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      community Losing ground on Dut + Min + Ketoconazole

      in General  77 upvotes 11 months ago
      A 25-year-old male using Dutasteride, oral Minoxidil, and Ketoconazole shampoo is experiencing increased hair shedding and vellus hair growth along the hairline. Concerns are raised about whether this is a seasonal shed or a potential setback.

      community 3 Months Finasteride Log: Below Baseline

      in Finasteride/Dutasteride  7 upvotes 5 years ago
      A 23-year-old male is using finasteride (1mg daily), derma rolling, and Nizoral for hair loss treatment, experiencing increased shedding and side effects like anxiety, decreased libido, and fatigue. Despite no positive changes in hair after three months, he plans to continue finasteride and may consider RU58841 or CB as future treatments, avoiding minoxidil due to past negative experiences.

      community Hows the bro science feeling about 5mg oral min once a day or 2.5 twice?

      in Minoxidil  4 upvotes 9 months ago
      Oral minoxidil boosted vertex hair but not the hairline, with a stack including 5mg minoxidil, 2mg dutasteride, topical foam minoxidil, fluridil, and Nizoral. Users discuss dosing strategies, with some suggesting 2.5mg twice daily for sustained levels, while others recommend 5mg once daily based on clinical trials.

      community Finasteride + Monxidil Update pictures.

      in Progress Pictures  263 upvotes 1 year ago
      A user shared progress pictures after using finasteride and minoxidil for two years, showing significant hair improvement. The user started treatment at age 20 and reported no side effects.

      community Switch to Dut??

      in Finasteride/Dutasteride  10 upvotes 6 years ago
      Considering a switch from finasteride to dutasteride for hair loss treatment, and the use of minoxidil as a last resort due to its effects on hair texture.
      Should i be worried dut 6 months

      community Should i be worried dut 6 months

      in General  122 upvotes 5 months ago
      The user has been using finasteride and minoxidil, then switched to dutasteride and minoxidil for six months without significant results, noticing thinning after increasing creatine dosage. They plan to consult a dermatologist to explore potential causes beyond androgenetic alopecia.

      community Has anyone experienced this? Loss of density with DUT. please help

      in Chat  6 upvotes 1 year ago
      Switching from finasteride to dutasteride led to hair density loss, prompting consideration of returning to finasteride. Consistency with dutasteride and adding RU58841 did not prevent the loss, and users suggest giving dutasteride more time or consulting a dermatologist.

      community How to ease off oral minoxidil?

      in Minoxidil  1 upvotes 1 year ago
      The user experienced heart palpitations after increasing their oral minoxidil dosage and starting a new topical minoxidil formulation. They wish to stop oral minoxidil for heart health and continue with topical minoxidil.

      community Topical dutasteride results 7 weeks progress

      in Progress Pictures  10 upvotes 1 month ago
      A 22-year-old male is using topical dutasteride, minoxidil, tretinoin, and microneedling for hair loss, experiencing some side effects like mild ball pain and initial shedding but seeing progress in hair thickness. He plans to increase the dutasteride dose and has tried various treatments, including finasteride and RU58841, with differing side effects.

      community 4 1/2 months of Dut and Oral Min Update

      in Update  374 upvotes 4 months ago
      Significant hair regrowth was achieved after 4.5 months using 0.5 mg Dutasteride and 5 mg oral Minoxidil. Tips on obtaining prescriptions and discussions on effectiveness and side effects were also shared.

      community Has anyone got results from pyrilutamide?

      in Research/Science  3 upvotes 6 months ago
      The user maintained hair with minoxidil, alfatradiol, and fluridil after stopping finasteride due to erectile dysfunction. They recently added pyrilutamide and are seeking feedback on its effectiveness after six months of use.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 1 year ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Just got my bloodwork done, should I worry?

      in Finasteride/Dutasteride  8 upvotes 4 years ago
      The conversation discusses concerns about potential side effects, specifically gynecomastia, from taking 1mg of finasteride every other day for hair loss. Bloodwork results were shared, but more information was requested to provide advice.

      community Does 2.5 mg of Dutasteride daily really make a substantial difference vs. 0.5 mg daily? If so, why? I thought you just pissed all the excess out, anyway. I’d like some direct user experience, please, especially if you tried one vs. the other.

      in Finasteride/Dutasteride  8 upvotes 2 months ago
      Higher doses of Dutasteride, like 2.5 mg daily, may offer slightly more hair growth but come with increased risk of side effects, such as sexual dysfunction and sleep disturbances. Many users suggest starting with a lower dose, like 1 mg, to minimize side effects while still achieving effective results.

      community My experience with Pyrilutamide

      in Update  3 upvotes 2 years ago
      The user experienced a slight decrease in hair shedding and scalp itch, and reduced sebum production using Pyrilutamide, but stopped due to chest pain, breathing difficulties, and heart issues. They felt normal a week after discontinuing and doubted FDA approval for the drug.

      community Do you think clascoterone is overhyped

      in Treatment  14 upvotes 1 month ago
      Clascoterone is considered overhyped and not as effective as finasteride or dutasteride, but it may be useful as a supportive treatment in combination with other therapies. Users express skepticism about its effectiveness compared to clinical trials, with some suggesting it could be beneficial for those who cannot tolerate other treatments.