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330-360 / 1000+ resultscommunity Pelage are still talking about phase 2a results of PP405
PP405 shows promise for hair regrowth, with new hairs observed in 66% of patients in just 27 days. The discussion also mentions Minoxidil, finasteride, and RU58841 as potential treatments.
community There is something off with DUT and it’s time we stop ignoring it
Dutasteride and finasteride for hair loss, with dissatisfaction expressed about dutasteride and consideration of switching back to finasteride. Users share varied experiences, noting individual responses to treatments differ.
community Has anyone gotten pp405 on the grey market yet?
People are discussing the use of an untested hair loss treatment called PP405, which is not available on the grey market. Some users are trying a mimic formulation called HP3, reporting thicker hair but no new growth yet.
community 1 year! 1mg fin/topical min, currently adding dut 👍
The user achieved impressive hair regrowth using 1mg finasteride and topical minoxidil, and is now adding dutasteride due to recent diffuse thinning. They experienced initial side effects with finasteride but no longer have issues.
community Shedding stopped and micro inflammation is gone after adding dut 1.5 mg for 1 month
Dutasteride 1.5 mg stopped shedding and reduced scalp inflammation in one month, unlike finasteride. The user also uses minoxidil but saw no results until adding dutasteride.
community Progress - one year with fin 1mg (oral) and min 5% foam (topical)
community Peptide Therapy -> GHK-CU, ZN-Thumulin, PTD-DBM
The conversation is about the use of peptide therapies for hair loss, specifically GHK-CU, ZN-Thymulin, and PTD-DBM. The user is seeking feedback on the effectiveness of these treatments from those who have tried them.
community DUT 1 Year Progress Pictures… any difference?
The user switched from finasteride to dutasteride and noticed some hair density improvement after a year, despite initial shedding. Their regimen includes dutasteride, oral and topical minoxidil, Nizoral shampoo, and biotin with vitamin D.
community I ran PP405 for 6 months. Is this regrowth?
community How much scalp dht does dutasteride 1mg, 1.5mg, and 2mg block?
Dutasteride at 0.5mg blocks 50% of scalp DHT, while higher doses like 1mg and 2.5mg block more, with 2.5mg blocking up to 80%. Some users report better results with lower doses, and there's confusion about the effectiveness of different dosages on scalp versus serum DHT.
community Japan Uses Low Dose Dutasteride (0.1mg). Minimal exposure and hair growth success.
Low-dose dutasteride (0.1 mg) is effective for hair growth, potentially more so than finasteride, with fewer side effects. East Asians may respond well to these treatments due to hair characteristics.
community We always hear that DUT only lowers scalp DHT by 50% (fin at 40%) but a study within the hair follicle itself shows that DUT nukes DHT to near undetectable levels... so which is it??
Dutasteride significantly reduces DHT levels in hair follicles, potentially more effectively than previously thought. The discussion highlights differences in DHT measurements and the impact on hair loss treatment.
community Anything stronger than DUT out there?
The conversation discusses seeking a stronger treatment than Dutasteride (DUT) for hair loss. Suggestions include combining DUT with RU58841, increasing DUT dosage, and using transgender hormone replacement therapy or testosterone blockers, though some options may have feminizing side effects.
community You NEED this if You’re Taking Fin/Dut
DIM is suggested to help with estrogen metabolism for those on finasteride or dutasteride, potentially reversing side effects like fat gain and mood changes. Some users doubt its effectiveness, recommending lifestyle changes or consulting a doctor instead.
community 4.5-month progress; dut 3x/week + topical min 1-2x daily + microneedling 2x/month
Hair loss progress in 4.5 months using dutasteride 3x/week, topical minoxidil 1-2x daily, and microneedling 2x/month. Users praised the significant improvement.
community Setipiprant/PGE2 feedbacks?
The conversation discusses using PGE2 as a hair growth stimulant, comparing it to minoxidil, and considering the addition of Setipiprant. Concerns about side effects like skin damage and cost are also mentioned.
community So the cure for Nw7 is verteporfin
community DHT LEVEL IS 700pg/ml AFTER 8 MONTHS OF DUTASTERIDE
The user had high DHT levels after 8 months on dutasteride, questioning the drug's authenticity. They got dutasteride from a legitimate source and will update on progress.
community When is PP405 trial results medical meeting scheduled?
community How likely do you think it is for PP405 to come out?
PP405 is a potential new hair loss treatment that works through metabolic pathways rather than hormonal ones, with an estimated market release between late 2027 and 2029. Current alternatives to finasteride include minoxidil, pyralutamide, fluridil, and RU58841, with hair transplants also being a viable option.
community PSA: You can’t donate blood if you are taking finasteride
Finasteride users cannot donate blood due to potential risks to pregnant women, requiring a one-month cessation before donating. Dutasteride requires a six-month deferral, and topical applications are not restricted.
community Today was Last update on pp405
A new hair loss treatment, PP405, is moving from phase 2A to 2B in clinical trials, sparking discussions about its potential to regrow dormant hairs and its impact on existing treatments like Minoxidil and finasteride. Some users express skepticism, while others are hopeful about its future effectiveness.
community Don’t Get Too Hyped About PP405. We've Seen This Movie Before.
PP405 is a new hair loss treatment showing early promise with a 20% hair density increase, but skepticism exists due to past failures of similar treatments like Pyrilutamide, RU58841, and Bimatoprost. Users debate its potential effectiveness, with some hopeful due to Google's involvement, while others urge caution without more evidence.
community DrPen etc vs Stamp 2025 product update +can you still get Pen refills in the future?
The user is considering switching from a stamp to a pen for hair treatment due to poor results with the stamp. They are concerned about the availability of pen refills and are seeking better outcomes with the pen.
community 6 Month Progress Pics - Dutasteride
The conversation discusses hair loss and the use of Dutasteride for treatment. One participant strongly supports the use of Dutasteride.
community Does 0.5 mg of finasteride reduce SCALP DHT the same as 1 mg?
The conversation is about whether 0.5 mg of finasteride reduces scalp DHT as effectively as 1 mg. Users suggest that even lower doses like 0.05 mg can significantly reduce scalp DHT.
community 20m. 1mg Fin. This is Week 11.
community Doctor prescribed dut, not sure if they were correct
The user is concerned about using dutasteride for potential hair loss, fearing it might accelerate balding if not effective. They are unsure about the doctor's diagnosis and are considering starting with finasteride instead.
community Reminder: You cannot donate blood if you are taking Fin or Dut
You cannot donate blood if you are taking finasteride or dutasteride due to potential risks to pregnant women. Finasteride has a shorter wait time to donate blood compared to dutasteride, and both oral and topical forms can disqualify you from donating.