzur 2.275mg/ml) mixed with minoxidil for hair loss. They are concerned about achieving full scalp coverage and prefer using a scalp applicator over a spray.
A user with diffuse thinning experienced no hair regrowth with finasteride or Avodart but slowed hair loss with Avodart. They are considering trying Minoxidil and are seeking advice on whether to use foam or liquid, and if combining it with other treatments could be beneficial, excluding micro-needling due to scalp irritation concerns.
The conversation discusses the safety, tolerability, and efficacy of oral Setipiprant tablets for treating androgenetic alopecia compared to finasteride. It mentions the high cost of Setipiprant on the black market and the trial's end date in September 2017.
The conversation is about a user running out of finasteride and seeking advice on alternatives or temporary solutions. Suggestions include trying different brands, using online prescribers, adjusting dosage, or considering a break from the medication.
User plans to switch from oral to .005% topical finasteride, using a solvent from minoxidilmax and later Essengen-F. They will monitor DHT levels and seek advice on solvents and sleep caps.
The conversation discusses increasing dutasteride dosage to 2.5mg for hair loss treatment, with suggestions to take multiple 0.5mg pills due to the unavailability of 2.5mg tablets in the US. Users also mention using ketoconazole and express skepticism about the effectiveness and safety of high doses.
Topical dutasteride may have limited absorption due to its higher molecular mass compared to finasteride, potentially affecting its efficacy in suppressing DHT locally. Microneedling might enhance dutasteride absorption, possibly offering stronger local DHT suppression with fewer systemic effects.
Breezula is being sold at Anagen Inc and Universal Labs, and users are discussing their experiences and results with it. There is also interest in the formulation process and inquiries about PP405.
PP405 might take 3-4 years to be available, but some claim Everychem offers a similar product, though its effectiveness is debated. Users discuss the risks of using untested grey market products and the potential for adverse effects.
The user experienced significant hair thickening after one year of using chewable finasteride (1.2 mg) and minoxidil (2.5 mg) without major side effects, except occasional low libido. The user sourced the treatments from Hims and noticed results around 5-6 months, with shedding lasting about two months.
A user asks about the appropriate zinc dosage to offset side effects while taking 0.5 mg of finasteride daily. Responses suggest zinc has a minor effect on hormones compared to finasteride.