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      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 1 year ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community five months dermaroller on penis

      in Satire  539 upvotes 2 years ago
      The conversation is a satirical discussion about using a dermaroller on the penis, with mentions of adding finasteride and doing exercises like cock pushups and planks. Some users joke about side effects and the absurdity of the topic.

      community 1 year on 0.5 dut + 2.5 oral min / crown progress

      in Progress Pictures  9 upvotes 1 week ago
      The user has been using 0.5 mg dutasteride and 2.5 mg oral minoxidil for a year, recently adding microneedling and topical minoxidil, with some improvement but the crown remains the weakest area. Consistency and realistic expectations are advised, as progress is slow and coverage is challenging with fine hair.

      community The Battle of Norwood (2024) | Dut 0.5 mg ED + Oral Min 5 mg ED

      in Progress Pictures  518 upvotes 1 year ago
      The conversation discusses hair regrowth using dutasteride and oral minoxidil, with the user reporting significant improvement in hair volume after combining these treatments. Some side effects mentioned include changes in libido and increased facial hair, but overall, the user is satisfied with the results.

      community What is up with the DUT hate on tressless?

      in Chat  31 upvotes 2 years ago
      The conversation is about the effectiveness of Dutasteride (DUT) for hair loss. Some users have had positive results with DUT, while others have experienced negative effects. Different opinions and experiences are shared, including the mention of Ashton Kutcher using DUT for 20 years without problems.

      community from fin to dut; from oral to topical minoxidil

      in Is this regrowth?  118 upvotes 1 year ago
      The user switched from finasteride to dutasteride and from oral to topical minoxidil, noticing better hair regrowth with the new regimen. They experienced no side effects from dutasteride and found topical minoxidil more effective than oral.

      community Almost 1 year dut + 3 month minoxidil

      in Progress Pictures  837 upvotes 2 years ago
      The post and conversation are about a user's progress with hair loss. The user used dutasteride (DUT) for 9 months and then added minoxidil for 3 months. They experienced significant improvements in hair growth and stopped their hair loss.

      community Being non responsive on dut and min

      in Is this regrowth?  6 upvotes 2 weeks ago
      The user is experiencing hair loss despite using dutasteride, minoxidil, and ketoconazole shampoo, and is concerned about continued shedding. Suggestions include checking for nutrient deficiencies, consulting a dermatologist, and considering other potential causes like seborrheic dermatitis or telogen effluvium.

      community Alternatives/unorthodox hairloss protocols to the big three

      in Chat  1 upvotes 3 months ago
      The conversation discusses alternative and unorthodox hair loss treatments, including RU58841, nandrolone, and dianabol, as well as theoretical approaches involving high doses of estrogen and selective estrogen receptor modulators. These methods are considered extreme and potentially harmful but are explored for those unable to tolerate traditional 5-alpha reductase inhibitors.

      community 4.5 year fin/.5 year dut progress update

      in Progress Pictures  182 upvotes 10 months ago
      The user maintained hair with finasteride for 4.5 years and noticed some progress with dutasteride after 6 months, experiencing reduced chest and facial hair. They did not use minoxidil and reported no side effects from either treatment.

      community Does anyone know the chemical formula for pelage pp405?

      in Research/Science  14 upvotes 1 year ago
      The conversation discusses the lack of public information on the chemical structure of PP405, a hair loss treatment, and the challenges of synthesizing it without a patent. It also explores a patent related to hydrogen-based topical formulations for reducing oxidative stress and inflammation.

      community Why don't people start with low-dose of dutasteride?

      in Finasteride/Dutasteride  25 upvotes 9 months ago
      The conversation discusses the use of dutasteride and finasteride for hair loss, with a focus on starting with low doses of dutasteride to match the DHT suppression of finasteride. It highlights the longer half-life and potential side effects of dutasteride, as well as the preference for finasteride due to its availability and research backing.

      community 36yo male, NW6, 2.5mth dut/minox

      in Progress Pictures  1 upvotes 1 year ago
      A 36-year-old male using dutasteride and minoxidil has seen significant hair regrowth, confirmed by a dermatologist and supported by before-and-after photos. He plans to increase his oral minoxidil dosage and add dermapen to his routine.

      community Is this supplement safe? Can it raise dht?

      in Product  1 upvotes 1 year ago
      The user has been using finasteride and minoxidil since October 2023 and is concerned if a supplement containing L-arginine, L-citrulline, Tongkat Ali, Tribulus terrestris, Avena Sativa, Gingko Biloba, Ginseng, Pyridoxine, Zinc Gluconate, and Saw Palmetto can cause hair loss. They report thicker and denser hair despite ongoing shedding.

      community 28 month update. 0.5 dut daily

      in Progress Pictures  16 upvotes 1 week ago
      A user reversed hair loss using 0.5 mg of dutasteride daily without side effects. Others noted hair thickening but questioned the absence of minoxidil use.

      community is there any news about pp405 please

      in Update  11 upvotes 1 year ago
      There is no new information on pp405, with data collection expected to finish by the end of 2025. Users are discussing the timeline for data analysis and completion of Pelage Pharmaceuticals' phase 2 study.

      community Hair Regrowth Protocol for the Brothers suffering

      in Treatment  57 upvotes 2 years ago
      The conversation discusses a hair regrowth protocol involving Dutasteride, Pyrilutamide, Stemoxydine, Minoxidil, Tretinoin, Oral Castor Oil, and L-Carnitine L-Tartrate. Some users are skeptical, particularly about the effectiveness and side effects of oral castor oil.

      community Chlorine dioxide: An effective product?

      in Research/Science  5 upvotes 1 year ago
      Chlorine dioxide was discussed as a potential hair growth treatment, with a method involving spraying it on the scalp and covering it with a cap. Concerns were raised about its safety, comparing it to bleach.